That’s it. I’m outta here after Elon endorses the White Replacement Theory and Grok undresses women without a response. Twitter was nice while it lasted…
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David J Hunter
333 posts
David J Hunter
@DJHunter_EPI
Richard Doll Professor of Epidemiology and Medicine University of Oxford. Formerly a Dean at Harvard. Chief Science Advisor to Our Future Health.
Beigetreten Kasım 2016
333 Folgt514 Follower
Ghislaine thought she had a get-out-of-jail-free card, after insisting that she never say The Donald do anything "improper ".
Oops.
nytimes.com/2025/10/06/us/…
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@Peter_Fitz only 3 points down at half time at Eden Park - would take that every time!
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Wallabies going alright!
Down 20-17 at half-time, and coming back strong.
How's the AFL Grand Final?
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@venkmurthy @zakkohane Agree - 5 years is enough (one extra year for preclinical instead of undergrad degree).
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To be honest, there is no reason medical schools should require everyone to get an undergraduate degree either.
If you want to, great. But if you don't, it shouldn't be mandatory.
It's adding a ~1 million dollars per doctor between tuition and opportunity costs
Heath Veuleman@HeathVeuleman
If you are not going for a professional license (MD/DO/JD/CPA/etc) then there is absolutely no reason you should get an undergraduate degree (much less a graduate degree). If you want to make real money then you should get a trade license: HVAC, electrician, plumbing, etc. These “trades” are the white-collar jobs of the future. As it turns out: the butcher, the baker, and the candlestick maker will have much more lucrative businesses and much more rewarding lives. Do it now. Enjoy your life.
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@MaxCRoser Tobacco cessation to reduce lung cancer and CVD? Ernst Wynder and Richard Doll.
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At Our World in Data, we spend much of our time counting deaths.
But it’s just as important to know the number of lives saved — even though it is harder to estimate and involves much larger uncertainty.
My Data Insight today includes this chart of some estimates.
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@kamleshkhunti Are these due to sfx? 15-30pct just don’t tolerate. The paradox is that the demand is immense among people who do not have T2D and do not have obesity plus 4 comorbidities and are buying from the internet Wild West. This is doing harm. I cannot understand how this is legal.
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@DJHunter_EPI Co-payment is an issue but we see high discontinuation rates & poor adherence in UK as well despite no co-payments for people with T2 diabetes
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📉 Real-World Semaglutide Use in the U.S.
❌ Many patients deviate from recommended dose-escalation
⚠️ High discontinuation rates seen in practice
🧠 Better support is needed for patients & clinicians
🔗 onlinelibrary.wiley.com/doi/full/10.10…
#Obesity #GLP1 #Semaglutide #RealWorldEvidence
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@mbeisen Small neighbourhood bistro - not fancy
letempsdescerises-restaurant.fr
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@Atul_Gawande @Reuters And nothing says “saving money” like grain rotting in silos, medicines expiring because they can’t be delivered, and scientific studies being stopped before they are completed.
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.@Reuters dive into 100 days of DOGE found staff and funding cuts led to:
-purchasing bottlenecks & higher costs
-paralysis in decision-making
-longer public wait times
-higher-paid civil servants filling in menial jobs
-a science and tech brain drain.
reuters.com/world/us/100-d…
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@Aiims1742 What's behind this steep increase in pancreatic cancer? 🤔
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Incidence of Pancreas and Colorectal Adenocarcinoma in the US
jamanetwork.com/journals/jaman…
Two GI adenocarcinomas (#PancreaticCancer & #ColorectalCancer) with distinct trajectories.
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@nilanjan10c @SashaGusevPosts The data re in the paper Nilanjan but it will be 10 years before the full natural history (modified by treatment) plays out…
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@SashaGusevPosts Important study, but the question of over-diagnosis remains. Ultimately impact on mortality needs to be seen to see if those “missed cancers” were aggressive.
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Huge result! Not only did a polygenic risk score identify a large number of participants with prostate cancer, many of them were low risk by conventional guidelines AND had medium/high-risk disease. That has been a hard needle to thread in other cancers.
Alex Strudwick Young@AlexTISYoung
14% of 55-69 men with polygenic risk scores (PRS) in the top 10% had prostate cancer classified as intermediate or higher risk, a higher percentage than would have been identified using PSA or MRI screening. This seems like a strong argument for integrating polygenic risk scores into prostate cancer screening decisions, especially given the very low cost compared to an MRI.
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Celebrated 35 years in same inner city Leicester general practice yesterday!
Became a teaching, training, research practice
Started in the days when we did our own nights & weekends on-call & had continuity of care
Many up & downs over the years but still enjoying it
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@JeremyFarrar @uk_biobank @wellcometrust @The_MRC And just imagine the contribution @ukfuturehealth will make once the data matures! @JeremyFarrar
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A must read. Again highlighting power prospective large cohort studies, open global science & open access. Thank you @uk_biobank
@wellcometrust @The_MRC Integrating the environmental and genetic architectures of aging and mortality nature.com/articles/s4159…
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@Atul_Gawande @USAID Tragic - and the disinformation adds insult to the massive injury to aid recipients and the US reputation.
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From independent @USAID sources, >800 contracts & awards are being terminated en masse – w the procurement team subject to hourly checks/targets on speed of executing on these terminations. The pace has exceeded the ability to confirm whether lifesaving assistance is affected.
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@paulpharoah I’ll see your MR study and raise you one:
Went, M., Sud, A., Mills, C. et al. Phenome-wide Mendelian randomisation analysis of 378,142 cases reveals risk factors for eight common cancers. Nat Commun 15, 2637 (2024). doi.org/10.1038/s41467…
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1/4 Lots of epi data find an association between alcohol consumption and risk of cancer and now the US Surgeon General is suggesting there should be cancer warnings on alcoholic drinks. But, are the associations causal?
reuters.com/world/us/us-su…
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@mendel_random A big piece of the answer to your question is that the report is said to be from researchers at “Oxford University and CRUK” - CRUK was the funder but obsessively pumps out press releases in the belief that this increases fund raising.
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Why do news outlets keep promoting clickbait dietary epidemiology findings when they’ve been shown to be spurious so often? It was dark chocolate b4 xmas, coffee this morning and milk this evening. ieureka.blogs.bristol.ac.uk
David Spiegelhalter@d_spiegel
Really fed up with ITV News. I did a pre-recorded interview in which I expressed strong scepticism about the 'coffee only good in the morning' story. But they cut all that out, leaving me apparently supporting their credulous story. I really should not be so naive.
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@mendel_random Can’t disagree, especially since the coffee morning/all day finding is not a significant interaction just a stratum-specific association. The dairy CRC/association is probably real however - consistent and backed by the lactase persistence MR.
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David J Hunter retweetet
Elon Musk, the richest man in the world, is threatening to unseat elected officials if they do not follow his orders to shut down the government during the holidays.
Are we still a democracy or have we already moved to oligarchy and authoritarianism?
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