Calen P. Ryan 🌊

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Calen P. Ryan 🌊

Calen P. Ryan 🌊

@CalenRyan

PhD Research Scientist. Reproduction, Aging, Evolution, & (Epi)genetics🧬Stats and R nerd. Martial Artist. Motorcyclist🏍Outdoorsy⛺️ Aquatec🎧. He/him/eh 🇨🇦

WPG, VAN, CHI, NYC Beigetreten Ocak 2015
1.3K Folgt640 Follower
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Calen P. Ryan 🌊
Calen P. Ryan 🌊@CalenRyan·
Trying to find evolution schemes depicting women. If you have one or wish to contribute, post here! #sciart #evolution (image: Eduardo Saiz)
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Grazyna Jasienska 🇪🇺 🇵🇱🇺🇦
Nothing like children and garden to remind us about passing time. I planted a small stick and now it is a great tree full of fruit. Sorbus aucuparia. Birds will be happy.
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Calen P. Ryan 🌊
Calen P. Ryan 🌊@CalenRyan·
New work looking at how epigenetic clocks and cell composition derived from Illumina EPICv1 and v2 compare, led by our outstanding colleagues @UBC @koborlab Always thrilled to publish with such a great team!
Kobor Lab@koborlab

Ever wondered about compatibility of @illumina #infinium V1 versus V2 #arrays for #epigenetics population studies including #epigenetic age & #risk scores? Check out our newest, courtesy of our wonderful #bioinformatics team and an awesome group of amazing @collaborators - enjoy!

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Calen P. Ryan 🌊
Calen P. Ryan 🌊@CalenRyan·
@natalie_matosin @KieranOD_PhD Thank you! Funny though I've seen responses to our work from non-scientists at both extremes. 1. "Obviously unnecessary study! Of course pregnancy and parenthood ages us!" 2. "Obviously wrong. My aunt had 8 kids and lived to 100". Exactly why we need the science!
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Kieran O'Donnell PhD
Kieran O'Donnell PhD@KieranOD_PhD·
This was not planned but what timing!?! Two studies on pregnancy and biological aging in as many weeks! In this study @CalenRyan and colleagues report that an increasing number of pregnancies associates with biological aging| PNAS pnas.org/doi/abs/10.107…
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Jacob Kresovich
Jacob Kresovich@JKresovich·
@CalenRyan @PNASNews @koborlab @Danbelsky @ChrisKuzawa Congrats Calen!!! We didn’t see too much going on in the Sister Study (mostly older women at enrollment and only cross-sectionals), so I wonder if the aging costs of pregnancy wash out over time. You did a fantastic job with this—beautiful work!
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Calen P. Ryan 🌊
Calen P. Ryan 🌊@CalenRyan·
More broadly, these kinds of studies are highlighting how research in biological aging has often overlooked women and women’s health: we really think more carefully about pregnancy, menstruation, and menopause, when building, testing, and validating measures of biological aging.
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Calen P. Ryan 🌊
Calen P. Ryan 🌊@CalenRyan·
The effects we see are small, and we still don’t know the long-term implications. But this kind of research may one day help us identify who is at the greatest risk and devise ways to support them to minimize any long-term costs of reproduction.
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Calen P. Ryan 🌊
Calen P. Ryan 🌊@CalenRyan·
We measured biological aging using 6 epigenetic clocks, a family of revolutionary tools for studying aging and predicting health and longevity. You can read more about them in my not too out-of-date review article. onlinelibrary.wiley.com/doi/abs/10.100…
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