G-INCs Lab

Celebrating our CIHR grants ⁦@MCoteLab⁩. Looking forward to have great research stories coming out of our labs in next five years and more.

Congrats to all authors, and this work is supported @kidneycanada @NSERC_CRSNG @CIHR_IRSC @uOttawaMed

Acute kidney injury (AKI) can often lead to chronic kidney disease, and current treatment options are limited. Our NPs efficiently delivered miR to kidney cells and protected them against injury in in vitro models, highlighting the potential for AKI treatment.

Happy to share our recent collaborative work with Prof. Kevin Burns, showing a nanotherapeutic strategy for AKI treatment. We developed NPs containing miR486-5p and showed its protective effects in vitro pubs.rsc.org/en/content/art…

@warangal_nit @uOttawaMed @IndiaDST @NSERC_CRSNG @CIHR_IRSC

In our recent collaborative work between my PhD labmate, Prof. Raghu Chitta and our PhD advisor, Francis D'Souza, we developed a water-soluble probe with excellent PEnT properties. Our preliminary work shows the detection of fibrils in CSF mimicking fluids

Can we detect Amyloid fibrils via Photo-induced energy transfer-based fluorescent probes? aces.onlinelibrary.wiley.com/doi/10.1002/as…

Dr. Suresh Gadde’s G-INCs Lab is at the forefront of developing nano-sized tools for drug delivery. Now, his team has gone one step further by equipping these same delivery agents with built-in bioactivity. 💡 “Our proof-of-concept study might be the first one to show that particles can do more than just deliver and can contribute to treatment,” says Dr. Gadde, assistant professor at @uOttawaMed. “It’s more like we are arming them.” 🧬Such a concept could have significant implications for drug development, including leading to more targeted, personalized treatments for complex illnesses such as cancer and cardiovascular diseases. Learn more 👉uottawa.ca/faculty-medici… @uottawa #Nanomedicine #Nanomedecine #Innovation #MedicalResearch #RechercheMedicale

This work is led by our talented postdoc Shireesha. @uOttawaMed @NRC_CNRC @NSERC_CRSNG @OttawaCmm @OISB_IBSO @uOttawaCI3

Since millions of particles are injected to deliver each dose, we thought it would be good if they could do more than deliver the therapeutic agents. pubs.acs.org/doi/10.1021/ac…

Congratulations to Simon Brascoupe, OAG Special Advisor, on receiving an honorary doctorate from @uOttawa!

Nanoparticles are advancing DNA and RNA therapeutics, improving stability and efficiency. With our upcoming journal, ACS Nano Medicine, researchers have a new home for their groundbreaking discoveries. 🔗 Read our curated Collection 👉 go.acs.org/cFr

We're proud of our two @UNTChemistry colleagues who received major awards at the 2025 UNT Salute to Faculty Excellence: Francis D'Souza - Eminent Faculty Award, and @shengqianma - University Distinguished Research Professor

Congratulations to Dr. Kevin Burns, professor at @uOttawaMed, has been awarded the #KingCharlesIIICoronation Medal in recognition of his exemplary contributions in the field of nephrology and kidney research. 👏 🔗 canada.ca/en/department-… @GGCanada

The Department of Chemistry of National Institute of Technology Warangal has inaugurated a 8-day workshop on “Nanotheranostics: From Basic Principles to Clinical Utility” .Prof. Suresh Gadde, University of Ottawa, Canada in the domain of nanomedicine is the expert speaker. #nitw

New from @G_IncsLab at @OISB_IBSO: pubs.acs.org/doi/10.1021/ac…

🌟 Des recherches révolutionnaires co-dirigées par le Dr Suresh Gadde de @uOttawaMed montrent que la combinaison des thérapies à base d’#ARNmessager et d’#interférenceARN pourrait transformer les traitements contre le #Cancer et les #MaladiesCardiovasculaires ! 🧬 En savoir plus : uottawa.ca/faculte-medeci… @SuriSpurs @OttawaCmm @uOttawa @uOttawaResearch  #ResearchResearch

This work is co-led by our talented trainees, Shireesha and Sara. @uOttawaMed @uOttawaBMI @OttawaCmm @MCoteLab @NRC_CNRC @OISB_IBSO @uOttawaCI3 @CIHR_IRSC

Can we differentially manipulate multiple gene/protein expressions? In this collaborative work Dr. Wang, we showed simultaneous restoration and silencing of two different Gene/Protein expressions in vivo in TNBC models using NPs containing mRNA and siRNA pubs.acs.org/doi/10.1021/ac…

Thanks a lot for visiting us.

Looking forward to visiting @uOttawaMed to share some of the research happening in our group. Thank you @SuriSpurs @G_IncsLab for the invitation!