Timothy Saunders

1.7K posts

Timothy Saunders

Timothy Saunders

@TimESaunders

trained physicist now running a developmental biology lab. interested in how complex shape and form emerges during embryogenesis.

Warwick, England Tham gia Kasım 2013
543 Đang theo dõi1.9K Người theo dõi
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Timothy Saunders
Timothy Saunders@TimESaunders·
NUS has moved all of its undergrad recruitment online. As part of this, I spent 3 hours filming on Wednesday for this 2 minute video - but the end result is really pleasing. Definitely the most professional looking thing I've done for work! m.youtube.com/watch?v=cCwcDJ…
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Robert Cross
Robert Cross@_robx·
 Out now on BiorXiv, doi.org/10.1101/2024.0… is about the eduWOSM, our advanced optical microscope for educational and resource-limited settings. $9K build cost, compact, open source, super-stable, super-bright, super-controllable, user friendly, easy-to-love, able to do this:
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Timothy Saunders
Timothy Saunders@TimESaunders·
@HFSP We provide a clear estimate of the length scale of microtubule interaction in the early drosophila embryo.
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Timothy Saunders
Timothy Saunders@TimESaunders·
Many thanks to @HFSP for funding most of this work. And Jorge and Sham who did so much to bring it all together.
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Timothy Saunders
Timothy Saunders@TimESaunders·
My final (☹️) paper with Ivo Telley now out - doi.org/10.7554/eLife.… I felt the elife system worked well - first time publishing there since the changed model. Good to have different approaches- nothing is perfect.
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Timothy Saunders
Timothy Saunders@TimESaunders·
@HFSP We utilise Ivo's great explant system to make clean and quantitative measurements. This is backed up by theoretical modelling of the aster interactions with boundaries and each other.
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Timothy Saunders
Timothy Saunders@TimESaunders·
@HFSP We show that in the drosophila early embryo, microtubule asters interact through an effective pushing interaction.
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Robert Cross
Robert Cross@_robx·
The eduWOSM is our open source microscope for education and resource-limited settings. We now have a YouTube channel to explain what it is, what it can do, how it works, and how to work it youtube.com/channel/UCmOak…
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Timothy Saunders
Timothy Saunders@TimESaunders·
Really happy to see this out: journals.biologists.com/dev/article/15… We use FCS to reveal that Bicoid dynamics vary spatially across the Drosophila embryo. We demonstrate this can explain previous observations about gradient extent and time scale of formation.
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Timothy Saunders
Timothy Saunders@TimESaunders·
@scholpp_lab I think Bicoid is pretty clear - lots of direct measurements using different approaches. Of course, it's not unhindered diffusion, but alternative models do not fit with the range of experiments. (Yes, I know Bicoid is a weird morphogen)
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@scholpplab.bsky.social
@scholpplab.bsky.social@scholpp_lab·
Have we now reached a point where we can seriously question diffusion-based, long-range signalling? Is there actually any good evidence, or is everything just based on assumptions? See also: nature.com/articles/s4158…
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Pavel Tomancak
Pavel Tomancak@PavelTomancak·
Ok. This is an absolute #breakthrough and #tourdeforce by @steinaerts lab. Designing functional enhancers has been a dream of the scientific community for decades. Now AI fed with the right data cracked the cis regulatory code. Respect 🤠➡️🎩
Dresden, Germany 🇩🇪 English
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MRCDTP-IBR
MRCDTP-IBR@MRCDTP_IBR·
The deadline for applications to the MRC DTP in IBR Programme at Warwick for 2024 entry has been extended to 4th December 2023! Please click the link below to find out more about available studentships: findaphd.com/phds/program/m…
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Timothy Saunders
Timothy Saunders@TimESaunders·
@PavelTomancak @Rainmaker1973 Just moved to the Blue place - say username. Just about given up on here - the thought of my actions supporting Elon is not very edifying.
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Pavel Tomancak
Pavel Tomancak@PavelTomancak·
My Twitter feed is reduced to @Rainmaker1973 (Massimo), which is great, but... This thing is really going down.
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Jennifer Young
Jennifer Young@nano_jenn·
Excited to share the lab’s very first pre-print (!!) where we describe a new tunable hybrid hydrogel system and discover ECM-specific cues that regulate cardiac aging. Check it out!👇 biorxiv.org/content/10.110… Tweetorial follows... (1/8)
Jennifer Young tweet media
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