RL Weston Institute

🇵🇸🇮🇱 A child walked 12 kilometres barefoot to find flour for his family. He found no flour and ended up getting lost.

‘I hate it. It sucks. But it didn’t defeat me’: Michael J Fox on pity, Parkinson’s – and a potential cure theguardian.com/film/2024/feb/…

Check out our new paper on pre-print bioRxiv, "Spinal cord pathology in a Dravet Syndrome mouse model"; biorxiv.org/content/10.110… @jantinaod @drelliechilcott @AnnaKeeganUCL @s_schorge @ProfSimonWad @DravetUK @curedravet @GOSHCharity @lifearc1 @UCL_IfWH

‘Hard to know’ if Bruce Willis is aware of dementia condition, wife says theguardian.com/film/2023/sep/…

Why does only 3R Tau form insoluble deposits in Pick's disease? Stellar work from Pijush Chakraborty shows that acetylation promotes aggregation of 3R Tau but blocks aggregation of 4R Tau. nature.com/articles/s4146…

via @NYTimes nytimes.com/2023/09/19/sci…

Evolving prion-like conformers differentially alter postsynaptic proteins in neurons inoculated with distinct isolates of Alzheimer's disease tau. rdcu.be/dmyWf

Why isn’t the university marking boycott getting more news coverage? Up to 1 in 3 final year students are currently learning they won’t graduate with a grade because of the pay dispute. My daughter - along with many others - has been offered £500 as compensation. After spending £27,750 on course fees, and countless hours and stress doing a dissertation that she was proud of, but has now been told may never be marked. This is outrageous. Quite rightly, students are saying they will tear up their unclassified degrees, because this is offensive. These are the kids who didn’t get to do A levels, because of COVID. They are being let down horrendously. I believe we need to do more to stand up and say this situation is unacceptable. Disputes happen. The grown ups should sort it out and do the right thing by these students now #standwithstudents

Next in our @_BSGCT PPE series we have the ⭐️ Prof @gabrilignani providing a talk on "A novel way of designing gene therapy approaches for neurological diseases." bsgct.org/public-and-pat… @ESGCT @ASGCTherapy @GOSHCharity @UCL_IfWH @UCLchildhealth @UCLIoN 🧬

This is a GREAT idea!

Great news for neurodegeneration in general and Parkinson’s in particular. I truly hope these advances will accelerate momentum and lead to similar breakthrough for less common neurodegenerative diseases! Congrats to @MichaelJFoxOrg and all those involved michaeljfox.org/publication/mi…

In two weeks, #eurotau will start (April 27-28, 2023). Which topics will be developed in Lille, France at Eurotau? See the list of speakers and topics: eurotau.fr/?page_id=693

🚨Last chance to apply! Opportunity for a Research Fellow to join Prof Adrian Isaacs' lab (UK DRI at UCL) Exciting project performing CRISPR screening and cell-based assays to investigate membrane repair👉buff.ly/3UakmHK

@ToriesCunts It all plays into their master plan of a US health care system - Cleveland Cinic, Mayo clinic, NYU private enterprises abysmal

More funding desperately needed for all UK brain banks as researchers and funding agencies think they can run on thin air! @QSBrainBank @BankCambridge @BrainBankManc @LNDBrainBank

This is the case for all UK brain banks. Many researchers want to use the amazing resources that brain banks have for vital research. These resources cost money to run yet funding agencies and researchers think they can run on thin air!! #pathologymatters

Promising Alzheimer’s therapy and related drugs shrink brains science.org/content/articl…

NEW Preprint from our group, very happy to share: Genetic variation associated with human longevity and Alzheimer's disease risk act through microglia and oligodendrocyte cross-talk