brian

THEY SENT FOUR HUMAN BEINGS 252,756 MILES AWAY, WENT FULLY AROUND THE MOON AND BROUGHT THEM BACK TO LAND IN THE PRECISE LOCATION THEY WANTED EVERYONE WHO WORKED ON THIS IS THE COOLEST PERSON ON EARTH

@xalertnow useless adults, dog would've been disemboweled

🚨 CHINA 🇨🇳‼️ DESMEMBRADO POR UN PERRO 🐕: Un niño pequeño sufrió el ataque desgarrador de un pitbull, que le destrozó la pierna a mordidas. Irresponsabilidad de los dueños del animal.

Breaking Bad without Skyler White

@anishmoonka okay but what about cats

Your dog could soon get a daily pill that slows aging. 1,300 dogs are already testing it across 70 vet clinics, and it just passed its second FDA safety review in January. The drug is LOY-002. A San Francisco startup called Loyal makes it. Celine Halioua started the company in 2019 when she was 24. They have raised $250 million so far, including $100 million in February from Baillie Gifford, the same firm that bet early on Tesla and Amazon. The simplest way to explain what it does: if you put a dog on a strict diet where it eats way less food, that dog tends to live about two years longer. Cancer and arthritis both show up later. The body just ages more slowly. LOY-002 gives the dog those exact benefits without actually eating less. The dog keeps its appetite and its weight; it just ages more slowly. The trial is called STAY. Half the dogs get a beef-flavored pill every day, and the other half get a fake version that looks and tastes the same. The FDA reviewed safety data from over 400 dogs. Zero serious side effects, even at five times the normal dose. Loyal has now cleared two of three hurdles for conditional approval, which basically means they could start selling the drug while the full trial keeps going. The last piece, manufacturing, goes to the FDA in 2027. One thing the tweet gets a bit wrong: the pill is for senior dogs aged 10 and older, at least 14 pounds. And Loyal is being careful about the "years" claim. Right now, they are saying at least one extra year of healthy life. They want to prove more, but the trial needs to finish first. If LOY-002 gets approved, it would be the first drug the FDA has ever cleared to slow aging in any species, human or animal. Loyal also has two more drugs coming for big breeds like Great Danes and Rottweilers. Those dogs die younger partly because of a hormone called IGF-1, which makes them grow fast but also wears their bodies out quicker. And a separate project backed by a $7 million grant from the NIH (the agency that funds medical research) is testing a human organ transplant drug called rapamycin in 580 dogs to see if it slows aging, too. The global pet care market hit $261 billion last year. A once-a-day pill that gives your dog even one extra healthy year could easily become one of the best-selling veterinary drugs on the planet.

@RyLiberty lmao

Is anyone shocked?

@nojumper future astronaut

Sneako gets pressed in NYC.

@Apni_Isllah @MiddleEast_Eng yall same as the ✡️

@MiddleEast_Eng This is the culture of non Muslims. Thank God I'm a Muslim and I'm proud of it.

This is how the moment a girl allowed another person to kiss her in front of her boyfriend was captured on camera, with her boyfriend's eyes filled with tears.

@EmmanuelDi65069 very good ragebait

Let's be honest, modulo yuji haven't even pulled a better feat than Sendai colony yuta, he's just over hyped 💔

🇯🇵 I often see endless third world resentment toward the West and feel only pity. Hiroshima & Nagasaki were destroyed by atomic bombs. We lost everything. We didn't scream about trauma or demand endless reparations. We rebuilt. Today these cities are beautiful. So, drop the victimhood. Stop blaming history. Change and build something or otherwise get used to being disliked.

@nicksortor Bandaid fix we all know the real answer ¯\_(ツ)_/¯

🚨 BREAKING: The State of Indiana will be CANCELING ALL commercial driver licenses for illegals at midnight TONIGHT, per the Lt. Governor FINALLY! EVERY SINGLE state should follow Indiana’s lead immediately.

@TheOnlyDSC 😔

Tokyo and NYC subways have the same problem.

@ItssSlothyy Hakari and Kashimo 100%

Other than 120% Potential, and Triple Domain Expansion What is the next major-iconic manga panel to be animated? To me, it’s clear as day

@kangminlee bro we on the same flight rn

I just know this guy is seething over the America-Japan friendship exploding on this site.

@RT_com Kill

ALL 67 DEAD AS BLACK HAWK MIDAIRS AMERICAN AIRLINES JET — 1ST SHOT Deadliest since 2001

.@AmericanAir I am a japanese man can I have a free business class upgrade to make up for hiroshima

@CasualMMA what about Izzy gettin dogwalked for 5 rounds by Strickland?

Magomed Ankalaev still holds the record for the most pathetic performance in UFC title fight history

@echoesofworld Yooooo i took the same exact photo at a different time!!

Kyoto, Japan

these niggas on Grailed something else boy lmfaoooo

Everyone needs to visit Japan in their lifetime

He really compressed 4 years of therapy into 60 seconds.