Rosaria Sofia

Did you know CAG results after OHCA? 🚑🫀 Do not waste another second and run to read our article just published! #CAG #OHCA @ResusJournal resuscitationjournal.com/article/S0300-…

We managed a complex case of radial artery spasm (RAS). Based on this experience, we propose a step-wise approach to RAS @ccijournal. 📄Read the full article: onlinelibrary.wiley.com/doi/10.1002/ccd. #Radialarteryspasm #coronarycatheterization #deepsedation

Hemoglobinopathies @PedsCases #MedEd

How do we measure the severity of Mitral Regurgitation (MR)? Enter the PISA method. 1/ PISA = Proximal Isovelocity Surface Area It's a hemispheric zone of blood flow seen on color Doppler as it rushes toward a leaky mitral valve. The faster the flow, the more curved (and larger) this shell becomes. 2/ By adjusting the Doppler baseline toward the MR jet, we get a clearer PISA "dome." Measure the radius (r) of this dome—from the valve to the first color change (aliasing point). 3/ Use this formula to calculate the size of the leaky opening: EROA = (2πr² × Valiasing) / Vmax(MR jet) EROA = Effective Regurgitant Orifice Area A larger EROA = more severe MR. 4/ To calculate how much blood is leaking: Regurgitant Volume = EROA × VTI(MR) (VTI = total flow over time from the MR jet) 5/ Why it matters: - Helps assess MR severity - Guides treatment decisions - Combines well with other echo findings #Echo #Cardiology #PISA #MitralRegurgitation #CardioTwitter

Awake #ECMO in adults with respiratory failure, SR 📈 feasible & low failure risk in selected patients 🫁 mostly investigated in BT lung #transplantation (acceptable success), experimental in #ARDS 🫁 worsening respiratory failure, #delirium/agitation, bleeding most common reasons for failure; mortality almost 60% in patients who failed 📉 complications rate poorly reported 📖 bit.ly/3sEvsva With editorial on physiology-based indications to improve outcome of awake #ECLS 📖 bit.ly/3G6meLa #ICUrehab @CritCareMed

1/3 We assessed feasibility and safety of awake #ECMO without invasive ventilation in patients with severe respiratory failure 467 awake ECMO patients from 57 manuscripts are described in this article 🔗 Just published in @CritCareMed: journals.lww.com/ccmjournal/abs… #FOAMcc

@sofia_rosaria @ResusJournal @tscquizzato @giovannilandoni great job, Rosaria and team! When and if to intervene on coronary lesions in the setting of OHCA remains an important topic - glad to see this study.

WHAT ARE THE FINDINGS OF CAG AFTER OHCA?🫀 We performed a SRMA of 128 studies (>62k pts) to describe angiographic features in resuscitated and refractory OHCAs We found that 🔸 significant CAD is present in 75% 🔸 CAD is more severe in refractory OHCA 🔸 CAD is common also in pts with non-shockable rhythms and without ST↑ 📄 Just published @ResusJournal resuscitationjournal.com/article/S0300-… 🧵 Learn more in the thread 👇 #ResusTwitter #CardioTwitter #FOAMcc

Great teamwork produces great results at @SRAnesthesiaICU Thanks to all the team who help to study cardiac arrest and CPR: @sofia_rosaria @arianna_gazzato @alessanro_pruna @ABonaccorsoMD @MargheritaRoc10 and others We’re young but we’ve already achieved great results together

our Gianvito Martino @SanRaffaeleMI @MyUniSR published in @NatureMedicine a phase I study on #MultipleSclerosis safely intrathecally injecting neural precursor cells Interestingly, high dose neural cells was associated with lower rate of brain atrophy nature.com/articles/s4159…

Left ventricular longitudinal #strain could differentiate the prognosis after CABG in patients with preserved LVEF and provide significant incremental prognostic value to LVEF. jcvaonline.com/article/S1053-…

Pulmonary Thrombosis (not Pulmonary Embolism) (not Pulmonary Thromboembolism) #pulmonarythrombosis #microclots

More patients in the high dosing #PROTAMINE group received plasma (11 % vs 0 %; p=0.02) and platelet concentrate (21 % vs 6 %; p=0.04) compared to the low dosing #PROTAMINE group. Abundant protamine dosing increased postoperative blood loss pubmed.ncbi.nlm.nih.gov/27277211/

@MattDelNin @Dan_Landry @DrToddLee @BradSpellberg I think a correct approach should be "full anticoagulation in #covid19 outside the ICU, if the physician does not perceive increased bleeding risk" this is the phylosophy behind it twitter.com/SRAnesthesiaIC… and this is the EBM twitter.com/SRAnesthesiaIC… @DrToddLee

Evidence is accumulating that full anticoagulation in #covid19 #icu patients is not beneficial for survival pubmed.ncbi.nlm.nih.gov/36036760/ Please remember that evidence is accumulating that full anticoagulation in #covid19 patients outside the ICU is beneficial for survival

Validation of awake calibration of TOF monitoring ⚖️Awake calibration on one arm before anesthesia induction vs. anesthetized calibration on the other arm 🤝Close agreement in the duration to normalization between awake and anesthetized calibration 🔗doi.org/10.1097/ALN.00…

Our students, residents, anesthesiologists, intensivists, cardiologists, researchers, nurses, and every healthcare provider strongly support #WorldRestartAHeart @ERC_resus @Ilcor_org and #SettimanaViva @ircouncil 1️⃣ Check 2️⃣ Call 3️⃣ Compress … and use an AED ⚡️ #ResusTwitter

From #mechanical #afterload reduction to #prognostic oral drug in acute #HF: initiation of #ARNI therapy during #IABP support to enhance #MCS weaning is feasible and promising! 💊🫀@MarioGramegnaMD @guglielmogallo1 @CorstiaanU @davebaran

Our article is out. Will we find a way to protect the kidneys and prevent #AKI with continuous infusion of amino acids?   We’ve already randomized 2000/3500 patients in 16 centers. 🔗 authors.elsevier.com/a/1fiPM5WqQgwf… #PROTectionTrial #FOAMcc twitter.com/SRAnesthesiaIC…

Children had an higher #IQ (IQ=128) 2 weeks after general anesthesia when compared to before surgery (IQ=124) ⁉️ pubmed.ncbi.nlm.nih.gov/27080292/