Jane F Ferguson

Elevated plasma 2‐AAA associates with reduced #HDL cholesterol levels. @janefferguson #AHAJournals ahajrnls.org/38WZznD

Happy Friday #Nashville! The uptick we saw in #coronavirus cases last week is continuing, with average %positives now >8%. Overall cases are still low, but let's work together to prevent further increases. Enjoy the beautiful weather this weekend☀️🌸 🌿

Good Morning #Nashville. While #coronavirus remains low, we see a slight uptick in cases, with our moving average %positives now at 5%. Something to keep an eye on 🧐 Stay safe and enjoy the weekend 🌸

@annetkiraboc1 @VI4Research @FrontGenetics Yes! And if we can somehow do research that combines the microbiome and COVID, we will top the citation charts next time for sure 😆

@VI4Research @JaneFFerguson @FrontGenetics Congratulations @JaneFFerguson! We should do more research together. I think we make a super team 😊

Excited to have made the top 10 for highly cited papers, not once, but twice! Thanks @VI4Research

We found that inter-correlations between bacterial taxa increased in obesity, suggesting altered community dynamics. Surprisingly, salivary microbiota provided a more distinct pattern of differentiation between obese & lean individuals than fecal microbiota.

New paper from @Andrei_Bombin's postdoc in the Ferguson Lab 🦠🧬 @JDMosley_Moses @PhysRep @VuBiome Obesity influences composition of salivary and fecal microbiota and impacts the interactions between bacterial taxa physoc.onlinelibrary.wiley.com/doi/10.14814/p…

Recruited a buddy for #WearRedDay It's never too early to start learning about heart health #vumcgored

Really enjoyed delving into this very cool paper from @ironicbonding @EmoryCbl for a News&Views article in @NatMetabolism this month #microbiome #metabolites

How to write a paper

We're Hiring! #postdocjob in #microbiome More info here: medsites.vumc.org/fergusonlab/fe… @VuBiome @VUMCgenetics @VUMC_Medicine

We are interested in the #metabolite 2-AAA, which associates with #T2D and #atherosclerosis. We found that knocking out a key gene in the 2-AAA pathway leads to #mitochondrial dysfunction; perhaps helping to explain the link between 2-AAA and disease.

New Paper Out: Knock-Out of DHTKD1 Alters Mitochondrial Respiration and Function, and May Represent a Novel Pathway in Cardiometabolic Disease Risk frontiersin.org/article/10.338…

Final call: Today is the last day to submit a #MicrobiomeVentureFund application to kickstart new microbiome scholarship. We look forward to your best ideas and new discoveries!

APPLY for @VuBiome Venture Fund to kick-start new microbiome research and education activities @VanderbiltU. Diversity across career stages and schools is encouraged. Deadline for a one page proposal is August 9. What will you discover or learn? news.vanderbilt.edu/2021/07/14/mic…

So, targeting plasma kynurenine directly is unlikely to be effective in disease treatment, but interrogation of SH2B3 pathways during inflammation could identify novel causal cardiometabolic disease mechanisms. @MinooBagheri1 @JDMosley_Moses

Known genetic regulators of kynurenine like IDO, TDO and SLC7A5 did NOT associate with disease, but a missense variant in SH2B3/LNK associates with both kynurenine levels and with disease...

What a nice way to be welcomed back from maternity leave: New paper published today @SciReports rdcu.be/crdLy We examined genetic predictors of the inflammatory metabolite kynurenine, and found associations with cardiometabolic disease, but only with some predictors...

Campus announcement 📢: Vanderbilt faculty, staff, and students can now apply for the @Vubiome Venture Fund to support microbiome scholarship spanning science, art, history, education, policy, law, etc. See thread for more info.