Sim Sakong

Exciting research update! 🎉 Together with @Beatfierz and @davidsuter_epfl, we explored how charge in disordered regions flanking DBDs influences target search and pioneering activity. Check it out! 👇 biorxiv.org/content/10.110…

Always nice to share the ideas together! Many THX to who show interest and ideas in our project 🙏 If interested in TF target search, feel free to contact us 📧 @LCBM_EPFL @davidsuter_epfl THX to the EMBL travel grant for me to attend such great conf. 🍀 #EMBLOmics @EMBLEvents

New science awaits! ✨ We are excited to introduce you to our brand-new 2025 EMBL Annual Poster ➡️ embl.org/about/info/cou… In 2025, you can look forward to novel meetings such as the EMBO | EMBO Symposium 'Mechanisms of drug resistance and tolerance in bacteria, fungi, and cancer', as well as tried and true classics like #EMBLCanGen 🙌 #molecularbiology #lifesciencetraining #lifesciences

How did #chemicalbiology approaches empower the study of chromatin #ubiquitylation? Find out more about recent progress that paves new ways to address challenges in chromatin (poly)ubiquitin signaling. 👉#OpenAccess review by @_paulinefranz & @Beatfierz: doi.org/10.1016/j.jmb.…

Check out our work on centro-chromatin, where CENP-A and CENP-B collaborate to generate a dynamic chromatin state! A great collaboration between Nikolina Sekulic’s lab & us @EPFL_CHEM_Tweet, @LabHalic and @tatsuofukagawa1. Congrats Harsh and Ahmad! nature.com/articles/s4146…

Impressions from the LCBM Xmas party.!Happy holidays!!! 🎄🎁🎅🏽

Check out the new review from @CarlosMYruela on the using synthetic chromatin to investigate the function of histone deacylases! doi.org/10.1042/BST202…

Today we’re celebrating with self-made 🇨🇳🇹🇼🇰🇷 hot pot! Thanks to the chefs!

Happy to share this Hypothesis paper from Benjamin Martin, 2nd year PhD student onlinelibrary.wiley.com/doi/10.1002/bi…. 🧵

Mark it in your #BPS2023 planner! Sunday Feb. 19 @beatfierz (EPFL) will be describing his work using #singlemolecule colocalization imaging and #smFRET to directly observe the dynamic architecture of chemically defined chromatin fibers. tinyurl.com/biophys23 for more details.

Come and see the new findings on my work, “Target Search Dynamics Of Sox Transcription Factors” 📰📊if you are in #SanDiego for #BPS2023 @BiophysicalSoc 🗓️ Sunday 1.45 - 3.45 PM 📍 Exhibit Hall BC B184 Protein-Nucleic Acid Interactions I

Our paper made it onto the cover on Genes & Devlopment! Check it out here: genesdev.cshlp.org/content/36/19-…

Interested in cell lineage predictions ? @AlmutEisele will be discussing GEMLI to predict lineages solely from scRNA-seq datasets #EMBOOmics - Tomorrow at 18:10 biorxiv.org/content/10.110…

How do cells regulate changes in protein expression levels upon external stimulation? Happy to share our new preprint addressing this question, by super-talented PhD student Benjamin Martin biorxiv.org/content/10.110… A brief 🧵

I am still wondering whether the creators of ChatGPT are aware that in French, it means : Cat, I farted

Happy holidays from LCBM🎄🎁 The weather is snowy, the vin chaud is good and all are well. Take care and see you next year, oh wait no, group meeting on Monday

Excellent talk by @Beatfierz using semisynthesis to dissect dynamic protein regulation by post-translational modifications #ISCB2022 @NCCR_ChemBio

@klausenhauser @LCBM_EPFL @NCCR_ChemBio @Po_Han_Chang @_paulinefranz @CarlosMYruela @k_makasheva @AlexaTeslenko @WeiCaiWell @yujikamei @berlina_yana Yes it is 😉

@LCBM_EPFL @NCCR_ChemBio @Po_Han_Chang @_paulinefranz @CarlosMYruela @k_makasheva @AlexaTeslenko @WeiCaiWell @SimSakong @yujikamei @berlina_yana Ohhhhhh yum! The one in Paquis?

Great Korean dinner concluding an exciting first day at @NCCR_ChemBio #ISCB2022 in Geneva. Come check out our posters tomorrow!

How to crack the tubulin code? Check out the new story from us @EPFL_CHEM_Tweet & @AumeierLab @UNIGEnews on the development of semisynthetic tubulin, now out on bioRxiv! A great collaboration with the lab of Pierre Gönczy @epflSV & many more... biorxiv.org/content/10.110…