Spotlight: new work from Zhao et al. (hubs.la/Q04gBKv50) establishes a direct link between PI(3)P and #actin in mitochondrial dynamics. Sneha Hegde and Marc Germain @UQTR discuss the findings: hubs.la/Q04gBDpc0
#Mitochondria #Lipids
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Journal of Cell Biology
16K posts
Journal of Cell Biology
@JCellBiol
The Journal of Cell Biology (JCB) publishes peer-reviewed research on all aspects of cellular structure and function. Est. 1955 - @RockUPress
New York, NY Katılım Eylül 2009
967 Takip Edilen54.5K Takipçiler
Williams, @KamenzLab, @SilkeHaufLab et al. @virginia_tech show that synchronous chromosome segregation does not require separase-mediated positive feedback and that slight asynchrony may be unavoidable due to stochastic effects hubs.la/Q04gCTCN0
#CellDivision #Mitosis
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Journal of Cell Biology retweetledi
Our new paper is out ! Congrats to @JBernierLatmani and the entire team!🎉🎉
Journal of Cell Biology@JCellBiol
#Eosinophils–usually linked to infection and disease–are actually helping to build the gut. New research from @PetrovaLab & @JBernierLatmani shows they reprogram fibroblasts into villus smooth muscle cells, helping shape and mature the villi postnatally. hubs.la/Q04ggV0t0
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Perspective: Seohyun Park, Fiona Fitzgerald, Yoon-Mo Yang (Hanyang University) & Katrin Karbstein (@VanderbiltU) describe problems that plague the analysis of #ribosome specialization, as well as ways to address them to guide experimentation in the field hubs.la/Q04gd0pG0
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Guerrero-Fonseca, Schnoor @cinvestav et al. provide evidence for a cellular crosstalk through which #neutrophils transfer #proteases into #endothelial cells to degrade cortactin thus facilitating breaching of the vascular #endothelium during #inflammation. hubs.la/Q04gcKHw0
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#Eosinophils–usually linked to infection and disease–are actually helping to build the gut. New research from @PetrovaLab & @JBernierLatmani shows they reprogram fibroblasts into villus smooth muscle cells, helping shape and mature the villi postnatally. hubs.la/Q04ggV0t0
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Read An interkinetic envelope surrounds chromosomes between #meiosis I and II in #Celegans oocytes rupress.org/jcb/article/22…
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“This recognition validates years of meticulous imaging and cell biology work uncovering a novel organelle critical for meiotic fidelity,” says Julien Dumont of being included in The Year in Cell Biology: 2025. Learn more about publishing in JCB. hubs.la/Q04ggQKW0
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Journal of Cell Biology retweetledi
Very happy to share our latest study out now in @JCellBiol! We describe a new way in how macrophages translate cell volume changes to sense danger and drive inflammation. Check it out here hubs.la/Q04fQS5V0
Journal of Cell Biology@JCellBiol
Cook, Green et al. @OfficialUoM show that #macrophages sense cell volume disruption as a danger signal promoting transcriptional reprogramming and inflammatory responses via type I interferon signaling. hubs.la/Q04fQS5V0 #Inflammation #CellSignaling #Immunology
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Journal of Cell Biology retweetledi
The mechanism by which macrophage cells sense danger to drive an immune response and inflammation has been elusive. A new report highlights change in cell volume as the signal @JCellBiol
rupress.org/jcb/article/22…
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Covill-Cooke, Hirashima, Kawano, Endo, Kornmann @UniofOxford and colleagues find that the ERMES #lipid-transporting complex, long-thought to be an obligate heterotetramer, can be replaced by only one component: mitochondrially tethered Mmm1. hubs.la/Q04fQRtw0
#Mitochondria
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@OfficialUoM See the accompanying press release:
📰 eurekalert.org/news-releases/…
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Cook, Green et al. @OfficialUoM show that #macrophages sense cell volume disruption as a danger signal promoting transcriptional reprogramming and inflammatory responses via type I interferon signaling. hubs.la/Q04fQS5V0
#Inflammation #CellSignaling #Immunology
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See the original paper in JCB from James R. Cook, Jack P. Green, and colleagues: rupress.org/jcb/article-lo…
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How #macrophages interpret and respond to immune danger signals remains a mystery. Researchers at the University of Manchester have found that increases in cell volume reprogram macrophage gene expression and induce #inflammation. hubs.la/Q04fHLlk0
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Das, Coronado-Chavez, Nordman et al. show that in #Drosophila, the #histone chaperone NASP indirectly affects the nuclear import and #chromatin deposition of H3. Their findings reveal a cytoplasmic function for NASP in preventing H3 aggregation in vivo. hubs.la/Q04fHbln0
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Yeh, Martin @MITBiology et al examine the #Drosophila synaptotagmin-like protein Btsz in early embryo nuclear divisions, identifying a role for regulating pseudo-cleavage furrow stability. They show that Btsz bundles #actin filament networks in vitro. hubs.la/Q04fH3vZ0
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Appalabhotla, Siesser et al. developed a system enabling light-mediated recruitment of PLC-γ1 variants to dissect mechanisms underpinning cancer-associated hyperactivity, and they show that recruitment of active PLC-γ1 robustly directs fibroblast migration hubs.la/Q04fxH1q0
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Olga D. Jarosińska, Mike Boxem et al. reveal how LGL-1 and PAC-1 team up to polarize the #Celegans embryo, providing new insight into how conserved #polarity mechanisms are adapted across species.
hubs.la/Q04fswNZ0
#CellPolarity #Genetics
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To find mating partners, #yeast cells use a default #polarity site to assemble a gradient tracking machine, which then redistributes up the pheromone gradient. Pai et al. show that GTM redistribution requires the plasma membrane lipid, phosphatidylserine. hubs.la/Q04fsnVT0
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