Hulk

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@bryan_johnson My source for all the peps 💪 houseofcompounds.com

Just spent over an hour with my clinical team debating which growth hormone peptide protocol to run. Still torn. Wanted to share the thinking and get your take. The goal: Increase GH and IGF-1 to support anabolism, recovery, and sleep, but also test a specific stacking hypothesis. Tirzepatide (GLP-1/GIP agonist) can elevate resting heart rate, disrupt sleep, and suppress appetite aggressively. CJC-1295 (GHRH analog) can worsen insulin resistance. The bet is that combining them cancels each other's downsides: CJC-1295's slow-wave sleep enhancement offsets tirzepatide's sleep disruption, while tirzepatide's insulin-sensitizing effects counteract CJC-1295's insulin resistance. Best of both worlds — or at least, that's the hypothesis we're testing. The two candidates: CJC-1295 with DAC: the long acting version. One injection per week, stays active for 6–8 days. This is what was used in the actual clinical trials. Raises GH 2–10x and IGF-1 1.5–3x from a single dose. Preserves GH pulsatility even under continuous stimulation. The tradeoff: if you get side effects, you're committed for a week. Harder to titrate. CJC-1295 without DAC + ipamorelin: the short-acting version paired with a selective ghrelin receptor agonist. Daily injections, pre-bed, clears in 30 minutes. Ipamorelin adds a second axis of GH release, pulse frequency via the ghrelin pathway, on top of the amplitude boost from CJC. No cortisol or prolactin elevation. This is what most clinicians prescribe and most of the peptide community uses. The tradeoff: less clinical trial data, daily injections, more anecdotal evidence base. What we're considering: Start with DAC at half dose 2.4 mg, then if well tolerated escalate 4.8 mg, weekly injection. If side effects aren't tolerable, switch to no-DAC + ipamorelin (100 mcg then 200-300 mcg daily, before bedtime). Or, Run both head to head. 2 weeks DAC, 2 weeks no-DAC + ipamorelin and compare. Tracking: GH, IGF-1, Cortisol, CGM, real time core body temperature, RHR, overnight HRV (rMSSD), IGF-1, HOMA-IR, sleep architecture, subjective recovery. The purist in us says stick with DAC; that's where the published data lives. Yet the pragmatist says no-DAC + ipamorelin is what thousands of people actually use, and testing it generates more socially relevant data.

Tim Cook stepping down. $AAPL

I want you all to listen to this. 🔥 Have a good night everyone.

@CBOSSSSS Close to a weekly breakout. $TWLO

@HulkCapital Twlo also on radar hulk

$ROKU coming out of a 3+ year long base!

The weekly chart on Bitcoin is shaping up nicely. Momentum suggests a move back toward $80K+.

OMG $CAR

👇

Market Oscillator are near nose bleed levels. They don't stay up here long. $NAMO

$MU doesn’t need a full pullback to the 20-day. I’d be perfectly fine with a dip to 430.

@TheNightmanSD Yes, not bad.

@HulkCapital hulk logo on sofi daily?

$KODK still in the early innings here. 5yr base breakout.

$TH Flag Breakout

Hmm..

Trump Administration to Begin Refunding $166 Billion in Tariffs - NYT

So talks are going smoothly.. 👍😃

Anthropic’s CEO says AI could spark a major employment crisis over the next 1 to 5 years.

It’s called political connections.

Let’s see.. $SPY