Julia

@da_cruzag Thank you! I think ethanol is less effective because of the solubility of the substrate, it is more soluble in methanol.

@julia_ur1 @LatinXChem @GroupGamba @OrgBiomolChem @EurJOC Nice work! Do you have any thoughts about why is ethanol considerably less effective than methanol? Do you think the pressure generated or the ammonium salt solubility might be playing a role?

Hi @LatinXChem I am excited to share my work "Selective Deprotection of Primary Amines Via Transamidation Reaction With Solid Sources of Ammonia" at #LatinXChem23 @GroupGamba #LatinXChemOrg #Org001 @OrgBiomolChem @EurJOC

@jamalrafique Thank you! In fact, in the deprotection reaction to obtain 1, we recover the protecting group 2 for later use in other reactions, this is an advantage because it is not wasted as in other deprotection methods and we do not use transition metal catalysts or purification by CC.

@julia_ur1 @LatinXChem @GroupGamba @OrgBiomolChem @EurJOC Congratulations @julia_ur1 for your interesting work, involving the synthesis of primary aryl amines. Regarding green chemistry, synthesis of 1 and during the reaction the formation of Phthalimide 2, besides 10 equiv. of (NH4)2CO3, will it qualify to be called greener?

Hello everyone, here is my poster for the @LatinXChem virtual conference. This is the project im currently working at the @GroupGamba. Please take a look! I am happy to answer any questions😄. #Org025 #LatinXChem23 #LatinXChemOrg #Sulfur @EurJOC @OrgBiomolChem @CienciasUAndes

@OCortezano @LatinXChem @GroupGamba @OrgBiomolChem @EurJOC Gracias! Sí funcionaría, pero usamos sales de amonio como fuente de NH3 ya que facilita el trabajo con el mismo y evita el trabajo directo con NH3 gaseoso por las dificultades técnicas que supone.

@julia_ur1 @LatinXChem @GroupGamba @OrgBiomolChem @EurJOC Hola Julia, excelente trabajo. Me surge la inquietud de saber si este método podría funcionar si empleas directamente el NH3 para realizar dichas desprotecciones.

@OCortezano Gracias por su pregunta. Nosotros no encontramos un relación entre el rendimiento de la reacción y la naturaleza electrónica del grupo sustituyente. La limitación está asociado a que cuando tenemos esteres, obtenemos también el producto de transesterificación.

@julia_ur1 @LatinXChem @GroupGamba @OrgBiomolChem @EurJOC La otra pregunta es referente a las limitaciones de dicho método. ¿Disminuye o incrementa el rendimiento con grupos activadores?

Me: ok time to run more samples to replicate my data My data:

No piranhas were hurt while making this comic! 🐟 #cartoon #academia #science

Cada día soleado en Bogotá es un milagro 🤩☀️

Safety data sheets are occasionally worth a quick skim if only so you can tell the firefighters what coloured smoke to look out for #HealthAndSaftey #Explosions

@AlexisTigreros No realmente. Son unos sustratos que necesito para ensayar una metodología, aunque sí son nuevos.

@julia_ur1 Les vas a hacer mediciones?

Happy Thursday 💜💜

Bacteria have a small motor that makes them move: By SmartBiology

@ramsastrys @GroupGamba Hello! Thank you for your question. We have a hypothesis as to why it does not work with aliphatic amines. However, we are doing some experiments and checking mechanistic issues to have a final conclusion.

@julia_ur1 @GroupGamba In case of aliphatic substituents on 'N', this reaction appears to be not consistent. Can we attribute any reason?

The last #RSCPosterlive webinar is over, it was wonderful! ⭐🤩 What a touching and useful webinar. Thank you all @MarkLautens @tnoel82 @BessetTatiana @JSanjor 👏 #RSCPoster twitter conference 2023 @RoySocChem

@ACOjedaP @GambaGroup We have not yet done so. But of course, it is one of the next experiments to be carried out. Thank you for your interest in our work!

Looking forward to the latest #RSCPosterlive webinar "Obtaining grants: the struggles academics face in financing their research" Don't miss it. 👀 It's been an exciting 24 hours of great science 🧪 Great job @RoySocChem #RSCPoster

@AlanAguirreSoto @GambaGroup Hi, Thank you for your question. The entries highlighted in green, correspond to the conditions selected as optimal not only in terms of yield but also taking into account temperature, reaction times and ammonia source solid (cost).

@julia_ur1 @GambaGroup In the reaction optimization tables you have some high yield entries that are not highlighted. What is the logic behind the e entries that are marked in green?

@AlanAguirreSoto Thank you!

@julia_ur1 @GambaGroup I like how clean the poster is! Great job in the design.

Excited to see so many scientists from around the world sharing their research on #RSCPoster Twitter Conference 2023. What a great event @RoySocChem 🎉👏🏼 #networks 👩🏼‍🔬🌎