Dee Scientist

China is writing the playbook for integrating AI into manufacturing, setting the blueprint for how the next era of industry will operate.

About 7,000 steps/day is associated with ~50–70% lower mortality vs low activity jamanetwork.com/journals/jaman…

2026 might be the year we start aging backwards we're barely into Q2 and here's what's already happened: 1. Life Biosciences got FDA clearance for the first human trial to reverse cellular aging. Not slow it. Reverse it. Results expected by year end. 2. Kyverna filed for the first CAR-T approval for autoimmune disease. One injection. Every patient eliminated their immunosuppressant drugs. A single dose. 3. Retro Biosciences dosed the first humans with RTR242. A pill that reactivates the brain's cellular cleanup machinery to fight Alzheimer's. Phase 1 results expected Q3. 4. Baby KJ became the first human to receive a personalized in-body CRISPR edit. Custom therapy designed in 6 months. It worked. His doctors are now building the FDA pathway for bespoke gene therapies. 5. ClockBase Agent analyzed 2M+ molecular samples, tested 43,529 interventions, flagged 5,756 compounds that modify biological age, then validated the top candidate in old mice. The system gets sharper with every cycle. 6. The FDA just officially moved to reclassify a dozen restricted peptides. The ban is coming off. Stanford separately discovered a natural Ozempic with no side effects using AI. Peptides just became a regulated market. the pattern is clear - discovery timelines collapsed. years to weeks. - validation moved upstream. mice to humans. - the target expanded. single diseases to aging itself. first FDA-approved drug that demonstrably reverses biological age by end of 2026? bio/acc

Read about it here : open.substack.com/pub/agentic1ed…

China is writing the playbook for integrating AI into manufacturing, setting the blueprint for how the next era of industry will operate.

Gut bacteria was transferred from depressed humans to rats. The rats developed features of depression.

You need a quest. It's tempting to pursue ease, but one thing I've come to learn: The easy life can quickly start to feel like the meaningless life. The least happy people I know are those who lack challenging quests in their lives. There's nothing better than hard-earned progress. The struggle. The pain. The grit. The resilience. And then, the breakthrough. The knowledge that you paid the cost of entry to achieve the growth you went after. Hard, meaningful quests are good for the soul. Learn a new skill. Start a side business. Travel to a new place with no plans. Take on a difficult physical endeavor. Just do something hard. You need a quest.

this is nuts! Mark Cuban just said something every young person should hear. AI agents are GOING to run through every small and mid-size business in the country. not a single one of those owners will know how to build them. his advice is to learn claude. learn agentic workflows. just learn AI and how it works. then go to these businesses and help them because they won’t know how to do any of this shit. they have money to spend. they have deep problems. they don’t have you!

@brettcalhounn Starting a company is scary, but once momentum builds, and you have a repeatable business case - you are in a great position. On the other hand, in the life of conformity, if a curve ball like a lay off is thrown at you, you are out on your own to figure things out. Hopefully.

People say starting a company is scary, like living a life of conformity isn’t.

How long will you live? That's the wrong question. How long will your brain work well enough for your life to have autonomy? That's the one longevity medicine has been ignoring. Lakhan (Cureus, 2026) calls it brainspan: the window during which your neural networks support independence, adaptive capacity, stable sleep, and coherent body regulation. Five systems define it: cognitive networks, autonomic regulation, sleep architecture, emotional circuits, and behavioral adaptability. When these degrade, lifespan may continue. But the person inside it doesn't. Your brainspan constrains your healthspan. Not the other way around. Every longevity protocol should start with the organ that determines whether the rest of your body's extra years are worth living.

@slavov_n Nothing is set in stone in science. New insights change perspectives.

A periodic reminder to leave behind simplistic & naive notions.

Agentic AI isn’t just a fancy analytics tool. It can make decisions and execute actions in real-time. Processing unstructured data, predicting trends, optimizing resources, and speeding up drug development, autonomously.

The future of pharma is real-time, intelligent, and autonomous.

Why Pharma is perfect for Agentic AI: - Large, highly specialized teams - Immense data volumes - But knowledge often trapped in silos - Coordination across discovery, translational research, clinical, & regulatory is slow & fragmented. #Agents #AI

The signals are clear: agentic AI has immense potential to transform workflows in pharmaceutical organizations. Some of the fastest paths to ROI are right here.

Pharma runs on massive, siloed data. Agentic AI breaks barriers streamlining processes, unifying data, and speeding results. I explore this topic in greater depth in my new substack article.

The Rise of Agentic AI in Pharma: From Tools to Execution Engines open.substack.com/pub/agentic1ed…

If you really want to hold yourself to a high standard, graph the growth rate of the number you care about instead of the number itself. Then you're winning if you can even keep it flat.

If you're in tech / research/ science let's #connect !

In my new substack post, i talk about how @ycombinator 's resources helped me get started.