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Angelica Parente
Angelica Parente@draparente·
This is really cool/necessary! First two indications I looked up had the wrong prevalence labels, though. Both diseases are more common than the assigned rare/ultra-rare labels. They were originally thought to be small populations, but higher prevalence numbers were published within the last few years.
Convoke@Convokebio

Today we're publishing our index of unmet needs in human disease: 2443 indications scored and ranked on burden of disease, prevalence, pipeline activity, and treatment burden. We hope this will help drug developers identify overlooked medical problems convoke.bio/blog/introduci…

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Alex Telford
Alex Telford@Atelfo·
@draparente Thanks! Do you mind sharing which ones? Agree that anchoring to highly visible/indexed sources is a problem with LLMs. Part of why we wanted to generate and share this is to identify areas where LLMs make mistakes
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Angelica Parente
Angelica Parente@draparente·
@Atelfo btw - love what you guys are doing! Wish you guys had individual accounts :)
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Alex Telford
Alex Telford@Atelfo·
@draparente We do! :) Thanks for the extra detail on the indications too, we'll look into it
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