Pablo Sáez

16 posts

Pablo Sáez

@PSaez83

Beigetreten Aralık 2021

75 Folgt25 Follower

J. Alegre-Cebollada@AlegreCebollada·17 Kas

🎉🎉 Very happy that our paper “Cell response to extracellular matrix viscous energy dissipation outweighs high-rigidity sensing” is out @scienceadvances science.org/doi/10.1126/sc… A thread on the main findings follows👇 @CNIC_CARDIO @SBEsp @SEBBM_es

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Pablo Sáez@PSaez83·18 Kas

@AlegreCebollada @madelpozo67 @PCusachs @mart1nezdelp0z0 @chuerti @ClementeManteca Congrats to Carla, Jorge and the team! It was a pleasure to get involved in this beautiful work!

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J. Alegre-Cebollada@AlegreCebollada·17 Kas

Our lab was not expert in hydrogels and mechanosensing. Many thanks to our collaborators (G. Plaza, @Psaez83 @madelpozo67 @PCusachs @mart1nezdelp0z0...) for great team work. Special kudos to @chuerti, who led the project, and @ClementeManteca who developed the pull-and-hold model

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Pablo Sáez@PSaez83·13 Şub

@WaleedMirzaPhD @torressancheza @marietabernabeu Congrats!

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Pablo Sáez retweetet

SEMNI @semni_social·19 Eki

Different positions available at UPC-BarcelonaTech, in the group of profs. Marino Arroyo and Pablo Saez, us14.campaign-archive.com/?u=31930e10f93…

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Pablo Sáez@PSaez83·15 Eyl

thrilled to be part of it! @LaCaN_UPC @la_UPC

Pere Roca-Cusachs@PCusachs

The result of hard, detailed, insightful work by @ZanettaKechagia over several years, with great modelling by Pablo Sáez and Marino Arroyo (UPC), and in collaboration with @PWBDerksen, @AEloseguiArtola , and @XavierTrepat labs. Part of @Mechanocontrol project, funded by @EUeic.

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Pablo Sáez retweetet

Pere Roca-Cusachs@PCusachs·14 Eyl

Our new work on nuclear mechanoprotection is now out: nature.com/articles/s4156…

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Pablo Sáez@PSaez83·4 Eyl

We show that how individual tissue components assemble to each other, besides their local densities, is key to accurately modeling brain tissue mechanics

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Pablo Sáez@PSaez83·4 Eyl

Happy to have this work published! Using the mouse hippocampus, we developed a model to predict local tissue mechanics. Thanks to Carlos Borau @M2BE_I3A @Nelda373 @Franze_Lab! 👇 sciencedirect.com/science/articl…

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Pablo Sáez@PSaez83·5 Haz

@RicardAlert @AdamShellard @mayor_lab Thanks! Great work! Congrats!!

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Ricard Alert Zenón@RicardAlert·5 Haz

@PSaez83 @AdamShellard @mayor_lab No, only positive durotaxis and frictiotaxis so far.

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Adam Shellard@AdamShellard·2 Haz

Our pre-print is out! 🧑‍🔬 biorxiv.org/content/10.110… Frictiotaxis underlies adhesion-independent durotaxis A short thread about what we found 🧵 @mayor_lab @RicardAlert

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Pablo Sáez@PSaez83·5 Haz

@RicardAlert @AdamShellard @mayor_lab We found that + & - durotaxis actually emerges from the movement toward + gradients of friction (+ frictiotaxis). Did u find any case of - frictiotaxis?

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Ricard Alert Zenón@RicardAlert·3 Haz

@PSaez83 @AdamShellard @mayor_lab Thanks for the feedback, very helpful! Yes, here our goal was to do it with no adhesion at all, just friction.

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Pablo Sáez@PSaez83·3 Nis

We also propose how cell adhesion can be manipulated to control durotaxis (shift migration directions or arrest migration). And extended the model to describe haptotaxis!

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Pablo Sáez@PSaez83·3 Nis

New paper on durotaxis! We used clutch models and active gel theory to explain positive and negative durotaxis @softmatter See more 👇pubs.rsc.org/en/content/art…

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Pablo Sáez@PSaez83·3 Nis

@LabSwaminathan We have done it using a theoretical model. Fresh from the oven! pubs.rsc.org/en/content/art…

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Swaminathan Lab@LabSwaminathan·3 Nis

Fantastic work on chemoattractant competition. Will be great to see this extended to hapto- vs. duro-taxis cues engaging integrins? Predictions?

Pablo J. Sáez / now posts in a better place (BSky)@pj_saez

Hot from the press @CurrentBiology Competition between chemoattractants causes unexpected complexity and can explain negative chemotaxis, by A Dowdell, et al @robinsall lab. Great story for #CellMigration lovers Full: cell.com/current-biolog… #scicomm

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Pablo Sáez@PSaez83·4 Tem

Our work on wrinkled fingers also featured at @CCMA_cat. @LaCaN_UPC @la_UPC @IMTech_UPC Per què s'arruguen els dits quan els posem en remull i què diu això sobre la nostra salut ccma.cat/324/per-que-sa…

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Pablo Sáez@PSaez83·4 Tem

How & why do our finger tips wrinkle? An old work featured @BBC_Future!! @LaCaN_UPC @IMTech_UPC @la_UPC

BBC Future@BBC_Future

Fingers and toes that wrinkle in water may have evolutionary benefits. bbc.com/future/article…

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Entdecken

@ScienceAdvances @CNIC_CARDIO @SBEsp @SEBBM_es @AlegreCebollada @madelpozo67 @PCusachs @mart1nezdelp0z0