Cody J. Smith
758 posts
@cssmity
Scientist and Professor at University of Notre Dame; Father and Husband at House of Smith. opinions are my own.
Microglia can selectively clear neurons, but what else do they eat? @FChrisBennett & @nachoriko explore a #PLOSBiology study showing that #microglia also cannibalize other microglia, followed by microglial necroptosis Primer: plos.io/4f7sXEs Paper: plos.io/3Aj1JvE
Really excited about our new preprint from the lab about microglia lifespan and cannibalism. Congrats to Hannah Gordon for her hard work! Read more below about the story 👇🧵👇 @ZTSlab biorxiv.org/content/10.110…
Microglia are considered long lived, but @cssmity &co show that individual embryonic #microglia die within 3 days after clearing neural debris and are cannibalized by existing microglia, paradoxically leading to additional microglial death #PLOSBiology plos.io/3Aj1JvE
Neuroscience faculty job alert! The University of Notre Dame is hiring 5 tenure-track positions in cellular, molecular, or computational neurobiology. Come be my colleague in a welcoming and inclusive environment. Please share! apply.interfolio.com/152596
💡 Innovation + 👩🏾🔬🧑🏼🔬 Collaboration = 🧠 Increased understanding of the brain Meet 64 interdisciplinary teams working to expand our understanding of neuroscience + find treatments for neurodegenerative diseases czi.co/42K4IqJ
Did you know that the @NIHDirector’s Early Independence Award supports junior #scientists to launch independent careers? Look at how this year’s awardees are “skipping the postdoc” and will pursue their own #biomedical and #BehavioralResearch commonfund.nih.gov/earlyindepende… #NIHHighRisk
.@cssmity &co show that satellite #GlialCells in the #PNS display isolated spontaneous Ca2+ transients, sensitive to #mechanosensitive protein #Piezo1, revealing a role for #mechanobiology in the activity of developing neural cells #PLOSBiology plos.io/3t0Ko6w
I am excited for our most recent publication led by Jake Brandt (now postdoc with @SD_Ackerman). Jake's work reveals spontaneous activity in DRG glia in the early phases of its assembly. Interestingly to us, a part of the activity was dependent on mechanical channels. 🧵👇
