Griffin Lab

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Griffin Lab

Griffin Lab

@The_GriffinLab

Structural biology lab @Bio21Institute @UniMelb led by Mike Griffin.

Victoria, Australia Beigetreten Şubat 2019
79 Folgt249 Follower
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Leann Tilley
Leann Tilley@LeannTilley·
Excited to see our study published in @PLOSPathogens. Multi-stage activity & single oral dose killing of P. falciparum in vivo. Structural basis for improved potency and selectivity of this reaction-hijacking inhibitor are revealed. doi.org/10.1371/journa…
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Melbourne Protein Group
Melbourne Protein Group@MelbProtein·
SAVE THE DATE! Excited to announce the 22nd Melbourne Protein Group Symposium will be hosted at WEHI on Thursday 11th July 2024. Spread the word to other graduate research/ student colleagues. Details of keynote speakers and abstract submission to come.
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Melbourne Protein Group
Melbourne Protein Group@MelbProtein·
Don't miss out on your opportunity to attend and participate in Biomolecular Horizons 2024, held in Melbourne!  
YOUNG SCIENTIST PROGRAM- LAST CHANCE- application deadline extended to Friday 8 March @bmh2024Melb bmh2024.com/young-scientis…
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Griffin Lab
Griffin Lab@The_GriffinLab·
Great fun to work with @NatalieASims reflecting on new insights from the Garbers lab doi.org/10.1111/febs.1…, and open questions still to be answered surrounding craniosynostosis-associated variants in the IL-11 signalling machinery! febs.onlinelibrary.wiley.com/doi/10.1111/fe…
Prof Natalie A Sims@NatalieASims

Interleukin 11 (IL-11) receptor complex mutations are associated with craniosynostosis, but how does it happen? @The_GriffinLab and I had fun writing this editorial for @FEBSJournal based on new work from the Garbers lab - so much more to learn! febs.onlinelibrary.wiley.com/doi/10.1111/fe…

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Griffin Lab
Griffin Lab@The_GriffinLab·
Great to see this beautiful work published today. And wonderful to be part of the global team advancing this amazing program! nature.com/articles/s4146…
Leann Tilley@LeannTilley

#Malaria parasites are specifically targeted by a new class of reaction-hijacking inhibitors. Targeting a tRNA charging enzyme, #OpenSourceMalaria compound causes parasites to self-destruct. An amazing collaborative effort from multiple sites across the globe. #Drugs #Parasites.

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Griffin Lab
Griffin Lab@The_GriffinLab·
Congratulations Riley! Was quite a journey to get this out there - a huge credit to Riley for his hard work and determination.
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Rachel North
Rachel North@rachel_a_north·
Excited to share our reviewed preprint on a TRAP transporter doi.org/10.7554/eLife.… in @eLife where an unexpected dimeric assembly was used to obtain a high-resolution structure. Big thanks to Michael Currie, @_jamesdavies and @dobson_lab, along with our fantastic collaborators!
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Leann Tilley
Leann Tilley@LeannTilley·
I am pleased that our review entitled: Targeting Aminoacyl tRNA Synthetases for Antimalarial Drug Development, in Annual Review of Microbiology is now available Open Access. doi/10.1146/annurev-micro-032421-121210. @WinzelerLabUCSD @The_GriffinLab @IRBBarcelona @MalariaPapers
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Leann Tilley
Leann Tilley@LeannTilley·
Excited to see our #malaria pre-print dx.doi.org/10.21203/rs.3.…. An amazing collaborative effort from many sites across the globe to define the mechanism of action of a promising new class of reaction-hijacking inhibitors, targeting a tRNA charging enzyme in malaria parasites.
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Melbourne Protein Group
Melbourne Protein Group@MelbProtein·
PLACEHOLDER! MPG Symposium is being held late this year due to the exciting addition of combining with @RACI_VIC #CHEM2023. Whole meeting will run Tue 23rd Oct - Thurs 25th Oct. Keep your eyes peeled for more info... #protein
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Leann Tilley
Leann Tilley@LeannTilley·
A thoughtful commentary on our nucleoside sulfamate antimalarial work and an insightful reflection on the history of nucleoside-based anti-infectives. I loved reading about the contributions of Gertrude Elion. cell.com/cell-host-micr…. @odomjohnlab @SeshMDPhD #malaria
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Entdecken

@PLOSPathogens @NatalieASims @bmh2024Melb @KazemAsadollahi @Danscooter @gnljameson @riley_dm @big_french_man