Ray Trapani

@Cathcapal @nicksortor I mean he’s not running again, what’s he need support on?

@nicksortor Wait. What? Does this mean Trump doesn't need her support anymore like the rest of us he dismissed?

🚨 BREAKING: First Lady Melania Trump PUBLICLY calls on Congress to ACT on the Epstein situation "Now is the time for Congress to ACT. Epstein was NOT alone." "I call on Congress to provide the women who have been victimized by Epstein with a PUBLIC HEARING specifically centered around the survivors. Give these victims their opportunity to testify UNDER OATH in front of congress with the power of sworn testimony. Each and every woman should have her day to tell her story in public if she wishes. And then her testimony should be permanently entered in to the congressional record."

@JJeffrey100 Yeah just used to be good on sonnet 4.6 or opus always, now it often gives circular advice, or just says the same wrong prompts. And I know for a fact it’s the same question I’ve asked before but now it gives me the wrong prompt repeatedly

@Raytrapani i moved to sonnet this morning. primarily to save tokens during peak (still ran out 3 hours in) BUT it one shotted a bug opus worked on for 30 mins yesterday. that's an n of 1... my prompt may have been more clear or something like that. but it did make me wonder

I swear Anthropic is scamming everyone lately with their api, no way opus just completely feels like it’s lowest model every time you speak to it now. But spends as if it’s still opus. Something’s off

@BasedBiohacker How do you like the Cerebrolysin? Unsure of what the other one is but lmk Never tried Cerebrolysin but always wanted to order some Everyone always speaks highly of Selank and Semax but they seem kinda mid

well well well, would you look at that as an adult, the closest you can come to the feeling of christmas morning as a kid is when fedex drops off a package with obscure pharmaceutical products from eastern europe

@patty_fi Been heavy on the last one, has my hollow cheeks coming in strong

I think people take way too many peptides This is all you need honestly BPC-157 TB-500 CJC-1295 Ipamorelin Tesamorelin Sermorelin GHK-Cu DSIP Epithalon Thymosin Alpha-1 PT-141 (Bremelanotide) Melanotan II AOD-9604 Fragment 176-191 GHRP-6 GHRP-2 Hexarelin Selank Semax LL-37 KPV Dihexa SS-31 (Elamipretide) MOTS-c Humanin Cerebrolysin Kisspeptin-10 GnRH (Gonadorelin) Oxytocin VIP (Vasoactive Intestinal Peptide) NAD+ Glutathione Pentosan Polysulfate Snap-8 Argireline Copper Peptides (GHK-Cu) Palmitoyl Pentapeptide Matrixyl Semaglutide Tirzepatide Retatrutide Survodutide Trenbolone​​​​​​​​​​​​​​​​ OxyContin

@orangie You gotta clean your bot

anthropic token costs are killing me but nothing runs my openclaw as good as opus haven’t tried gpt 5.4 yet , will give that a try today

@BagCalls Been taking basically all the same, plus GHK-CU just ordered some gluthione heard it helps with skin and stuff as well

Current Peptide Stack Reta 6 mg ( 3mg x2 per week) The bread and butter CJC/Ipamorelin 2.1mg (300mcg x7 per week) The additive NAD+ / 5amino1mq / MOTS-C 5mg ( 1mg x5 per week) Good energy, great rest, great recovery Selank 5mg ( 1mg x5 per week) Clarity, focus, not intense like Semax Also included: Test Cyp 200 mg per week ( 100 mg x2 per week) Soon adding: BPC-157 2-4 mg ( will return here for my shoulders on a 12 week cycle) TB -500 1 mg (help out the goat BPC) Sermoreling (more GH boost)

@fuulu92 @stalmico @m_goes_distance lol people on way more then GLPs and the other ones clearly work

@stalmico @m_goes_distance Probably only GLP-1-Agonists, they only big one actually proven to work.

peptides are the most underpriced asset in biotech right now - $328M grey market(it's actually 2x,3x,4x just can't prove it) - FDA can't stop it - science is catching up to the demand - every SF founder I know is on something named after 3 letters and a number the grey market becomes the market Invest in peptides NOW

Men only want one thing and it's this.

@ziwenxu_ Yessir

@Raytrapani That's business. Even if they don't want to, the board member will force them. 🤣

Anthropic just rebranded OpenClaw and called it "innovation." I’ve spent the day digging into the new Claude Managed Agents beta. The "revolutionary" architecture? It’s just the OpenClaw harness moved to their cloud and given a haircut. Here’s the reality behind the marketing: - Anthropic didn't win with better tech; they won with a paywall. By blocking OpenClaw from using flat-rate subscription limits last Saturday, they turned a community favorite into a massive API bill. - Anthropic's "Virtualized Auth" is great for production security your agent can push to Git but never "sees" your tokens. It’s the zero-trust standard, sure. - OpenClaw is where the real control stays. Keeping memory local in MEMORY.md means you own your agent's soul. Plus, you don't have to pay the "Claude Tax" if you want to swap to a local Llama or DeepSeek. Anthropic didn't kill OpenClaw with code. If you want a "managed" experience, go with Anthropic. If you want to actually own what you build, keep your hands dirty with OpenClaw.

@ziwenxu_ Yeah they been going hard that’s true. Guess just the way they view business. Free market, use every legal tactic possible

@Raytrapani Not really. Remember OpenClaw has to change name couple times because Claude? And it was before signing with OpenAI

@KaiXCreator Yes only worth it if you have a very clear focus on what you want to build or you have money to burn. I’ve spent over 20k in last month building my companies website and app. But it’s back end is Amazon level of flows

The more I use OpenClaw, the more I think it's not just hype. The only thing limiting me now is the API costs.

