Cold Spring Harbor Laboratory

This week at the CSHL Fellows 40th Anniversary Symposium, CSHL President, Bruce Stillman, announced a multimillion dollar endowment to the CSHL Fellows program to attract new scientists and experimental research. The donation will allow the laboratory to fund the fellowship program for the foreseeable future. The fellowship launches the work, such as past fellow Carol Greider, who won the 2009 Nobel Prize in physiology and medicine. Thank you to our generous benefactor and congratulations to our Fellows for continuing to push discovery forward. @JohnAsbury @Newsday newsday.com/news/health/co…

Congrats to Grad Student Alice Wang (@alicew0624) who is conducting her doctoral research at Cold Spring Harbor Laboratory. Wang received a 2026 @PhRMAfoundation Predoctoral Fellowship in Drug Discovery for her research focused on developing a potential treatment for cancer cachexia, a wasting condition where cancer patients lose significant amounts of skeletal muscle and fat. #InspiringDiscovery #ScienceMakesLifeBetter

What did the brain say to the face? Say cheese—Cheese3D that is! See the new discovery platform from CSHL’s Helen Hou, Kyle Daruwalla, and Irene Nozal Martin. @helenxhou, @IreneNozal, @darsnack cshl.edu/say-cheese3d-a…

At CSHL, developmental neurobiologist Gabrielle Pouchelon, an Assistant Professor, and Postdoctoral Fellow Dimitri Dumontier are uncovering how brain development shapes autism spectrum disorder. The Pouchelon lab studies Fragile X syndrome, the most common single-gene cause of autism and they have discovered something entirely new... In early development, the brain builds temporary connections to wire itself. In Fragile X, those connections stick around when they shouldn’t, disrupting behavior and sensory processing. The promise? Reset those connections, and you may be able to restore function. In this clip, Gabrielle Pouchelon discusses her team’s discoveries publicly for the first time—and what they mean for autism. This #AutismAcceptanceMonth, one thing is clear: understanding development is key to changing outcomes. @biorxivpreprint @NFXFoundation #AutismAwarenessMonth #FragileX #InspiringDiscovery #ScienceMakesLifeBetter

CSHL's Professor Michael Wigler is a renowned molecular biologist who, together with his lab, have made pioneering contributions to how we understand the genetic basis of autism today. One major contribution was identifying that some autism cases aren't passed down through families... they happen because of random "copy and paste" errors in DNA that affect brain development. Specifically, Wigler's lab identified copy number variations (CNVs) as a significant cause of sporadic autism. In his own words, hear Professor Wigler discuss his over 20 years of research to paint a complete picture of genetic causes of autism. Watch the entire "The genetic landscape of autism" video: cshl.edu/videos/the-gen… Share with someone you think would be interested in learning more about autism this #AutismAcceptanceMonth. #AutismAwarenessMonth #InspiringDiscovery #ScienceMakesLifeBetter

Cold Spring Harbor Laboratory's School of Biological Science was ranked #1 grad school program for Biological Sciences in New York and ranked #6 in the nation by U.S. News & World Report (@usnews) this week! #GradStudentAppreciationWeek #InspiringInnovation #ScienceMakesLifeBetter

Cold Spring Harbor Laboratory Assistant Professor Semir Beyaz (@beyazlab) contributed to a study finding that a fatty acid in popular fish oil supplements may disrupt the brain’s recovery after traumatic injury, potentially increasing the risk of conditions like CTE later in life. cshl.edu/fish-oil-may-i… #InspiringDiscovery #ScienceMakesLifeBetter #FishOil

On #WorldAutismAwarenessDay, go 1:1 with CSHL's @LucasCheadle as he shares insights from his new @biorxivpreprint preprint on autism's links to the immune system and pregnancy inflammation. #AutismAcceptanceMonth #AutismAwarenessMonth #Autism #ScienceMakesLifeBetter

To close out #WomensHistoryMonth, we recognize women scientists making history every day, including the brilliant scientists at the center of CSHL's Microscopy Core led by Research Assistant Professor & Director, Microscopy, Erika Wee. Get ready to geek out with us on optics, lasers, cameras, and detectors—take a peek inside our high-tech facility in this new video! cshl.edu/videos/a-close… #microscopy #microscopyphotography #InspiringDiscovery #ScienceMakesLifeBetter

