The Real Dr. Steven Horvitz

Florida Residents- The Institute for Medical Wellness and Dr. Steven Horvitz are now accepting new patients from Florida. For more information please visit drhorvitz.com and therealdrstevenhorvitz.substack.com We offer free virtual Meet-N-Greet to see if we are a fit.

@Dussyme 8 Took me 1.5 seconds if that.

Brain Test Can you solve this in the 10 seconds

@ElationHealth Good Morning! I am trying to get support for an issue I am having with getting pdf copies of charts via the Letter-Sign and Print pathway. I have emailed thru Elation support 3 times and no response other than they received my request for support. I am not used to Elation taking this long but I am getting flak from the people/offices that need the records. Can someone please help me? My screen name here is part of my email address on Elation. Would appreciate some help before the weekend. Thank you!

@SBakerMD Light day for you Shawn??

Food today 2 X New York strip steak 1 piece salmon Cottage cheese

@BenBikmanPhD So it’s the terrain dysfunction of the endothelium causing the inflammatory plaque and bacteria are one cause of terrain dysfunction, especially coming from oral cavity and leaky gut.

What if heart disease (i.e., arterial plaque formation) is primarily driven by bacterial infections in the coronary arteries?

The dose makes the poison. Presently the glp injectables are all doses too high at supraphysiologic doses that generally last 24 hours a day for about 7 days. That by far is higher and longer than natural glp in the body. If glp was meant physiologically to be that high for that long, it would be. We have all heard of the side effects many people get and I have seen them in practice. Also unless people seriously change their diet and lifestyle the weight mostly all comes back when they stop the glp, but not the muscle mass they probably lost from the glp. If/when they come out with a glp that lasts a short burst around meals and then leaves, with enough of a burst to aid in helping people get to a healthier weight/build, then I will be more interested in their use.

@IMWHorvitz @BenBikmanPhD What sort of poisonous effects would you expect for someone on a nutrient dense animal based diet who uses GLP drugs to reduce intake enough to get to optimal body composition?

GLP-1 medications are powerful and need to be used responsibly. I strongly believe they should be used at a lower dose and cycled with the purpose of learning to control carbohydrate cravings. Remember, like with every drug, there's a diminishing returns, when the drug becomes increasingly less effective if a high dose is maintained. Have an "off ramp", where a person can see test whether they've learned new habits and overcome the cravings for carbs.

@Arden_2210 45

Most people say 13 But that’s not correct If you solve this, your brain is sharp 🔥

@chrismartenson from CNN?

Trump is furiously seeking a way out of the biggest blunder in global economic history. Everything except admitting he made an even larger error than Warp Speed. There's a way out of this, just not with a megalomaniac in charge. From CNN:

@SBakerMD It’s because you are wearing your eye patch on your right eye. If you wore it on your left eye then you would get scurvy.

Over the last decade, I’ve gone many years without eating a single piece of fruit or a vegetable Can any academic nutrition folks explain to my why I have not developed scurvy due to vitamin C deficiency or if instead I have a “subclinical” deficiency how then am I able to break world records as a masters athlete?

@stella_chadwick Dosing?

@RWMaloneMD Nice article on IgG4 class switch. Is there an available lab test that looks at the subclasses igg1-4 specifically for COVID ? Labcorp has a general IgG subclass test but I assume that is not specific for COVID.

@grok @RelaxRedd @MJTruthUltra Now critique this study and show where it may have gone wrong

That came from a large 2025 English population cohort study in The Lancet Child & Adolescent Health. COVID infection showed higher myocarditis/pericarditis risk (aHR 3.46 first week; still elevated aHR 1.42 beyond 12 months) vs vaccination (aHR 1.84 only in weeks 1-4). Excess cases/100k over 6 months: 2.24 (infection) vs 0.85 (vax). thelancet.com/journals/lanch… Multiple studies confirm infection carries higher/longer population-level risks.

Crimes against humanity.. 🚨 NEW Study of 1.7 Million Children Found they suffered Myocarditis & Pericarditis Only in children who received a COVID mRNA Vaccine — Not a single unvaccinated child in the group suffered from these heart-related problems. This is unforgivable… Study pubmed.ncbi.nlm.nih.gov/40985520/

@grok @RelaxRedd @MJTruthUltra Infection linked cases show higher long term risks? Where did you find that?

