Aleksandar D. Kostic

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Aleksandar D. Kostic

Aleksandar D. Kostic

@adkostic

I study the #microbiome and #immunology at @harvardmed and @joslindiabetescenter

Boston, MA شامل ہوئے Mart 2012
652 فالونگ438 فالوورز
Aleksandar D. Kostic
Aleksandar D. Kostic@adkostic·
"The universe is not only stranger than we imagine, it is stranger than we can imagine." Seems especially true of the microbiome. Congrats to my grad student Braden Tierney on identifying "singleton" genes, a new window into microbiome diversity. CellH&M: bit.ly/2Hm0xsP
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Aleksandar D. Kostic
Aleksandar D. Kostic@adkostic·
@NetSpatial Hadn’t seen this before, very interesting. I wonder if in tissue-appropriate tumors there could be added lactate “mop” bacteria if it could have some therapeutic value. Though making a dent on systemic lactate levels is harder, the liver is extremely efficient at metabolizing it.
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Timothy Olsen, PhD
Timothy Olsen, PhD@NetSpatial·
@adkostic article: Reexamining cancer metabolism: lactate production for carcinogenesis could be the purpose and explanation of the Warburg Effect academic.oup.com/carcin/article… #ExerciseOncology
Timothy Olsen, PhD@NetSpatial

So - #gut bacteria is #lactate energy source for runners.. & a #marathon #exercise bout will stimulates growth of the #Veillonella that converts #lactate to fuel ie #propionate.. FANTASTIC! Q: @doctorinigo Could this help #mitigate #carcinogenesis? nature.com/articles/s4159…

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Aleksandar D. Kostic
Aleksandar D. Kostic@adkostic·
@veiga_pat Thanks Patrick! Fermented foods to increase lactate concentrations in the gut could very well help promote Veillonella, but perhaps there is no better strategy than exercise (though eating kimchi from my couch sounds much more appealing than strapping on running shoes)
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patrick veiga
patrick veiga@veiga_pat·
Congrats Alex! Very nice work! I wonder if eating lactate enriched products (such as fermented foods) prior physical effort , could ‘train’ your microbiome to more efficiently convert muscle-derived lactate into SCFA?
Aleksandar D. Kostic@adkostic

Long time brewin', but thrilled to see our work describing a human-microbiome metabolic symbiosis in exercise published in Nat Med today: go.nature.com/2LeBAC0. Extremely proud of my grad students Jacob Luber and Ted Chavkin, and the guy that started all of this Jon Scheiman.

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Aleksandar D. Kostic
Aleksandar D. Kostic@adkostic·
Long time brewin', but thrilled to see our work describing a human-microbiome metabolic symbiosis in exercise published in Nat Med today: go.nature.com/2LeBAC0. Extremely proud of my grad students Jacob Luber and Ted Chavkin, and the guy that started all of this Jon Scheiman.
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Aleksandar D. Kostic
Aleksandar D. Kostic@adkostic·
To my #genomics and #microbiota colleagues: though @Novogene_US's prices may lure you in, be wary trusting time-sensitive business (is there any other kind?) to them. The turnaround timeline is a complete mystery from day 1 and they'll keep you guessing past your grant deadlines
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Aleksandar D. Kostic ری ٹویٹ کیا
Elon Musk
Elon Musk@elonmusk·
@ariannahuff Ford & Tesla are the only 2 American car companies to avoid bankruptcy. I just got home from the factory. You think this is an option. It is not.
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Aleksandar D. Kostic
Aleksandar D. Kostic@adkostic·
My new lab at Joslin Diabetes Center & Harvard Medical School is up and running. We are now hiring postdocs! lnkd.in/djuWv-c
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Tommi Vatanen
Tommi Vatanen@tvatanen·
We are excited to publish our findings on infant gut microbiome and the hygiene hypothesis cell.com/cell/abstract/…
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Benjamin Casterline
Benjamin Casterline@bwcasterline·
Bacteroides strains durably colonize some infants, block TLR4, prevent endotoxin tolerance, increase autoimmune risk cell.com/cell/abstract/…
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Drizzy
Drizzy@Drake·
To the city I love and the people in it...Thank you for everything #VIEWS
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