Vietnam Era Twin Study of Aging

🚨NEW DATA RELEASE🚨 Data from VETSA waves 1-3 is now available for public download from NACDA! This includes cognitive, health, psychosocial and demographic info from our nationwide twin cohort. icpsr.umich.edu/web/ICPSR/stud…

Visit our website below for more information. psychiatry.ucsd.edu/research/progr…

Future releases will include wave 4 data and derived MRI variables. Please do not hesitate to reach out directly with questions or for more information. Additional data such as raw MRI images in BIDS format and composite variables are also available upon direct request.

🚨NEW DATA RELEASE🚨 Data from VETSA waves 1-3 is now available for public download from NACDA! This includes cognitive, health, psychosocial and demographic info from our nationwide twin cohort. icpsr.umich.edu/web/ICPSR/stud…

First poster done at #AAIC2025. 😊 Grateful to my lab @VETSATwinStudy, mentors (@elman_jeremy @PanizzonLab), and my funding from @NIHAging for being able to do this research.

Excited to share my new study with the @VETSATwinStudy team (@elman_jeremy @PanizzonLab) published in #JINS showing that moderate-to-severe chronic pain and opioid use are independently related to risk of mild cognitive impairment. tinyurl.com/y88k5z4j @UCSanDiego

Our new paper on cognitive resilience against Alzheimer’s pathology is out now! We explore common conceptual issues (i.e., differentiating resilience vs. low risk) and identify cortical regions that confer resilience against p-tau/cortical thinning 🧠 onlinelibrary.wiley.com/doi/full/10.10…

New article led by @cfn_peace and Shu-Ju Lin describing a novel parcellation of abnormal white matter w/ 5 distinct regions. Twin models identified common & unique genetic & environmental influences that may reflect variable underlying etiologies. Link 👇

Cool new work from @TylerBellPhD et al (inc Drs Franz, @KRThomasPhD Williams @LisaEylerPhD Lerman @cfn_peace Panizzon @elman_jeremy Kremen) Elevated CRP in Older Men With Chronic #Pain: Association With Plasma #Amyloid Levels and #Hippocampal Volume academic.oup.com/biomedgerontol…

First official tweet on a new paper in BP:CNNI with @VETSATwinStudy @elman_jeremy: Early Cortical Microstructural Changes in Aging Are Linked to Vulnerability to Alzheimer’s Disease Pathology sciencedirect.com/science/articl… Thread to follow!

#ICYMI...NEW RESEARCH: The Association between Exposure to Fine Particulate Matter and MRI-Assessed Locus Coeruleus Integrity in the Vietnam Era Twin Study of Aging (VETSA) ➡️ buff.ly/4cZ6xE6 @elman_jeremy @VETSATwinStudy @UCSDMedSchool @USC @UW

Trailblazing study in Elsevier’s BP:CNNI shows the spatial pattern of pathological changes in the brain can help identify #dementia risk decades before it occurs spkl.io/60104hEme @BiologicalPsyc1 @SOBP @Els_Psychiatry @VETSATwinStudy #VETSA

So appreciative to be able to be able to study chronic pain and dementia risk thanks to @NIHAging and to present this work with excellent colleagues at #AAIC2024 @elman_jeremy @VETSATwinStudy @PanizzonLab @rushalzheimers

NEW: Ambient air pollution is associated with risk of Alzheimer’s disease & related dementias. Puckett et al. now report evidence of a potential pathway: damage to the locus coeruleus caused by PM2.5 ➡️ buff.ly/4cZ6xE6 @elman_jeremy @VETSATwinStudy @UCSDMedSchool @USC @UW

New #VETSA paper alert!

In early old age men without dementia, plasma NfL levels do not seem to be sensitive to individual differences in most cognitive domains or neuroimaging measures of gray and white matter.

The association between plasma NfL and processing speed was primarily observed in individuals with mild cognitive impairment (MCI) and not in cognitively unimpaired (CU) individuals.

In this latest paper on plasma neurofilament light chain (NFL) from the #VETSA team led by Tang et al. (alzres.biomedcentral.com/articles/10.11…) we examined the association of plasma NFL with five cognitive domains as well as neuroimaging measures of gray and white matter. 🧵1/n