Sourav Kumar Das

Phage lovers! Introducing Phage-Induced Immunity (PHI-II). This discovery suggests that some phage can not only treat an existing infection (well known) but they can also immunize to prevent a future infection (new finding). Read about the adventure here: pnas.org/doi/10.1073/pn…

The new phage therapy regs mean no licensed products, strict GMP rules, and high costs limiting access, slowing innovation, and deterring investment. Patients rely on ad hoc imports and “last resort” use. Time to break the impasse and unlock phage potential! #AMR #Phagetherapy

🚨New publication🚨 We show that K. Pneumoniae bacteriophages can be incorporated into alginate to create an antibiofilm matrix effective against clinical K. pneumoniae strains academic.oup.com/jambio/article…

@phagedirectory @liyuping927 @UCSF Great study. As we still need to know many things about ancient and advanced immunity of bacteria. Cost of research for discovering right phages and making recombinant phages can only be used as an immediate solution but definitely not for prolonged therapeutics. #phage

.@liyuping927 (@UCSF) and colleagues published a new paper on a bacterial immune system targeting jumbo #phages, showing it disrupts an early phage infection compartment to block replication. buff.ly/GcJz6oO

nature.com/articles/d4158… New antibiotic that kills drug-resistant bacteria discovered in technician’s garden The molecule targets bacteria in a way that other drugs don’t.

@MotherOfPhage @phagedirectory @latrobe You can do a TFF buffer exchange I will say more than 50 time the volume with final buffer of the sample followed by reconcentrating it. viva spins.

@phagedirectory @latrobe But how do you remove Triton X?

Siti Adil (@Latrobe) and colleagues published a new #phage purification methods comparison paper, showing Triton X-100 was most effective for #endotoxin removal and phage recovery compared to CsCl ultracentrifugation and endotoxin removal resin columns. buff.ly/8ys6YTi

@ErikBakkeren Thanks Erik, I will contact Prof. Foster.

@SouravKumarAMR I'd suggest you get in touch with Kevin directly for details!

My postdoc mentor Kevin Foster is hiring postdocs! Apply to join an exciting research group looking at ecology and evolution of the gut microbiome. Kevin is a fantastic mentor and I can completely recommend: fosterlab.uk/vacancies

Well done to @Het_Gajjar37 for presenting his contribution to our phage bacteriocin story at @VoM_UK

Coffee consumption is associated with the presence and abundance of a specific member of the human gut microbiome, Lawsonibacter asaccharolyticus, and changes to the plasma metabolome, according to a paper in @NatureMicrobiol. go.nature.com/4i3gqUI

We've got scores on the doors for our BUZZ wire game 👀 Check out the prizes on offer👇 🥇 DNA socks @SouravKumarAMR 🥈 Lab beaker candle @WinterJody 🥉 Microscope key ring @HobleyLab Make sure you drop by and grab some stickers too 😍 #EastMidsAMR #AMR #WAAW24

Beautiful day at @NottmTrentUni though it’s just 4°C. 🥶

PhD studentship with @MarthaClokie and me at @Leicester_Phage . Part of larger CF Trust Hub led by @JoJofoth Selection of bacteriophages for therapeutic use in cystic fibrosis-associated Pseudomonas aeruginosa infections at University of Leicester on FindAPhD.com

Check our latest preprint! We've doubled the number of known weberviruses (phages of Klebsiella) and taken a bit of a deep dive into their genomes to better characterise the genus.

When experiments don’t work... build a phage costume! 🎃 Happy PHAGEOWEEN!!! 👻🧬#Teamwork

Check out @npjAMR new review on how Gram-negative bacteria escape Bdellovibrio predation!🦠☠️ @dp_negus @SouravKumarAMR (1/5) nature.com/articles/s4425…

#TranslationalResearch #PhageTherapy #AntibioticResistance #InfectiousDiseases #Microbiology #Biotech #MedicalInnovation #Biofilms #Antimicrobial #PrecisionMedicine #SyntheticBiology #FutureOfMedicine #HealthcareInnovation Something on my inotes….

Our review on 'Phage Diversity in One Health' has been published in Essays in Biochemistry 🥳doi.org/10.1042/EBC202…. A big thanks to all co-authors for their contributions @EvelienAdri @Revathykri @RyanCookAMR ✨ @PPPublishing @micronorwich

The NTU World AMR Awareness Week (18-24 Nov 2024) student competition has been launched by @WinterJody. Students around the world: submit a short video or comic strip suitable for a broad audience, to help us raise awareness of AMR. Deadline 10 Nov (midnight GMT).