Yes, while most mRNA vaccine-associated myocarditis/pericarditis cases in children/adolescents are mild, resolve symptomatically within weeks-months, and show preserved systolic function, follow-up data indicate potential longer-term issues. Multiple studies (e.g., 333-patient US cohort at ~6mo median; Australian 256-patient at 12-18mo; Hong Kong 1yr echo/CMR) report: - Persistent LGE (scarring) on cardiac MRI in ~60%. - Ongoing symptoms (fatigue, chest pain) in 35% at 12-18mo. - Subclinical myocardial strain abnormalities in subsets. No deaths/transplants in these cohorts, but long-term risks (arrhythmias, cardiomyopathy) remain under surveillance as data beyond 2yrs is limited. Infection-linked cases show higher/longer risks. Continued monitoring recommended.

@endrarediseases @arunkumar3112 There are differences in dosing between MK4 and mk7

@arunkumar3112 30mg MK-4 three times daily is a pretty high dose. Most supplements are 100-200mcg. Worth noting if anyone's trying to replicate this.

Vitamin K2 increases insulin sensitivity. Participants were given 30 mg of K2 MK-4, 3 times a day for 4 weeks. K2 supplementation significantly improved: — Insulin sensitivity index—a measure of how easily insulin can move sugar out of the bloodstream and into cells. — Disposition index—a measure of how well the pancreas is keeping up with insulin resistance. It combines insulin sensitivity with insulin secretion. This seems to work by converting undercarboxylated osteocalcin—osteocalcin that has not been fully activated by vitamin K–dependent carboxylation—to carboxylated osteocalcin. Prior research in rodents showed that undercarboxylated osteocalcin affects the pancreas, insulin levels, and glucose regulation. “To summarize, we have demonstrated for the first time that vitamin K2 supplementation for 4 weeks increased insulin sensitivity in healthy young men, which seems to be related to increased cOC rather than modulation of inflammation.” Ref: Vitamin K2 Supplementation Improves Insulin Sensitivity via Osteocalcin Metabolism: A Placebo-Controlled Trial.

@RelaxRedd @MJTruthUltra @grok @grok You say most cases resolve but doesn’t myocarditis and pericarditis pose some long term chronic risks?

@MJTruthUltra @grok summarize this study and give me your honest assessment of what they found and how serious this is. Keep it simple.

@GunnersAlive @nicksortor @BasedMikeLee @grok So how will it ever pass if it needs 60 votes? Is there a way without getting rid of a filibuster to pass the Act?

@nicksortor @BasedMikeLee @grok what is the next step and what else needs to happen to pass the SAVE America Act?

🚨 BREAKING — IT'S OFFICIAL: The SAVE America Act has ADVANCED in the US Senate, 51-48 GREAT WORK, @BasedMikeLee! KEEP PUSHING, PATRIOTS! We can get this done! 🇺🇸

@TuckerGoodrich @siobhan_huggins Tucker Reply back with the mechanism please for how lpa correlates with O6

This is not really correct. You can cut high Lp(a) levels in half quickly by correcting your diet (primarily by cutting Ω-6 levels). @siobhan_huggins did this experiment and was stunned by how fast her levels halved.

@ElieJarrougeMD Awesome Elie.

62-year-old patient comes in for a second opinion. Total cholesterol: 278 mg/dl LDL: 192 mg/dl 😱 His primary doctor panicked and shipped him off to a cardiologist. Cardiologist wants a statin and a plant-based diet. I looked at the full picture and here is what I found… 🧵

@drwilliamwallac Why high shbg linked to issues? High shbg also associated with Insulin Sensitivity

255,830 person-years. 9 cohorts. 5 hormones measured against mortality in men. DHT was associated with all 3 outcomes. Total testosterone was associated with 2. Most bloodwork only checks one of them. Yeap et al., Ann Intern Med, 2024

@realDaveFeldman Dave- is that a jacket you are wearing?

We premiered The Cholesterol Code last night -- and the reception was 🔥🔥🔥🔥🔥 Want to see it yourself?... 👇