Journal of Experimental Medicine

BACH2 controls #ILC3 function via PPARγ-dependent mitochondrial #metabolism. From Jianye Wang, Ying Wang, Gaoyu Liu, Jie Zhou, Qiang Liu, Zuoqing Song, and colleagues: hubs.la/Q04gBKTB0 📘 From #Inflammation Resolution 2026: hubs.la/Q04gBQXp0 #KSInflammation26

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@KeystoneSymp @Zhijuan_JExpMed See our new collection of recent publications on inflammation and its resolution: rupress.org/jem/collection…

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Attending @KeystoneSymp joint meetings #KSTumorMicro26 #KSInflammation26 and interested in discussing publication with our editor? Make sure to get in touch with JEM's Zhijuan Qiu @Zhijuan_JExpMed, who will be there! 📩 Email Zhijuan: hubs.la/Q04gDcR20

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Mesenteric #macrophage-#monocyte circuit controls systemic #inflammation during enteric bacterial infection. From Jiseon Kim, Jinki Yeom, Ki-Wook Kim @KiwookKimLab et al.: hubs.la/Q04gClqD0 📘 From #Inflammation Resolution 2026: hubs.la/Q04gCz180 #KSInflammation26

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Journal of Experimental Medicine@JExpMed

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Journal of Experimental Medicine retweetledi

Rafa Blanco Domínguez@RafaelBlancoDom·2d

We recently identified that Treg cells are expert saboteurs of anti-tumor γδ T cells. 🔎 Read more at J Exp Med! Thanks to @BSilva_Santos @AndreMVPs Sofia and team involved

.@RafaelBlancoDom, @BSilva_Santos, Sofia Mensurado et al. @GIMM_Institute demonstrate that regulatory T cells constrain IFNγ-producing γδ T cells by competing for IL-2, thereby limiting their expansion and anti-tumor function. hubs.la/Q04gsqBz0 #TumorImmunology

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Read Sensing of metabolic signals via GPR183 promotes occupation of lung #macrophage niches by #monocytes rupress.org/jem/article/22…

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“The handling of the transfer by the JEM editors and staff was excellent.” — Tim Willinger, Principal Researcher, Karolinska Institutet, Stockholm, Sweden hubs.la/Q04dcXC70

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Huang, Miller, Felices et al. (@umnmedschool) developed a highly efficient nonviral knock-in platform for #NKcells, enabling plasmid-based genome editing with up to ∼90% knock-in efficiency and ∼100% recovery. hubs.la/Q04gpsL50 #Leukemia #Lymphoma #LymphocyteBiology

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Română

📽️ New video summary from a study, Alternatively activated monocyte-derived myeloid cells promote extracellular pathogen persistence in pulmonary fungal granulomas, from @yufanzheng7 et al. of the @EricVDang1 lab (hubs.la/Q04gcMyS0) 👉 hubs.la/Q04gcKvF0

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📽️ Here's a video summary of the study from @yufanzheng7: youtu.be/zuFiOzNMSg4

YouTube

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Journal of Experimental Medicine@JExpMed·21 Nis

New study from the Dang lab @ragoninstitute reveals a spatial TH2-STAT6 immune checkpoint in pulmonary #granulomas that suppresses extracellular clearance of #Cryptococcus, promoting persistent infection. @yufanzheng7 @EricVDang1 hubs.la/Q04cTwKn0

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Jie Li, Yousuke Takahama et al. @theNCI show that thymic epithelial CCL25 facilitates T cell positive selection in the thymic cortex, whereas intestinal epithelial CCL25 promotes nutrient sensing in the small intestine. hubs.la/Q04gh26f0 #MucosalImmunology #TCells #Thymus

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Megumi Tatematsu, Takashi Ebihara (Akita University) et al. show that CNOT3 promotes the degradation of Tbx21 and Rorc mRNAs through Roquin and ZFP36L1 in #ILC2 cells, thereby inhibiting type 1 and type 3 plasticity and maintaining ILC2 function. hubs.la/Q04ggSjw0

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