Cecilia Padilla-Iglesias

🚨FULLY FUNDED PHD POSITION!🚨 If you are interested in addressing the question of "How did climate shape the movements, interactions, and evolution of hominin populations?" Come join my lab at the Human Origins Excellence Cluster in Tübingen🧬🧪. Details: uni-tuebingen.de/universitaet/k…

🧬We are born with hundreds of de novo DNA mutations that were not present in genomes of our parents. But why do some people have more of them than others? In a new preprint the authors analyzed 28,985 sibling pairs and identified more than 800,000 de novo mutations. The main factor is parental age especially paternal age with about 1.5 extra mutations per year of the father’s age and 0.4 per year of the mother’s age The authors did not find convincing evidence that the total number of de novo mutations is associated with genetic ancestry or parental smoking The most interesting part is rare variants in DNA repair and replication genes. Disruptive variants in REV1 were associated with about a 16% increase in the total mutation rate while variants in LIG1 were linked to a 24 to 26% increase in CpG to TpG mutations A key feature of the study was the analysis of IBD-segments in siblings genomic regions that both children inherited from the same parental chromosomes. Differences within these regions can point to new mutations. biorxiv.org/content/10.648… #deNovo #mutations #reparation #inheritance #siblings

Pan-African model explains Homo sapiens genetic and morphological evolution (preprint) biorxiv.org/content/10.110…

🚨FULLY FUNDED PHD POSITION!🚨 If you are interested in addressing the question of "How did climate shape the movements, interactions, and evolution of hominin populations?" Come join my lab at the Human Origins Excellence Cluster in Tübingen🧬🧪. Details: uni-tuebingen.de/universitaet/k…

Looking forward to participate on this panel discussion on Friday!

Sign Up - Neanderthal Evolution Symposium Crick Institute - May 15th docs.google.com/forms/d/e/1FAI…

"The regions in the Denisovan genome attributed to super-archaic introgression, are likely to have originated from H. erectus. Late Middle Pleistocene H. erectus may have coexisted with Denisovans." nature.com/articles/s4158…

"Hybridization in Animal Evolution" doi.org/10.32942/X21380

Want to do an experimental PHD on the evolution of human language? Only one more week left to submit your application!

Feel free to write to me if you have any questions. Deadline to apply is the 7th of June!

From diversity to flexibility: Seasonality as the forgotten dividend of Man the Hunter sciencedirect.com/science/articl…

In Eastern Africa, the cradle of humankind is tearing apart phys.org/news/2026-04-e… via @physorg_com

Malaria was fundamental in shaping the course of human evolution, @CamZoology researchers have found. From 74,000 to 5,000 years ago, early humans in Africa did not live in high-risk malaria areas. This shaped how populations met and mixed, leading to the population structure seen today. Read more about this new study in collaboration with the Max Planck Institute of Geoanthropology @MPI_GEA 👉 bit.ly/4e2V2PI

Very proud to be part of this amazing study led by Margherita Colucci, Eleanor Scerri and Andrea Manica, and very happy to finally see it out! 🤩

📣ATTENTION!!! Postdoc position on Creativity in Wild Chimpanzees and Bonobos 🤩@snsf_ch @UZH_en @univofstandrews Come join @APE_Group_UZH & Wild Minds Lab @NakedPrimate ✨Please RT✨ @EFPrimatology @PsgbStudent @BiologicalAnth @IPS_PrimateNews @PrimateEducate

🎥 Samantha Brown (CENIEH) explains how ZooMS refines the identification of fragmented faunal remains at Cova Eirós, improving our understanding of Neanderthal and Homo sapiens diets 🎥 Samantha Brown (CENIEH) explica cómo ZooMS permite identificar restos faunísticos fragmentados en Cova Eirós y mejorar la reconstrucción de la dieta de neandertales y Homo sapiens #ICTSNews

Another great pre-print today: "Effects of introgressed Neanderthal alleles on present-day brain morphology" Link here: biorxiv.org/content/10.648…

New paper alert. My new article just published in Quaternary Science Reviews, "Revolution, modernity, and the dispersal of Homo sapiens beyond Africa". sciencedirect.com/science/articl…