Craig Wilen

HIV joining the circular RNAs Club ? Welcome ! nature.com/articles/s4156…

Congratulations to @SteitzLab ! 🎉🎉🎉

Excited to share an amazing video on the NLRP3 inflammasome pathway generated by talented Ann from the Iwasa lab @janetiwasa @Ann_HuiLiu. It shows the real cryo-EM structures of the pathway from #NLRP3, #ASC, #caspase-1, #GSDMD, #IL-1b, to #NINJ1. #cryoem @LeXiao17 Enjoy

Excited to share our new paper in @CellCellPress with @MarcoRuella, led by @Shan_Liu_ and @PuneethGuru_. CAR T cell therapy loses effectiveness over time due to metabolic exhaustion, but we found a surprisingly simple approach to address it. 👇 cell.com/cell/abstract/…

Congratulations to Dr. Pena-Hernandez @marioph13 on his outstanding thesis defense today! We couldn’t be more proud! Both the Wilen and Iwasaki labs will miss you. @VirusesImmunity @Yale_LabMed @YaleIBIO

Increasing evidence that STING has functions beyond DNA viruses. A new study reports that STING restricts influenza infection, independently of IFN. This work complements prior studies that STING prevents infection with diverse RNA viruses. science.org/doi/10.1126/sc…

New study from Wade Schulz, MD, PhD (left) & @ThomasDurantMD of @YaleMed in @clin_Chem_ADLM evaluates performance of quantum machine learning algorithm—quantum circuits w/data re-uploading (QC-REUP)—compared to classical machine learning & other QML methods rb.gy/y9mmj6

New in @JVirology: How does the human norovirus particle assemble? Particle assembly is facilitated by VP2 acting as a molecular bridge. We also share intriguing features making pandemic HuNoV VP2 unique in structure and sequence. journals.asm.org/doi/10.1128/jv…

Grea paper. Congrats to the Lee lab @Yale_LabMed

A nice write-up from Nature Immunology about our recent paper! nature.com/articles/s4159…

I'm trying to train Claude to read the weekly emails from my kids school and reliably summarize them and print a list of action items. It is losing its damn mind and rapidly spiraling into madness. I feel vindicated

On the balance of knowledge dlvr.it/TQnN9N

⚠️ If you’re reading this, you’ve been infected* ⚠️ *~95% the human population has been infected by the Epstein-Barr Virus (EBV). Today in @Nature with @nyeo_sherry, @EMC22381830, @RyanDhindsa @SlavePetrovski, we shed some light on what happens next. nature.com/articles/s4158…

Happy to share our new paper @PLOSBiology on crosstalk between interferons and tissue repair. IFNs are critical for antiviral defense but excessive production is linked to delayed recovery. We found that at high concentrations, IFNs co-opt the downstream portion of the Hippo developmental signaling pathway to curtail epithelial repair and regeneration. Huge congrats to first author @krupa_subs and co-authors @YaleMed @Yale_LabMed @YaleIBIO journals.plos.org/plosbiology/ar…

Congratulations to @mnleeee, assistant professor of Laboratory Medicine @YaleMed, for being among 19 renowned researchers chosen for a prestigious research award from a partnership of @AmericanCancer & Yosemite, a venture capital firm dedicated to making cancer non-lethal. shorturl.at/K4IvB

Nice summary of our recent work on variation in common cold infections @WSJ wsj.com/health/cold-vi…

Rhinoviruses cause common colds & asthma attacks but are also often benign. Our latest paper delves into why--check it out at cell.com/cell-press-blu… Kudos to first author Bao Wang and team members @JulienAmat1, Valia Mihaylova, Yong Kong, & Guilin Wang @YaleMed @Yale_LabMed @YaleIBIO

Only 3 days left to apply for a Summer Internship in the Yewdell Lab. Don't miss out on the chance to gain exposure to what a job in "industry" actually looks like, and get a leg up towards advancing your career. Apply now! roche.wd3.myworkdayjobs.com/ROG-A2O-GENE/j…

Writing is thinking. Don't let AI do it all.

Congratulations to Dr. Ryan Flynn, who has been promoted to Associate Professor at Harvard (HSCRB)! We are delighted to celebrate your achievements and look forward to your continued success.