The Rog Lab

The last of my graduate work with @DianaLibuda is out in @eLife! We show that BRCA1 and SMC-5/6 regulate DNA break repair pathway engagement in C. elegans meiosis, but are not required for intersister repair. A fun "crossover" collab with @TheRogLab! elifesciences.org/articles/80687

In their Review, Iván Olaya, @smburgessucd @BurgessLab and Ofer Rog @TheRogLab discuss the formation and resolution of meiotic chromosome entanglements and interlocks. journals.biologists.com/jcs/article/13…

We are pleased to report the publication of our review on the formation and resolution of meiotic chromosome entanglements and interlocks. It was a pleasure to work with Ofer Rog @TheRogLab and Iván Olaya @meiocyte_Ivan on this project. journals.biologists.com/jcs/article-ab…

TOMORROW, 1pm EDT📣 Ofer Rog of @UoUBiology will cover 2 unpublished stories from his lab on unexpected de-mixing of sister chromatids during meiotic prophase & a 🆕 genomic technique to characterize large-scale chromatin organization. Register: bit.ly/4bi0E4v @TheRogLab

🗓️ July 11, 1pm EDT: bit.ly/4bi0E4v Ofer Rog of @UoUBiology will cover 2 unpublished stories from his lab on the unexpected de-mixing of sister chromatids during meiotic prophase & a 🆕 genomic technique to characterize large-scale chromatin organization. @TheRogLab

We’d love to get feedback and suggestions. Kudos to Kewei, an amazing grad student who developed CheC-PLS over the last 5 years; to Chloe and @lexy_von_diez (now with her own lab, new-car-smell and all, at UMinnesota); and to @LisaKursel and a super-talented undergrad, Kaan.

So Skp1 has been moonlighting for >100 million years. Which adds a new twist to the SC paradox: how does a highly conserved protein (Skp1) maintains intimate interaction with quickly diverging proteins in a way that does not leave a clear evolutionary mark in their sequence?

Three (3) new pre-prints from the lab! Very proud of this work that spans approaches and model organisms, and highlights the many approaches the lab undertakes.