Francis Group 🧪

The Lab // The Laboratory

New preprint: "Ribosomal Synthesis of Ketone-containing Peptide Backbone via O to C Acyl Shift" chemrxiv.org/engage/chemrxi… @cgem_cci @CarlySchissel @NSF @GroupFrancis @UCB_Chemistry @schepartzlab

Happy to share that my final paper from grad school is out in @BiochemistryACS! We investigate how mutations at VLP assembly interfaces affect particle size, stability, and biological function. pubs.acs.org/doi/10.1021/ac…

Check out our review on the current state of biocatalysis. Congrats to the authors. nature.com/articles/s4158…

@avtytla Easy, everyone loves tyrosines

Our colleagues in the degrader field never run out of puns, do they? #ACSFall2023

Come check out our work in the Francis Lab at #ACSFall2023! 🌁🏙🧪🧫

✨ New C-GEM paper in @ACSCentSci! Aminobenzoic Acid Derivatives Obstruct Induced Fit in the Catalytic Center of the Ribosome Congrats to @chon_majumdar, twitterless Josh, @GroupFrancis, @schepartzlab, and @cate_lab on a beautiful collaboration pubs.acs.org/doi/10.1021/ac…

Chem Bio in the Bay Area (CBBA) day this weekend featuring a talk on MS2 fitness landscaping from @PaigePistono and the lab meeting Carolyn Bertozzi 😎

Thrilled to see this paper online! The hystersis enthusiasm was 💯 initiated by Supraja, and we really enjoyed working with my former @GroupFrancis colleague, @obermeyergroup.

Another Graduate Research Seminar in the books - Congrats to Hannah Martin @hannnah_99 on a great talk! Hannah is a 2nd-year in the group studying vaccine design for malignant gliomas.

Hot off the presses, some antibody modification chemistry with our colleagues at Merck and the @Toste_Group! pubs.acs.org/doi/10.1021/ac…

Congrats to @katejdolph on an excellent Graduate Research Seminar! Kate is a 2nd-year PhD student with the group studying the sequence space of IDP-based surfactants for drug delivery.

@avtytla The next bioconjugation method will help you get up that V7, promise

Congrats to Paige and the team---Excited to share our latest application of fitness landscaping!

Tyrosine or bust!!!

@Landry_Lab Congratulations!!

TENURED! Three days since I got the official letter and I'm still in disbelief. I was never the strongest student and never expected to even get into grad school. This win is for all of you who took a chance on me & mí familia ❤️ & all lab members. Thank you, gracias #SiSePuede

Join us Nov 17 | 1:00pm PST for a talk that will light up your Thanksgiving dinner with chemistry. Our "foodolgoist" Prof. Matt Francis @GroupFrancis will discuss some of the chemistry behind your Thanksgiving favorites. Need to register to attend. bit.ly/3CzgEz0

“As soon as I heard her name in Swedish, I sent it, and I got an emoji back immediately — the shocked face emoji 😱. She’s a total rock star, and this is well deserved.”

The group on the whole made quite the showing...Matt wasn't able to stick around for the photo booth :(

Big congrats to Francis lab member Derek Manuel García Almedina, who took home the poster award at last week's QBI conference for his work on tyrosinase-enabled construction of bispecific antibodies!