

APODDC
111 posts

@apoddc
We’ll be hosting Clinical Trial Design webinars in 2023! Follow us to be kept up to date. 📊🧑🏻💻












🏅 Cheers to the Top 5 JTO CRR Reviewers of 2024! 🏅 Your dedication advances lung cancer research—thank you! 👏 Paolo Bironzo, Nicolas Girard, William Evans, Hidehito Horinouchi, Pei Jye Voon 🔹 Apply for the 2025 Reviewer Workshop by April 1: bit.ly/ReviewerWS #WCLC25

Selpercatinib in RET Fusion–Positive Non–Small Cell Lung Cancer #NSCLC 🫁 : Final Safety and Efficacy, Including Overall Survival, From the LIBRETTO-001 Phase I/II Trial buff.ly/YlqitQJ This phase I/II study evaluating selpercatinib in RET fusion-positive non–small cell #Lungancer (NSCLC) saw Final results with durable efficacy, an objective response rate (ORR) of 62% in patients who had prior platinum-based chemotherapy and 83% in treatment-naïve patients. The duration of response (DoR) was 31.6 months and 20.3 months, respectively, and progression-free survival (PFS) was 26.2 months for pretreated and 22.0 months for treatment-naïve patients. At 3 years, 57% of pretreated and 66% of treatment-naïve patients were alive. Selpercatinib also demonstrated an 85% ORR in patients with CNS metastases. @GautschiOliver @bensolomon1 @herbloong @geoff_oxnard @alexdrilon

Biomarker-selected or biomarker-agnostic ADCs for oncogene-addicted #NSCLC❓ 💡Just out in @myESMO #CancerTreatmentReviews a comprehensive overview on current landscape, challenges and perspectives Grateful to work with a global amazing team, including @stephanieplsaw @HendriksLizza @JessicaMenis Tina Cascone @ogarrieta @DrJNaidoo @Alfdoc2 @peters_solange and senior author @JordiRemon Link to the Review:👇 doi.org/10.1016/j.ctrv…



What a privilege to have an academic of the quality of @herbloong speaking at @NzsOncology on precision oncology. Kia Ora Herbert!

























