DNA Replication Lab

Delighted to share our pre-print identifying human DNA replication initiation sites on single molecules by @nanopore sequencing. Key findings 1/6 biorxiv.org/content/10.110…

🧬 Do you want to learn how to use @nanopore sequencing to detect DNA base modifications? Our new course will include experimental design with important considerations for generating ultra-long #Nanopore #sequencing reads. okt.to/mO7ogt

I visited @CNieduszynski in Norwich, UK, and enjoyed discussions with many members of his lab. Many exciting projects are goinig on! Hopefully, we will keep in touch! I also loved the relaxing atmosphere of the city. Thank you for hosting me, Conrad.

🧬 This morning at @BiochemSoc #DNAReplication meeting in Cambridge, catch Dr Anna Rogers speaking about her work during the 'replication fork progression' session. @DNARepliLab okt.to/qyVfKM

@nanopore @EarlhamInst Great work by Jamie Carrington and Rose Wilson @rhc_wilson collaborating with Sathish @unintegrable and the @EarlhamInst Technical Genomics Group @DrKarimGharbi 6/6

@nanopore @EarlhamInst However, most (80%) DNA replication initiation sites are dispersed throughout the genome with no specific chromatin signature and are missed by cell population studies. 5/6

Delighted to share our pre-print identifying human DNA replication initiation sites on single molecules by @nanopore sequencing. Key findings 1/6 biorxiv.org/content/10.110…

GUIDE: Learn how to use the #YeastMoClo and #MYT kits from the labs of @johndueber and @ProfTomEllis in a new series of technical blogs from Dr Anna Rogers, for your next budding yeast transformation. 🧬🧫 ➡️ okt.to/NvZiJy @DNARepliLab #yeastgenetics

Telomere-to-telomere Schizosaccharomyces japonicus genome assembly reveals hitherto unknown genome features: onlinelibrary.wiley.com/doi/full/10.10… @Yeast_Journal spoiler: fission yeast will take over the 2024 cover...😱

⏰ Applications are closing soon for our Postdoctoral Research Scientist role working on single-molecule analysis of Human #DNAreplication using @nanopore sequencing. 🗓️ Apply by: 07 March 2024 okt.to/agO2V8 #cellbiology #molecularbiology #researchjobs #postdocjobs

We're recruiting for a #postdoc to join the @DNARepliLab with @CNieduszynski at the Earlham Institute. In collaboration with @NIG_idenken you will apply @nanopore sequencing to characterise the dynamics of human genome replication on single molecules. okt.to/NhK5TS

We're recruiting for a #postdoc to join the @DNARepliLab with @CNieduszynski at the Earlham Institute. In collaboration with @NIG_idenken you will apply @nanopore sequencing to characterise the dynamics of human genome replication on single molecules. okt.to/qrMzcL

New post-doc position: Single molecule analysis of human DNA replication @nanopore sequencing @EarlhamInst Collaborations with ONT and Kanemaki group @NIG_idenken Informal enquiries welcome. Apply here: okt.to/GdXiTM Closes: March 7th Please RT

Schizosaccharomyces versatilis represents a distinct evolutionary lineage of fission yeast: onlinelibrary.wiley.com/doi/abs/10.100… #FantasticYeast @DNARepliLab @Yeast_Journal

Delighted to have been part of this collaboration: Design, Construction, and Functional Characterization of a tRNA Neochromosome in Yeast with @caiyizhi @DSchindler_PDR @SynbioRoy @JefBoeke @EarlhamInst authors.elsevier.com/sd/article/S00…

2. Resolving Nuclear Conflict Join us & @WHaerty group to investigate Transcription-Replication conflicts and #genomestability using @nanopore sequencing. @EarlhamInst @NRPBIODTP t.ly/HE_KH

We have two new fully funded PhD opportunity in our group @EarlhamInst in the @NRPBIODTP 1. Causes and consequences of short tandem repeat instability Join us, @YiliangDing & @WHaerty groups and use @nanopore sequencing to investigate #genomestability t.ly/q5flT

We're pleased to announce two #fissionYeast pre-prints in collaboration between @EarlhamInst and @TheCrick S. versatilis represents a distinct species doi.org/10.1101/2023.0… and T2T S. japonicus assembly reveals hitherto unknown genome features doi.org/10.1101/2023.0…