Chang Jiang 姜畅

Congratulations Yuyang! 👏

Every PI

New! Online now: Tissue and CD4 T cell subset dependence on the amino acid transporter SLC38A1 dlvr.it/TRfVjQ

@bradylabupenn @ASBMB Congratulations, Donita!

Grateful to @ASBMB for this extraordinary honor and to the colleagues who nominated me. This recognition means a great deal because it affirms something I believe deeply: talent is universal, but access is not.

1/3 Thrilled to see our paper led by Kirandeep Deol is out! We used CRISPR screens to uncover regulators of the ferroptosis suppressor FSP1. key discovery: vitamin B2 metabolism stabilizes FSP1 via FAD, revealing a new way vitamins regulate ferroptosis. nature.com/articles/s4159…

Neutrophil-mediated anti-tumoral effects of caloric restriction dlvr.it/TRQxhh

The dual role of the pentose phosphate pathway in homeostasis and regeneration dlvr.it/TRPpfb

We are excited to announce that our recent collaborative paper, led by the superstar duo Rebekah Nicholson and Luis Cedeño-Rosario, which identified how ceramides alter mitochondrial structure and function after acute kidney injury was selected to participate in #STATMadness! Check it the press release here: tinyurl.com/y2pk2tcy Vote daily at: t.co/I4wfZE7yP5

Online Now: Tumor-restraining fibroblasts emerge after chemotherapy specifically in responders dlvr.it/TRLHsS

@lab_gomes Congratulations!🍾🎊🎈

So proud of Joanne Tejero, the first Gomes Lab student graduating 🎉🥳 🎓 #proudPI

New! Online now: Purified diets enable experimental rigor through compositional control in animal research dlvr.it/TRCCdL

Out today in @cellcellpress new work from the lab led by Abby Xie and @jules_stef asks, when and why do cells use the TCA cycle?

Online Now: Aspartate availability drives differential engagement of the malate-aspartate shuttle dlvr.it/TRB143

New! Online now: Lack of PCK1 in hepatic stellate cells causes liver fibrosis by fueling tricarboxylic acid cycle and increasing glycolysis dlvr.it/TR6mSR

RESEARCH | R Sun, X Liang et al (Shandong Uni, CN) Psychological #stress-mediated dysregulation of catecholamine signaling rewires #hepatic kynurenine pathway which impairs liver CD8+ #Tcell function & promotes liver #cancer progression. nature.com/articles/s4225…

Lung cancers in never smokers (LCINS) @trendscancer commentary by @CharlesSwanton & colleagues, from risk factors, to screening modalities to prevention strategies. cell.com/trends/cancer/…

Multimodal spatial-omics reveal co-evolution of alveolar progenitors and proinflammatory niches in progression of lung precursor lesions dlvr.it/TQsDXl

Excited for the NAMs and Cancer Engineering Summit next week!

Join us for a day of collaboration and innovation as we explore the rapidly evolving field of New Approach Methodologies (NAMs). In association with the Cancer Engineering Summit, we are bringing together leaders from academia, industry and policy to discuss the latest developments and potential benefits of NAMs—including improved predictive validity, reduced animal use, cost efficiencies and faster translation to clinical applications. Register now: bit.ly/43IwPrQ

Now online! Hallmarks of cancer—Then and now, and beyond dlvr.it/TQjSM2