@WatcherGuru Somalians

JUST IN: 🇺🇸 Americans lost a record $11.36 billion to crypto-related fraud in 2025, up 22% from the previous year.

Always make sure to refresh and clean up your bot, go on Claude and say my claw bots spending to much money, ask how to check for where it’s spending excess money that you don’t need to spend. Clear the bloat Refresh the history on it regularly /reset If you just basically clear its cache of all the unused stuff cost goes down alot

@pmarca It’d be cool if someone made a wrapper for OpenClaw to cap token usage. Need a way to control the burn for simple tasks

Magical OpenClaw experiences that use frontier models cost $300-1,000/day today, heading to $10,000/day and more. The future shape of the entire technology industry will be how to drive that to $20/month.

@seeksharpe @elonmusk @pmarca Yes there is, there’s many

@elonmusk @pmarca there is literally 0 use cases to spend $200 a day on openclaw

@jmorin35 @vlelyavin @CasJam My exact thought

@vlelyavin @CasJam You know serious builders using ChatGPT free tier ?

Opus 4.6 is a fantastic model. Claude Code is an excellent harness. The Max plan is still a steal. I'm still shipping like crazy. I'm with the 99% of builders who'd rather be building than complaining about Anthropic's (frankly, pretty reasonable) terms.

@MorganGermani @CasJam What do they even refuse?

They literally don’t allow you to use it for general computer stuff anymore which is wild. Codex on the other hand can basically do anything for me. It’s able to help me with an insane amount of tasks that Claude now outright refuses. The only thing Claude has going for it is insane front end abilities which is awesome but it’s not enough considering everything else.

@Truth_Is_Treasn @MOSSADil @zerohedge Big country lots of bunkers, they planned for this for a long time. They are definitely decimated just shit ton of cheap missiles

@MOSSADil @zerohedge Shouldn’t “key” military infrastructure and leadership have already been taken out by now? If they were key, what were we waiting for?

‼️ NEW REPORT: Reports indicate over 100 U.S. and Israeli fighter jets are currently striking IRGC targets across Iran in what appears to be the most intense wave of airstrikes since the war began. A major escalation is underway as joint operations continue to target key military infrastructure and leadership.  Stay connected, follow @MOSSADil.

BPC 157 is probably the single most versatile peptide for women. It repairs gut lining, reduces inflammation systemwide, supports joint and connective tissue healing, and helps with skin quality. Women tend to deal with more gut issues and autoimmune conditions than men, so this one pulls double duty. If she’s also on a GLP 1 like Retatrutide or semaglutide, BPC 157 protects against the GI side effects. GHK Cu is the anti aging powerhouse. It stimulates collagen production, improves skin elasticity, promotes hair growth, and has strong anti inflammatory properties. After menopause, estrogen drops and collagen production tanks. GHK Cu directly addresses that by signaling your body to produce more collagen, elastin, and hyaluronic acid on its own. Sermorelin (or an Ipamorelin/CJC 1295 combo) stimulates the pituitary gland to release more natural growth hormone. For women this means better sleep, improved body composition, fat loss especially around the midsection, stronger hair and nails, and better skin. It works with your body’s natural feedback loop so it doesn’t push growth hormone to dangerous levels. If weight loss is the goal, Retatrutide is a game changer. It’s a triple agonist that hits GLP 1, GIP, and glucagon receptors all at once. Most GLP 1 drugs only hit one or two of those. The glucagon receptor activation is what sets Reta apart because it directly increases fat burning and energy expenditure on top of the appetite suppression. In clinical trials, participants lost up to 24% of their body weight. For women dealing with stubborn weight from hormonal shifts, menopause, or PCOS related insulin resistance, Reta attacks the problem from three different angles simultaneously. Start low at 0.5 mg weekly and titrate up slowly. Pair it with BPC 157 to protect your gut from the nausea and GI issues that come with any GLP 1, and stack Sermorelin alongside it so you’re preserving lean muscle mass while the fat comes off. That combo of Reta plus BPC 157 plus Sermorelin is probably the most effective weight loss stack a woman can run right now. As for estrogen and progesterone production specifically, no peptide directly manufactures estrogen or progesterone. Those are steroid hormones produced by the ovaries and adrenal glands. But Kisspeptin is the closest thing. It’s a neuropeptide that triggers GnRH release from the hypothalamus, which then signals the pituitary to release LH and FSH, which then tells the ovaries to produce estrogen and progesterone. It’s being studied clinically for women with hypothalamic amenorrhea and certain types of PCOS to restart ovulation and normalize hormone production. It works upstream of the whole reproductive hormone cascade rather than replacing hormones directly. The growth hormone peptides (Sermorelin, Ipamorelin) also indirectly support hormonal balance because better body composition, better sleep, and lower inflammation all create an environment where your body can produce its own hormones more efficiently. Bottom line: peptides don’t replace HRT, but they can optimize the foundation that hormone production depends on. A woman running BPC 157, GHK Cu, and Sermorelin is covering recovery, anti aging, and hormonal support all at once. Add Reta if fat loss is the priority and you’ve got a complete protocol.

@Raytrapani Awesome article. Very informative. For women what two or three that would be most beneficial? Also any petide that would help with estrogen production or progesterone production ?