MuscleX_Lab

We are hiring a beamline scientist to run the fiber diffraction program at BioCAT. Please spread the word! bio.aps.anl.gov/news/biocat-jo…

The Biophysics Collaborative Access Team Awarded $8M Grant. musclexlab.com/the-biophysics…

#OPENACCESS: A higher ATP concentration turns thick myosin filaments into an ON state, leading to altered cross-bridge kinetics. These X-ray data correlate low ATP levels to the inactivated myosin state observed in certain heart diseases. buff.ly/6ZpKw3J

Our symposium is just around the corner—don’t forget to register to receive the Zoom link for the event. We look forward to seeing you there. iit-edu.zoom.us/meeting/regist… musclexlab.com/musclex-sympos…

Excited to share BioCAT P30 grant received an outstanding overall impact score of 16! Grateful that the Fiber Core, which I lead, earned a perfect score of 10—a testament to the incredible work of our team and user community. We look forward to serve the field in the years ahead.

The “sound” of the heart beats!

The PI of BioCAT, Thomas Irving, will give a talk today at 3:15-4:30pm CST titled “30 years of Muscle Diffraction at BioCAT - What have we learned about muscle contraction?” Welcome to join iit-edu.zoom.us/j/89428128891?…

It was very nice to welcome our muscle users @HesselAnthony @mikuehn8 @vivekpjani back after two years for @advancedphoton upgrade. BioCAT remains the state-of-art facility for muscle X-ray diffraction. Proposal for next run due in two days!

@jonathankirk @LoyolaChicago Henry is the poster boy 👍

The @LoyolaChicago announcement that we obtained R1 status (the highest research university classification) used a picture from my lab. You can tell it's from my lab because the microscope is named after a Star Wars character.

A definition of a long haul. Very glad to see this one came through after years of work.

Very productive run at @CHESS_user with @vivekpjani and Marcus. We collect patterns from human heart tissue (HFpEF, HFrEF, HCM, SVD) probably for the first time ever there, and more patterns from animal hearts. Looking forward to come back soon!!!

Very nice to see this project in the press!

Congrats @vivekpjani well deserved

@OchDr Really hope it won’t, but it is probably a wishful thinking

First decoration at the new Fulton Lab

We are glad to share that we got all the beam we expected from the new @advancedphoton into our experimental hutch, ~4 × 10^13 photons/sec at 250um ×250 um unfocused. We expect to welcome users back in the near future after the scientific commissioning.

@OchDr Yes

@OchDr When they say we are really sorry for the delayed response, they don’t really mean it.

@PKH_Lab Qingdao is very close to my hometown, enjoy

I was invited to present our lab's simulation work on the myofilament protein ABLM1 at this year's meeting of #istcp2024 in Qingdao, China! Happy to also visit with my colleague Yi Wang from the Chinese U. of Hong Kong.

Kyrah L. Turner (@wsusbs) et al. discovered that the structural and functional effects of myosin regulatory light chain #phosphorylation are amplified by increases in sarcomere length and [Ca2+] 💡 📜Read the #Research here: buff.ly/3zG9DPr