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Lucia Strader
Lucia Strader@LabStrader·
Biomolecular condensates organize cellular contents. Most studies focus on passive phase separation, driven by salt, pH, or temperature. But what if intracellular movement also matters? science.org/doi/10.1126/sc… Here, we explore motility-induced condensation in a cellular context.
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Lucia Strader
Lucia Strader@LabStrader·
In plants, the transcription factors ARF7 & ARF19 control gene expression in response to auxin. But these ARFs can be sequestered into cytoplasmic condensates—shutting down their activity. Why do these condensates form only in the cytoplasm?
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Monika Chodasiewicz
Monika Chodasiewicz@StressGranuleMC·
@LabStrader Great to see more mechanistic explanation into actin-dependent regulation of condensate behaviour! Congratulations to all authors, beautiful work 👌
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Raffaele Di Giacomo, PhD
Intriguing topic, Lucia! The idea that intracellular movement could influence biomolecular condensates broadens the scope beyond passive mechanisms. This leads me to wonder how cellular processes like cytoskeletal dynamics might play a role? It could be a game-changer in understanding cellular organization. For an in-depth dive into similar biomedical queries and reviews, I highly recommend checking out sciqst.com, which serves as a comprehensive platform for biomedical exploration. #CellBiology #Medicine
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