Congratulations to CSHL’s @JohnRInglis, Charla Lambert (@lacharlala), and @JasonWilliamsNY for being elected 2025 “#AAASFellow”s by @aaas! Read more about our awardees and their achievements here:  cshl.edu/cshls-inglis-l… #InspiringInnovation #ScienceMakesLifeBetter

CSHL’s @beyazlab built a first-of-its-kind research platform for studying therapy-resistant endometrial cancers. With this new "endometrial cancer in a dish" tool, the team discovered how these tumors evade the immune system and tested several promising treatments, opening the door for future therapeutics. See how researchers will use this tool to advance endometriosis and endometrial cancer discoveries: cshl.edu/cshl-develops-… #endometrialcancer #EndometriosisAwarenessMonth #InspiringDiscovery #ScienceMakesLifeBetter

Sometimes cancer seems to have a mind of its own. In #TripleNegativeBreastCancer, that could be a good thing! Read about the latest breakthrough from @JanowitzTobias, @KleemanSam, @Lab_FURUKAWA, and colleagues at @NorthwellHealth published today in @Nature. cshl.edu/immune-respons… #encephalitis #Inspiring Discovery #ScienceMakesLifeBetter  Image background: Felipe Serrano/Illustra SciLab

This Endometriosis Awareness Month, there’s real reason for hope at Cold Spring Harbor Laboratory. OurDaughtersFoundation gifts $200K to CSHL to advance endometriosis research. cshl.edu/our-daughters-… #EndometriosisAwareness #InspiringDiscovery #ScienceMakesLifeBetter

March is Colorectal Cancer Awareness Month—and the timing couldn’t be more urgent. Colorectal cancer is now the leading cause of cancer death in men under 50 and the second in women under 50. At CSHL, Peter Westcott’s (@PeterMKWestcott) lab is at the forefront of understanding why diagnoses are rising again after declining before the 1990s. His team is investigating how environmental factors may be driving this alarming global trend in younger people. In this clip from his Cocktails & Chromosomes talk, “Cancer: A disease of genes and… garbage?”, Westcott explains why understanding how cancer evolves—and how our environment influences it—is key to prevention. 🎥 Watch the full video at the link here: cshl.edu/videos/cancer-… #ColorectalCancer #EnoughCRC #NationalColorectalCancerAwarenessMonth #ScienceMakesLifeBetter

Congratulations again to the eight winners of our 2026 MIND Prize! 🎉 Learn more about these scientists and their innovative projects here: pershingsquarephilanthropies.org/news/pershing-…

Right on time for this spring weather.... research published today, provides plant breeders a new tool to confront future challenges, from droughts to food scarcity. In a new study in @ScienceMagazine, CSHL's Zachary Lippman lab and colleagues at The Hebrew University of Jerusalem @HebrewU and Sainsbury Laboratory Cambridge @slcuplants more than 2.3 million regulatory DNA sequences conserved across 284 plant species—some more than 400 million years old. Learn more on the "Secrets of evolution found in ancient plant DNA": cshl.edu/secrets-of-evo… #InspiringInnovation #ScienceMakesLifeBetter

For Women’s History Month, Barbara McClintock remembered through a story from her friend and colleague Phil Renna at CSHL—from campus walks in galoshes to cracking black walnuts for her famous pound cake. A rare glimpse at the scientist who changed genetics forever.  @NobelPrize @GeneticsGSA @theNASciences

Congrats to CSHL @corina_amor_MD on winning the 2026 @PershingSqFdn @MindPrize! Her lab is developing a CAR-T strategy for Alzheimer’s disease that targets inflammatory aging cells outside the brain—aiming for safer, long-lasting ways to prevent cognitive decline. cshl.edu/corina-amor-ve… #Alzheimers #Dementia

Every scientific breakthrough has a beginning. As we celebrate Women’s History Month, this episode highlights two women whose determination and discovery are helping define the next generation of scientific leadership. #WomenMakingHistory cshl.edu/podcasts/life-…