S.ChenLab uOttawa

The 3rd Neural Circuits and Behaviour satellite is happening May 18th at @CAN_ACN in beautiful Montreal. Registration is now open (link below). eventbrite.ca/e/neural-circu…

Orbitofrontal cortex drives predictive filtering of sensory responses | Nature Neuroscience nature.com/articles/s4159…

@JoelWattsLab @xsakuraphie congrats Joel!

Online now in Neuron, the final published version of @xsakuraphie's PhD work on α-synuclein strain generation: Stochastic misfolding drives the emergence of distinct α-synuclein strains: Neuron cell.com/neuron/fulltex…

@tpatriarchi @FellinLab our dream experiments ~~~~~~~

Dual-color two-photon imaging in hippocampus: nLightR2 enables simultaneous tracking of NE release and astrocytic Ca²⁺ dynamics during virtual navigation, revealing tight but heterogeneous neuromodulator-glia coupling in vivo. @FellinLab

The most sensitive green and red #norepinephrine #sensors engineered to date are out in @naturemethods! Deeply grateful to all our funders and contributors who made this work possible. A true team effort. @ERC_Research @snsf_ch @UZH_en @UZH_IPT doi.org/10.1038/s41592…

@tpatriarchi Congrats Tommaso!!!!

Helping researchers turn breakthrough ideas into meaningful health innovations. 🧪💡 The University of Ottawa Faculty of Medicine supports innovative research projects from our investigators as they seek to translate their most exciting ideas into new commercial applications. Designed to bridge the gap between discovery research and real-world application, University of Ottawa Faculty of Medicine’s 3P grant supports early-stage health and biomedical innovations at a critical point—when promising ideas often struggle to advance toward patenting and commercialization. Over the past several years, 3P funding has played a pivotal role in helping Faculty researchers move beyond proof of concept. Discover how the 3P program is helping turn exciting research ideas into real-world health solutions ➡️ uottawa.ca/faculty-medici… @uOttawa

@ArgelAV Congrats Argel!!!

We've been quiet for a while, but we have news! The lab just published in @molpsychiatry a study on sex differences in placebo and antidepressant response to intranasal esketamine for treatment-resistant depression! nature.com/articles/s4138…

Kudos to the world-class researchers at the University of Ottawa Faculty of Medicine on securing new funding from the Canadian Institutes of Health Research (CIHR)! 🎉 Scientists at the Faculty of Medicine are driving discoveries that will enhance patient care, strengthen our health system, and help shape the future of medicine in Canada and beyond. 👏🔬

@hb_cell I guess he's not ready to retire ;-)

CIHR funding rate: 13.6%. Early 2000s: 30%+. Canada’s new $1.7B Impact+ program recruits talent — but without increased Tri-Council base funding, we risk further strain on an already stretched system. We’re calling for $1B over 5 years. Support here: tinyurl.com/33c5av46

2 of the Behavioural Neuroscience review panels (BSA and BSC) were both at 11%. So many of the neuroscientists with grants in these panels (that I have spoken to) are between grants and in real fear of having to close up shop! If we keep funding 4/35 grants, labs will close!

Excited to announce the 3rd iteration of our Neural Circuits and Behaviour Satellite (in conjunction with the @CAN_ACN annual meeting). Registration details soon: can-acn.org/meeting-2026/ See you in Montreal!

Plasmids generated in our recent study are available from Addgene: addgene.org/browse/article… AAV-CAG-FLEX-jGCaMP8m-P2A-CyRFP1 is useful for 2P imaging of Ca2+ and filler signals using a 920 nm laser.

Excited for the publication of our recent work on how pyramidal cells shape the identity of interneurons in the Cortex! Big shout out to @artofbiology and Sherry Jingjing wu! nature.com/articles/s4158…

Using tissue clearing and super-resolution imaging, we found that spine density is highly skewed in apical dendrites of cortical L5 neurons in mice. The middle part had the highest spine density. In contrast, spine density was almost uniform in basal and oblique dendrites. (2/6)

@markbrandonlab Congrats!!! you are on fire ~~~~~~~~~

I’m very happy to share the final version of this, now published in @Nature rdcu.be/eY5nh Hippocampal neurons that initially encode reward shift their tuning over the course of days to precede or predict reward.

UC Irvine Neurology is recruiting a tenure-track or tenured faculty, focusing on molecular, cellular, neurobiological, imaging, genetic, and/or clinical approaches to the study of neurodegenerative disease, with an emphasis on translational application. recruit.ap.uci.edu/JPF09980

Have an idea for an innovative session or event at #SfN26? The submission window for #Neuroscience 2026 sessions is now open! #Neuro Submit your proposal by Wednesday, January 21 - link in replies

Announcing CSHA Course/symposium | June 11–26, 2026 | Suzhou. Learning new imaging techniques in Neuroscience and hands-on projects. Check out cshaneuroimaging.org for course schedule and projects. @CSHANews #Neuroscience #Neuroimaging #Zuolab