LIMB Lab

Excited to share @LubrisBio’s full length recombinant human #PRG4 (#rhPRG4) / #lubricin drug product is released for an upcoming #dryeye clinical study in Australia. Packing and labelling is complete, and we’re ready for distribution upon ethics committee approval. Stay tuned!

Excited to share a new collaborative study lead by Ali Tamayol’s @limb_lab in Advance Healthcare Materials: microneedles with dissolvable backing for the programmed delivery of #PRG4/#lubricin to treat wounds. #uconn #uconnhealth onlinelibrary.wiley.com/doi/abs/10.100…

Excited to share I’ve been named a Collins Aerospace Professor in Engineering Innovation in the College of Engineering at #UConn! Grateful to the College of Engineering, and School of Dental Medicine. More motivated than ever to continue to innovate on all things #PRG4 #lubricin.

Are you interested in biomaterials and/or biofabrication? Have you ever wanted to attend a conference in France? Well, now is your chance! Consider submitting an abstract to this conference! Abstracts are due Feb. 28th! biomaterials-biofabrication.com

#PRG4 #lubricin AlphaLISA from @RevvityLifeSci! We developed it with @LubrisBio #rhPRG4, showed PRG4 down in Sjogrens tears, now great to have a kit made/optimized by Revvity CustomTeams. LLOQ ~5ng/ml, only 5ul of sample. Great for serum, tears, saliva - and we’ll see what else!

New lab paper, congrats to @ATang029 & thanks to coauthors! #PRG4 deficient mice have altered femur mechanical/structural/material properties, and more calvarial osteoclasts. AND, #rhPRG4 inhibits osteoclast-ogenesis & activity in vitro. In vivo is next?! onlinelibrary.wiley.com/doi/10.1002/jo…

Please join us in congratulating the new Dr. Jacob Quint, who successfully defended his dissertation yesterday! Jacob's work in our lab used tissue engineering techniques to treat volumetric muscle loss, and we're so excited to see what he does next! rb.gy/by79r

Check out our latest review exploring the challenges and opportunities presented by the use of tissue engineering techniques in cellular agriculture: sciencedirect.com/science/articl…

Looking for postdoc opportunities! I'm a Biomedical Science PhD student studying inflammatory bone loss. Please reach out if you're hiring and would like to chat! Interested in bone, cartilage, rheumatology, inflammation, adaptive immunity, and regeneration, but open to all!

Colloidal bioinks with hierarchical pores are developed that are easy-to-print. Printed scaffolds encouraged cell ingrowth, vascularization, and muscle regeneration in animal models. @uconnhealth @limb_lab ow.ly/hh5L30sanon

If you're interested in bioengineered treatments for bone defects, from the cutting edge, through FDA regulation, and into clinical use, check out our latest review paper: onlinelibrary.wiley.com/doi/10.1002/an…

Take a look at our latest publication, a novel treatment for volumetric muscle loss utilizing nanoclay to control delivery of important growth factors: pubs.rsc.org/en/content/art…

Happy Holidays from all of us here at the LIMB Lab! We're looking forward to another year of science and discovery!

Check out our latest publication, an exciting review of skeletal muscle bioprinting in Advanced Materials! onlinelibrary.wiley.com/doi/abs/10.100…