Alex Detappe

ADC are IV-dominant. Biology permits SC. Engineering blocks it. Our J Controlled Release perspective details what's needed: conjugation chemistry, high-conc formulations (>100 mg/mL), biomaterials, devices. sciencedirect.com/science/articl… @ERC_Research @laliguecancer @GustaveRoussy

Thanks a lot for inviting me! It was a blast meeting you all!

@julnicolas @CNRSIdFSud @CNRS @CNRSchimie @UnivParisSaclay @umr8612 @ERC_Research @Pharma_UPSaclay Love it! Congrats !

☝️Developing nanoscale drug delivery systems is important, but their dosing regimens are key 🥳Thrilled to see our work titled ‘Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice’ published in Adv Healthc Mater! advanced.onlinelibrary.wiley.com/doi/10.1002/ad…

Dynamic precision cancer nanomedicine bit.ly/4prqWI5

New in @NatRevBioeng w/ @FAndreMD : No targeted nanomedicines approved despite preclinical tumor accumulation. Our thesis: It's not poor delivery, it's static formulations in a dynamic disease. Time to test adaptive nanomedicine. Thanks @ChristineHorejs! rdcu.be/eQ6J5

@laliguecancer @ERC_Research @unistra @CGFL_Dijon #InstitutMedicamentStrasbourg #ICANS

Big congrats to Dr. Sebastian and our amazing collaborators for making this happen 🙌 If you’re interested in smarter radioenhancers and “see & treat” oncology, check out the paper: 🔗 pubmed.ncbi.nlm.nih.gov/41259368/

Our latest paper in @ACSNano is out! 🤩 We built tiny peptide-based “delivery vehicles” that bring heavy metals (Gd, Bi, Hf) to tumors so we can fairly compare how well each one boosts external radiotherapy and radioligand therapies.

@rvdmnanomeds @EUeic @WillemNANO @BioTRIPBV @AMakriPistikou @twan_lammers @radboudumc @TUeindhoven1 @VUBrussel @RWTH Congrats!! this is huge! Well done!

🥳 Super stoked that our program 🏎️ DRIVIN' CAR has received €3M @EUeic Pathfinder funding to develop our #apolipoprotein #nanoparticle platform for in vivo #CAR cell therapy! Can't wait for @WillemNANO and my group to work with the awesome folks and teams below 👇

@julnicolas J'ai des bureaux et paillasses dispos pas trop loin si tu veux re localiser 😇

Ça serait bien que cette période de télétravail forcé ne s’éternise pas trop car je suis en train de vider mes stocks à vitesse grand V 🍫

Thank you @le_Parisien @leparisien_94 for being with us at @GustaveRoussy on this special day. It’s not just about a new building, but about pushing research forward and giving more hope to patients.

📰 « Les patients attendent beaucoup de nous » : face au cancer, @GustaveRoussy offre un écrin tout neuf à ses chercheurs. Les Prs Fabrice @barlesi et @FAndreMD rappellent l’ambition de l’institut dans @le_Parisien ⤵ leparisien.fr/val-de-marne-9…

#IMS25 In my mind, this will be the slayer of ASCT more than any other #MMsm regimen... Excellent Tec-DVR & Tec-DR data [1x weekly Velcade & lots of IVIG 👏] in NDMM from MajesTEC-5 @RaabMarc 100% ORR, 100% MRD neg across the board. This is what we hope for with induction!

📰 De nouveaux laboratoires de #recherche pour @GustaveRoussy sur le Campus Grand Parc. Sept équipes de chercheurs de Gustave Roussy s’installent dans des locaux de 850 m² d’un nouveau bâtiment, le LAB 116/Perelis. Actuellement en plein développement autour de l’Institut, le Campus Grand Parc est amené à devenir le plus vaste ensemble entièrement dédié à la #cancérologie en Europe 🇪🇺. En savoir plus ➡ gustaveroussy.fr/fr/news-de-nou…

Inspiring week at #CRS2025 - my first @CRSScience conference, and I truly loved it! Grateful for the vibrant community, meaningful discussions, and new collaborations taking shape. Special thanks to the @CRS_FG_NANO for the award - honored and motivated!

The lab was awarded its first ever ANR funding - congrats to @HarleppS for leading this initiative ☺️ !

Using ‘supporting molecules’ (SUMs) to improve mRNA LNP therapies bit.ly/44EGkYP

1/ be nice 2/ be real 3/ be unique 4/ be critical and self critical 5/ read a lot 6/ talk to many people 7/ ask tough question 8/ think hard 9/ work hard 10/ work with people you like You said it all, @twan_lammers - you very well deserved the YSC award 👏