Vasilis Samelis

We just made history. In our thousands and in our MILLIONS 🇵🇸 #CeasefireNOW

Explore the world of Shigella infections with our latest review! From historical challenges to recent breakthroughs, we delve into the story of animal models in Shigellosis research 🐭🐰🐵🐹🐟 Thank you @COdendall for writing it with me! sciencedirect.com/science/articl…

We each do our best to reduce our environmental impact at home and in the workplace, but meanwhile the government approves a new oilfield. How can this possibly be justified to meet climate targets?! Appalling leadership. action.greenpeace.org.uk/stop-new-fields #StopRosebank

❗️BREAKING❗️ ‼️new class of interferons‼️ 🏃🏽‍♂️The Sprinter-ferons🏃🏽‍♀️ 5 family members identified! Fighting cancer but also very much engaged in host-pathogen interactions! @BenWiggins_093 @CIliakis @kfibu @VSamelis Get the scoop?! @CellCellPress @ScienceMagazine @Nature

fundraise.cancerresearchuk.org/team/the-sprin… This month, the Sprinter-ferons (@BenWiggins_093 , @CIliakis , @kfibu , @sandpiper_89 and I) are running 60 miles (~96km) to help raise money for Cancer Research UK! Visit the link to donate!

Influenza-induced lasting changes to lung immunity: Emergence of reactive bone marrow monocyte-derived AMs or training of embryonically-derived AMs? Check out our discussion with the Yao lab on the identification and distinction of these phenomena here! nature.com/articles/s4159…

I'm very happy to share our work, which shows the importance of aryl hydrocarbon receptor signalling in lung endothelial cells to promote tissue tolerance and protection against respiratory virus infection. nature.com/articles/s4158…

I am delighted to announce our manuscript on aryl hydrocarbon receptor (AHR) ligand sensing by gut endothelial cells is now out in @Nature! This has been a lot of collective hard work over the last 3 years, and I am proud to see this work across the line! nature.com/articles/s4158…

Delighted to share our latest work on the molecular signals that drive steady-state and emergency bone marrow exit of #DendriticCell progenitors, led by @MarianaPdCosta, out now in @CellReports ! A 🧵... (1/x) cell.com/cell-reports/f…

💥The Minutti lab is recruiting a #postdoc and a research assistant @Neuro_CF to study dendritic cell #DC function and development in infection🦠🪱 and cancer If you are interested in #Immunology, apply here: euraxess.ec.europa.eu/jobs/136711 euraxess.ec.europa.eu/jobs/136735

How is the network of #DendriticCells in tissues maintained and expanded during inflammation? Very happy and proud to share our work identifying the molecular cues driving pre-cDC bone marrow exit during virus infection 🦠🫁 @CellReports @ReiseSousaLab cell.com/cell-reports/f…

And it is out! Fantastic work from @lopix81. MAITs, type I IFN and bacterial infection… check it out! bit.ly/3Ox5oub @JExpMed Thanks to our collaborators and funders @josebengoechea @BBSRC @TheCrick @KCLImmunoMicro @KCL_CIBCI

Latest from the Lab @TheCrick. The transition from IgM to affinity-matured IgG #antibodies is vital for effective humoral immunity. @LZhang1807 identified a unique transcriptional mechanism required for IgG1+ B cell positive selection in #germinalcenters tinyurl.com/3rdunjka

How are antigens retained in germinal centres after immunisation? Our paper is out in @NatImmunol. We show that antigens centralise on the FDC network concomitantly with the formation of the GC. rdcu.be/dgL3K

Andreas Wack and his team have figured out how the ability for cells lining the lungs to become specialised, and thus their ability to help repair the lungs after injury or infection, is dependent on the specific nutrients they use ow.ly/nFAe50MQUE4

Excited to share our review for the @theNCI Ras Initiative on the rationale, progress and challenges of combining KRAS inhibitors with immunotherapy in lung cancer! cancer.gov/research/key-i…

Paper accepted! A new function for CD1d controlling lipid metabolism in macrophages. Check it out! Excellent work from Phil and @lauren_v_evans and thanks to collaborators @cardiffuni @KCL_CIBCI @KCLImmunoMicro @TheCrick @NatureComms @BBSRC nature.com/articles/s4146…

Excited to share our latest work with @sdecarne where we developed a novel preclinical immunogenic model of KRAS-mutant lung cancer which can be used for the evaluation of targeted and immunotherapy combinations. Out now in @CR_AACR ✨ aacrjournals.org/cancerres/arti…

Our work with @philipeast and @JulianDownward on #KRAS oncogenic signalling and resistance to therapy in lung adenocarcinoma (#LUAD) is out in @NatureComms! Tweetorial 🧵 Please share 🙂 nature.com/articles/s4146…

Our study showing that severe COVID-19 in the aged organism is caused by an age-dependently impaired type I and type II interferon response, is now available in @JExpMed! Congrats and thanks to all collaborators, especially to first author Julius Beer! @MartinSchwemmle