Peng Jiang Lab

@KaurTejbeer Thank you, Tejbeer!

@LabJiang Looking forward to reading it. Always exciting stuff.

Can grafted microglia be harnessed for neuronal replacement? Motivated by their unique properties for cell-based therapies, we explored the direct conversion of human microglia into neurons. Excited to share our new study on bioRxiv.

Chimeric brain models: Unlocking insights into human neural development, aging, diseases, and cell therapies: Neuron cell.com/neuron/fulltex…

All models have limitations. Animal models are indispensable for neuroscience research. Meanwhile, chimeric brain models provide opportunities to study human neural cells with advanced maturation and functional integration in an in vivo brain environment cell.com/cell-metabolis…

Aβ plaques induce local pre-synaptic toxicity in human iPSC-derived ne... sciencedirect.com/science/articl…

In this study, we developed a series of new chimeric brain models by combining different transgenic mouse lines with co-transplantation of human microglia and neural cells, enabling in vivo studies of human neuro–glia and glia–glia interactions.

Thrilled to share our new study published in @CellReports! 🎉 Led by @jin_mengmeng, @ZiyuanMa5, and Haiwei Zhang. Grateful for a wonderful collaboration with Dr. Steve Goldman, a pioneer in chimeric brain models and glial biology. cell.com/cell-reports/f…

Thank you for highlighting our work!

@LingyongLiLab Thank you, Lingyong!

@LabJiang @NatureNeuro @jin_mengmeng Great congratulations!!

An idea we started in 2019 is now published in @NatureNeuro! Excited to share our new study: rdcu.be/eRvdA Congrats to Mengmeng Jin @jin_mengmeng and our team! Heartfelt thanks to all collaborators for their support, and to the reviewers for their insightful comments!

@LongJun_Wu Thank you so much, Longjun!

@LabJiang @NatureNeuro @jin_mengmeng Exciting work! Many congrats, Peng!

@HarryFu80763542 Thank you very much, Harry!

@LabJiang @NatureNeuro @jin_mengmeng Congrats Peng and the team! Excellent work!!

A myeloid trisomy 21-associated gene variant is protective from Alzheimer’s disease @NatureNeuro nature.com/articles/s4159…

Explore our new study here 👇, and Happy Thanksgiving to all! Author’s link: rdcu.be/eRvdA Rutgers Today article @RutgersU_News @RutgersSAS @RutgersU: rutgers.edu/news/inspired-…

Human microglia differentially respond to β‐amyloid, tau, and combined Alzheimer's disease pathologies in vivo alz-journals.onlinelibrary.wiley.com/doi/10.1002/al… @alzdemjournals

Returned to this platform to amplify this beautiful work! Well done Sonia and all! A major step forward and key experimental insights for how we advance this for many diseases.

We are pleased to share our newest publication from the @BlurtonJonesLab, "CSF1R inhibitor-resistant model for CNS-wide microglia replacement strategies" sciencedirect.com/science/articl…

We are excited to announce the 3rd ASCN Symposium, Jan 28-30, 2026 in Houston! Featuring a keynote by Dr Hongkui Zeng @HongkuiZeng @AllenInstitute and 10 exciting sessions. Join us for cutting-edge talks, trainee award & networking! Register at sfnchinese.org

This study was co-led by our talented undergraduate student, Kushal, whose curiosity and dedication inspired us all. Sadly, he passed away before its publication — this work stands as a tribute to his passion for science.

Excited to share our new @STARProtocols paper! We present step-by-step methods for purifying primitive neural progenitors by fractional passaging to generate astroglia-enriched cerebral organoids Read here 👉: sciencedirect.com/science/articl…