Pascal Grumbach

Happy to share our latest paper now out in Nature Communications: "Local activity alterations in individuals with autism correlate with neurotransmitter properties and ketamine-induced brain changes nature.com/articles/s4146…

JuSpace 2.0 is now released. Key changes: - New modern UI (also standalone is now available upon request) - New visualization functionalities - Added many new PET maps - Added different cell atlases github.com/juryxy/JuSpace

🚨Job Alert 🚨 I am currently looking for a postdoc for 3 years that will also closely collaborate with the team of the CRC TRR 393 Trajectories of Affective Disorders please share uni-hamburg.de/stellenangebot… @DGPs_JuMis @DGPs_Berlin @bioDGPs_DGPA

@KatFoerster @unihh @PB_UniHH Congratulations Katha 🥳

I am very excited to share that I‘ll be starting as a junior professor of child and adolescent psychotherapy in april @unihh @PB_UniHH 🚀 Stay tuned for some job ads ✨

🚨New paper in Journal of Affective Disorders highlights the prevalence of subclinical depressive symptoms in adults 50+ years, explores sociodemographic, (neuro-)psychological, somatic and medical links! Based on 1000BRAINS data @LabCaspers doi.org/10.1016/j.jad.…

Mit welchen Neurotransmitter-Systemen sind funktionelle 🧠-Veränderungen bei Autismus ko-lokalisiert? Wie hängen diese mit den Effekten durch Ketamin zusammen? Kommt gerne zu meiner Postervorstellung am Mittwoch von 15:30-17:00 Uhr auf dem #DGPPN Kongress!

Now out in Signal Transduction and Therapy our comment on the manuscript by Lynch et al recently published in @Nature on the expansion of the salience network in depression nature.com/articles/s4139… @INM7_ISN @LeonDLotter

Autism is associated with altered communication: evidence comes from self-reports or observations in artificial settings. We provide evidence for altered communication patterns in daily life in people with autism using smartphone-based passive monitoring: researchsquare.com/article/rs-491…

New preprint! Functional 🧠 alterations in ASD co-localize with glutamatergic and GABAergic neurotransmission and correlate with functional changes induced by ketamine. New in-vivo evidence for E/I alterations underlying ASD! @DukartJuergen @INM7_ISN @leoschilbach @sofievalk

Now out in Nature communications our article on "Regional patterns of human cortex development correlate with underlying neurobiology" integrating neurobiological brain atlases with normative modeling and population neuroimaging across lifespan nature.com/articles/s4146…

Postdoc-position available 📢 The Multiscale Neurodevelopment Lab led by Casey Paquola is hiring ! Exciting position in an exciting environment blending neuroscience and machine-learning Learn more: multiscale-neurodevelopment.github.io

🚨 Just published! Our special issue on #PrecisionPsychiatry in Biological Psychiatry is now available. Explore the latest in personalized mental health care and groundbreaking research! 🧠 👉sciencedirect.com/journal/biolog… #MentalHealth #Research #Psychiatry

1/2 Very excited to announce another PhD position in our Predictive Psychiatry group at University Hospital Frankfurt! 🧠 Help us investigate the symptom-specific neurobiology of mental disorders and cognitive dysfunction using MRI and neurostimulation. Your profile:

Antidepressant Mechanisms of Exercise 🏃🏾🚀 1. Enhances Dopamine Transmission and Neural Reward Circuitry 2. Augments Effort Exertion and Mitigates Anhedonia 3. Improves Cognitive Control Enhances attention, memory, and executive function. 4. Anti-Inflammatory Effects 👉Exercise has a net anti-inflammatory effect 👉Muscle contractions during exercise release myokines, which coordinate anti-inflammatory responses. 👉Exercise reduces adipose tissue inflammation by decreasing adipocyte size and visceral fat. 👉Reduced oxidative stress Paper 👉 nature.com/articles/s4139…

Received a travel grant for the meeting of German society for brain stimulation in psychiatry #DGHP Talked about structural connectivity alterations after multimodal in-patient treatment in severe MDD #ECT Looking forward to publishing the results together with @JonathanRepple!

Problems in interpreting your brain maps or interested in exploring biologically interpretable markers derived from imaging? Meet me at #OHBM2024 poster 2265 on our new Python toolbox, *NiSpace*, implementing spatial colocalization analyses in all kind of analysis settings! ⬇️

Happy to announce our latest paper out on Nat Medicine, where we use a small set of rest and task fMRI features to cluster participants w. anxiety/depression and relate these clusters to symptoms, behavior and treatment response! nature.com/articles/s4159…

🧠 PhD-Stelle im DYNAMIC-Konsortium in Frankfurt zu vergeben 🔍 Erforsche und personalisiere TMS als antidepressive Therapie 🔬 Analysiere Gehirn- und Symptomnetzwerke vor, während & nach der Behandlung. 🚀 Bewirb dich jetzt: lnkd.in/ekHEwGMj #NetworkAnalysis #Depression

📢 Looking for a postdoc to work on - building fully reproducible QC-pipelines for large scale MRI data - designing #machinelearning models for dataset comparison & harmonization This is a unique opportunity: - Great environment - world-class resources - lots of flexibility

Now out in @eLife our study in collaboration with @MPI_CBS demonstrating that resting state alterations in the behavioral variant frontotemporal dementia co-localize with monoaminergic and GABAergic neurotransmitter distributions. @INM7_ISN @leoschilbach