Serini Lab

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Serini Lab

Serini Lab

@adhynamic

Our lab tries to grasp the molecular mechanisms by which cells adhere to and move through the body environment in cancer, vascular and rare genetic diseases

Candiolo Cancer Institute, IT انضم Mart 2013
823 يتبع1.6K المتابعون
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Serini Lab
Serini Lab@adhynamic·
Glad to share our last manuscript on a luminescent sensor we created to unveil novel potentially actionable regulators of β1 integrin activation in vascular endothelial cells and angiogenesis. Great collab w/ Jieqing Zhu Lab @VersitiResearch @ZanivanLab doi.org/10.1016/j.celr…
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Cell Reports
Cell Reports@CellReports·
Mechanobiological mechanism of cyclic stretch-induced cell columnarization dlvr.it/TKdwss
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The EMBO Journal
The EMBO Journal@embojournal·
Local weakening of cell-extracellular matrix adhesion triggers basal epithelial tissue folding Andrea Valencia-Expósito, María Martín-Bermudo et al embopress.org/doi/full/10.10…
The EMBO Journal tweet media
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Serini Lab
Serini Lab@adhynamic·
Glad to share our last manuscript on a luminescent sensor we created to unveil novel potentially actionable regulators of β1 integrin activation in vascular endothelial cells and angiogenesis. Great collab w/ Jieqing Zhu Lab @VersitiResearch @ZanivanLab doi.org/10.1016/j.celr…
Serini Lab tweet media
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Serini Lab أُعيد تغريده
Ben Goult
Ben Goult@bengoult·
September issue of @JCellBiol also contains our new paper on TLNRD1 (talin rod domain containing 1) protein and its role in the Cerebral Cavernous Malformation complex. rupress.org/jcb/article/22… @guijacquemet @LivUniISMIB @biokent @UniTurku
Journal of Cell Biology@JCellBiol

Our September issue is out! hubs.la/Q02N4zdK0 🔬 The cover shows the heart (cardiac tube) of a 20-day old adult #Drosophila stained with phalloidin (red), while adjacent pericardial cells are marked by dorothy-GFP (green). From @gera_jayati et al (hubs.la/Q02N4zxk0)

Liverpool, England 🇬🇧 English
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Enrico Giraudo
Enrico Giraudo@GiraudoEnrico·
Our paper is now out!! Great and exciting collaborative work. Thank you all. PlexinB1 Inactivation Reprograms Immune Cells in the Tumor Microenvironment, Inhibiting Breast Cancer Growth and Metastatic Dissemination aacrjournals.org/cancerimmunolr…
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Ben Goult
Ben Goult@bengoult·
We just updated our preprint, "The structure of an Amyloid Precursor Protein/talin complex indicates a mechanical basis of Alzheimer's Disease" to include beautiful new proximity ligation data of talin and APP in neurons. 😍 @jcl_lambert @LivUniISMIB biorxiv.org/content/10.110…
Ben Goult tweet media
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Cell
Cell@CellCellPress·
Now online! Ligand binding initiates single-molecule integrin conformational activation dlvr.it/T791P4
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Cell Biology J-Club
Cell Biology J-Club@cell_club·
Rab7 deficiency induces lysosome formation from recycling endosomes leading to an increased degradation of cell surface proteins biorxiv.org/content/10.110…
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Paolo Armando Gagliardi
Paolo Armando Gagliardi@paoloarmando83·
Check out our latest review in which we discuss the recent exciting discoveries on single-cell and collective ERK signaling dynamics!
PertzLab@PertzL

Check out our recent review on the ever-evolving #MAPK/#ERK signaling dynamics. It never ceases to amaze me how one of the most studied signaling pathways continues to deliver new surprises. Thanks to @paoloarmando83 for writing this with me. sciencedirect.com/science/articl…

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eriksahailab
eriksahailab@eriksahailab·
Very pleased to share our latest preprint on MAPK dynamics and cell fate decisions in lung cancer biorxiv.org/content/10.110… . Does EGFR mutation mean MAPK is always on? NO, it shows dramatic pulses👇1/4
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Ishier Raote
Ishier Raote@ishier_raote·
Our latest paper! A promising avenue for therapeutic intervention in fibroses, characterized by excessive ECM production, via targeted inhibition of TANGO1-mediated ER export. TANGO1 inhibitors reduce collagen secretion and limit tissue scarring nature.com/articles/s4146…
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Sara Zanivan
Sara Zanivan@ZanivanLab·
Thrilled to see our latest work “Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function” led by Alice Santi and @emilyjkay1 on the cover of @scisignal. Beautiful images by @BairBeatson Paper here 👇🏻 science.org/doi/10.1126/sc…
Sara Zanivan tweet media
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Johanna Ivaska
Johanna Ivaska@johannaivaska·
Interested in a Post-doc @IvaskaLab @BioscienceTurku working on novel anti-invasive barriers in BrCa - cutting edge cell biology/imaging/HTS/clinical collaboration? Watch this space! We will be shortly opening a call a post-doc @WorldwideCancer granted 3 year funding
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اكتشف

@paoloarmando83 @VersitiResearch @ZanivanLab @JCellBiol @LivUniISMIB @biokent @UniTurku @NatureComms