Thomas Pilgrim

Diastolic vibration of the anterior leaflet of the mitral valve as a result of aortic regurgitation (Austin Flint).

Inflammation after TAVI: an emerging therapeutic target? GLUCO-TAVI and CO-STAR provide convergent but inconclusive signals across mechanistically distinct therapies. eurointervention.pcronline.com/article/inflam…

Platelet counts may serve as a reliable marker for predicting subclinical leaflet thrombosis after TAVI: a normal platelet count at any time between TAVI and hospital discharge may effectively exclude the presence of subclinical leaflet thrombosis. doi.org/10.1093/ehjvsh…

Bicuspid anatomy can pose a significant challenge for TAVI: the combination of a substantial AVC calcium burden and a prominent raphe may define a particularly high risk phenotype. #JACCImaging authors.elsevier.com/a/1mo9j,i2Xs4E…

In a post hoc analysis of the SCOPE trial, patients with obstructive CAD who underwent TAVR had comparable survival, patient-reported health status, and VARC-3 clinical efficacy compared with patients without CAD through 3 years of follow-up. jamanetwork.com/journals/jaman…

Exploring the inflammatory response to Transcatheter Aortic Valve Replacement - opening the door to new therapeutic strategies? authors.elsevier.com/sd/article/S19…

In this RCT in TAVI patients, treatment with colchicine was associated with a lower risk of new-onset rhythm disturbances and subclinical leaflet thrombosis compared with placebo. The inflammatory response to TAVI may represent a novel therapeutic target. rdcu.be/eQ5oO

In this analysis of >1,000 TAVI patients, we demonstrate that underexpansion of balloon-expandable transcatheter aortic valves, as assessed by fluoroscopy, is associated with an increased risk of hemodynamic valve deterioration at mid-term follow-up. authors.elsevier.com/sd/article/S19…

The extent of cardiac damage significantly affects 10-year survival of patients with moderate and severe aortic stenosis. Cardiac damage staging might be as important as aortic stenosis grading in defining the prognosis of patients with aortic stenosis. authors.elsevier.com/sd/article/S19…

Contemporary Incidence and Procedural Volume of Transcatheter Aortic Valve Reintervention jamanetwork.com/journals/jamac…?

Procedural factors determine transcatheter aortic valve performance. The CODE framework integrates key parameters to systematically optimize TAVR outcomes. authors.elsevier.com/sd/article/S27… @JACCJournals @DomAngellotti

Transcatheter Aortic Valve Replacement With Balloon- Versus Self-Expandable Bioprostheses for the Treatment of Bicuspid Aortic Valve Stenosis ahajournals.org/doi/10.1161/CI…

Non-coaxial transcatheter aortic valve deployment relative to the native annulus is associated with impaired valve early safety and increased risk of bioprosthetic valve failure 1 year after TAVR. jacc.org/doi/10.1016/j.…

In the SCOPE I trial, patients with frailty had a similar improvement in patient-reported health status measures after TAVR, but a higher risk of unfavorable outcomes throughout 3 years of follow-up. authors.elsevier.com/sd/article/S27…

CIDRZ and the University of Bern are teaming up to fight #RheumaticHeartDisease (RHD) in Lusaka! A study targeting children aged 5–16 in 12 schools will assess the effectiveness of a school-based programme in preventing RHD in high-prevalence areas.

In the Bern TAVI registry, hemodynamic valve deterioration occurred in up to 1 in 4 patients throughout 10 years post-TAVI and was associated with a 5-fold increased risk of aortic valve reintervention. #JACCINT authors.elsevier.com/sd/article/S19… @BashirAlaour @FabienPraz @StefanStortecky

Aortic Stenosis and Coronary Artery Disease: Decision-Making Between Surgical and Transcatheter Management doi.org/10.1161/CIRCUL… @DaijiroTomii

Echo screening of TB patients facilitates early detection of CV involvement. Routine echo at baseline in all newly diagnosed TB patients may allow for timely medical management and prevent complications such as constriction and heart failure. @JACCJournals #fig4" target="_blank" rel="nofollow noopener">sciencedirect.com/science/articl…

TAVI in patients with bicuspid aortic stenosis: navigating anatomical challenges and tackling a cocktail of risks jacc.org/doi/10.1016/j.… @AMaznyczka

Fibrotic versus calcific aortic stenosis in patients undergoing TAVR. authors.elsevier.com/a/1k83T6uPJvuW… @AMaznyczka @DomAngellotti @DaijiroTomii @chrisgraeni @DaryoushSamim @pbaekke @StefanStortecky

Timing of intervention in patients with aortic stenosis. authors.elsevier.com/sd/article/S19…