Mohammed D. Al Johani

We did a thing! Super proud to be part of this group.

@wildtypecell Thanks, Aditya! Hit me up early 2024 (🤞) Happy to send you a copy ☺️

@MDJEditing @CSHL Congrats! That looks amazing! When will it be available to buy? :P

Want to make a worm glow? Come say hi! I may or may not have candy (poster no. 57) #cshlCRISPR23 @CSHL

Modular safe-harbor Transgene Insertion (MosTI) for targeted single-copy and extrachromosomal array integration in C. elegans. biorxiv.org/cgi/content/sh… #bioRxiv

Happy to see our paper on piRNA-mediated silencing and transgenerational inheritance in C.elegans in print. Thanks to Sam Gu @ Rutgers for a great collaboration! nature.com/articles/s4159…

1/5 Our paper is out as a bioRxiv preprint. @sonia_elmouridi and @FaisalMAlkhaldi Like MosSCI, just better. Targeted single-copy and array integration synthesizing new and gradual improvements from the past 15 years across many labs. biorxiv.org/content/early/…

I made an opto cell line and it's the coolest thing ever! I feel like a wizard pointing at cells and making them contract 🧙‍♂️. Here is local RhoA activation by recruitment of LARG.

Am I disturbing some sort of ritual?

That dorky sense of accomplishment when you finally find a restriction site for genotyping a knock-in that encodes a flexible linker dipeptide that does not introduce phosphorylatable amino acids. SfoI! In frame, encodes a gly-ala. AND cuts in Phusion HF buffer.

Department: lunch will be provided Me:

Just microscopy 🥰 Love my job

For the friends of 3'UTRs

Looking for a better negative selection marker for C. elegans transgenesis than peel-1? My postdoc and Master's student developed a simple histamine-based system that works like a charm. pubmed.ncbi.nlm.nih.gov/33437931/

Are genomes of identical twins really identical? "Our results indicate that allocations of cells during development shapes genomic differences between monozygotic twins." rdcu.be/cddS6 @NatureGenet

I had to “sink or swim” in my undergrad lab, and because I swam, I assumed it was a good system. After having supportive mentors, I realize I could have learned so much more with proper guidance. Don’t let people sink just because it’s the way it was for you! #AcademicChatter

Me to my ribosomes after I get the vaccine:

Our review (@timlu & Zhong lab) on designing living materials using synthetic biology is out! We covered recent advances & prospects and summarized #synbio tools for programming smart living materials with various functionalities. rdcu.be/ccNg0 nature.com/articles/s4157…

1/n Rounding out the best of 2020 for our lab, newly published “Engineering Cell Fate: Applying synthetic biology to cellular reprogramming.” We review cellular reprogramming+#synbio Vision brought to life in vivid color by @nbwang22 and @beitz_adam sciencedirect.com/science/articl…

Introducing IN SITU GENOME SEQUENCING, a new technology to resolve DNA sequence🧬 and structure🔬 A team effort with @Andrew_C_Payne, @PaulReginato, @eboyden3, @JD_Buenrostro, and Fei Chen science.sciencemag.org/content/early/… This is how it works: (1/8)