Mark Lee

It just seems implausible this is what we are made of, essentially, nanotechnology about a billion years beyond anything we can design or make ourselves.

That DeepMind documentary (“The Thinking Game”) now has ~300m views on YouTube. The most replayed scene is a meeting when someone tells Demis that AlphaFold can “easily” predict all known (1-2B) protein sequences “in a month”. He looks up from his phone and says “Why don’t we just do that? That’s a great idea. We should just run every protein in existence and then release that.”  That would ultimately lead to the Nobel Prize. Interesting backstory from WSJ on how they were able to capture the footage of the meeting: a former NFL Films director (Greg Kohs) had done some commercials for Google and they asked him to do the documentary for the famous 2016 AlphaGo match with Lee Sedol. After that project, Kohs realized he should just do a documentary on DeepMind (Google would own rights but he had full editorial final cut). He spent a ton of time with Demis and Co from 2018-2024, and that’s how he got that incredible moment of Demis and AlphaFold (including the moment they released it to the world). *** More from Ben Cohen at WSJ: wsj.com/tech/ai/google…

Congratulations to @mnleeee, assistant professor of Laboratory Medicine @YaleMed, for being among 19 renowned researchers chosen for a prestigious research award from a partnership of @AmericanCancer & Yosemite, a venture capital firm dedicated to making cancer non-lethal. shorturl.at/K4IvB

Congratulations to all the @aabb Foundation Honorees & Grant Recipients including @Yale_LabMed’s own Drs. Mark Lee and Sean Gu #aabb2025

@thechoilab @CellReports @srviswanathan Congrats Peter and team!

First paper from the lab out in @CellReports! (cell.com/cell-reports/f…) A great collaboration with @srviswanathan and many others, check out his tweetorial 👇 for more info

@srviswanathan @thechoilab @CellReports @CaP_pubs @stephentang23 @vidya_sethu @jiaoli43141960 @sarahaboualaiwi @xyzxiaoyang @JohnDoench @TakedaDavid That’s great! Congrats!

Happy that, on this numerically special Tuesday (2/22/22!), our work with @thechoilab on PRMT1 as a vulnerability in prostate cancer is published in @CellReports: cell.com/cell-reports/f… #prostatecancer #pcsm @CaP_Pubs A 🧵 (-2/7)

Congrats to Matthew L. Meyerson, MD, PhD, of @DanaFarber, our #GiantsCC21 in Prevention/Genetics!

@thechoilab @NIH_CommonFund @LilingWanLab @MustafaMir16 @KorbLab Well deserved Peter, congratulations! Excellent opportunity for postdocs to work with a great mentor!

Happy to receive the New Innovator Award from @NIH_CommonFund to explore crosstalk between epigenetics & RNA splicing! #NIHHighRisk We are hiring postdocs so reach out if you're interested! Congrats to all awardees, esp. fellow CHOP/Penn @LilingWanLab @MustafaMir16 & @KorbLab

A new method developed by @DanaFarber, @broadinstitute scientists @meyersonlab, @mnleeee identifies specific #antigen parts, or epitopes, among peptide pools – akin to finding needles in a haystack: fcld.ly/8u7ck51 #immunology

@xyzxiaoyang @meyersonlab Thanks Xiaoyang!

Congrats @mnleeee and @meyersonlab Great work!

@xyzxiaoyang @meyersonlab @MatLupien @Sven_Bailey @thechoilab Congrats Xiaoyang!

Excited to share our latest work showing how the KLF5 oncogenic transcription factor acts in the 3D genome of epithelial cancers. This work continues a tradition of @meyersonlab and @MatLupien alumni/friends @Sven_Bailey @thechoilab working together. cancerres.aacrjournals.org/content/early/…

We talked to Curtis Rogers, co-founder of GEDMatch. Before he hung up on us, he said you're not supposed to upload DNA without a person's permission. technologyreview.com/s/611038/inves…

Brilliance from @mcsweeneys as always: Oh, the Shit You’ll Do After You’re Tenured! - McSweeney’s Internet Tendency mcsweeneys.net/articles/oh-th…

A whole new look at past State of the Union addresses, now annotated on @Genius → go.wh.gov/GeniusSOTU #SOTU

@harvardmed MD/PhD graduating class of 2015. Amazing physician scientists. Really quite inspiring stories.

GM rice delivers antibodies against deadly rotavirus nature.com/news/gm-rice-d… @naturenews And the original paper in JCI jci.org/articles/view/…

Crowdsourcing Economics: 3 UC Berkeley profs are crowdfunding for development economics research in Uganda. bit.ly/122YeiZ

HealthPartners: bringing housecalls back... RT @adamwolfberg: How a huge private practice is cutting health care costs: theatlantic.com/health/archive…