Geschwind Lab @ UCLA

Thanks to Pico Caroni, @AllenInstitute and other organizers/sponsors for a great inaugural conference on the Neurobiology of Mental health. Fantastic program and setting in Thun, Switzerland. @LakeConferences

New in @ScienceMagazine: Our paper mapping gene/isoform/splicing regulation at pop-scale during human #neurodevelopment. Major developmental shifts in #genetic reg., New colocalized risk genes at ~60% of #psych #GWAS loci. #PsychENCODE24 science.org/doi/10.1126/sc…

Characterizing >100,000 sequences in primary neurons and organoids and deep learning to decode regulatory activity. Amazing work from @Chengyu_Deng_, @seawhalen, Katie Pollard, @LabNowakowski and others as part of #PsychENCODE in @ScienceMagazine. science.org/doi/10.1126/sc…

This represents the culmination of years of work by the @NIMHgov #PsychENCODE consortium! furthering our understanding into the genetic and molecular mechanisms of neuropsychiatric conditions🧠🧬 Read more in @ScienceMagazine: science.org/collections/ps… #Genomics #Neuroscience

Excited to announce our new pivotal work on autism in the latest #PsychENCODE collection, science.org/doi/10.1126/sc… see also @MarkGerstein, @mikejg84 #autism #genomics

Proud of our UCLA CART colleagues!

Our latest publication led by Yonatan Cooper identifying new dementia risk genes using MPRAs to screen noncoding GWAS variants of neurodegenerative disorders w/ functional validation in neurons and microglia @MartinUCSF @srikosuri @giovannicoppoIa science.org/doi/10.1126/sc…

Our latest publication from Chris Hartl characterizing brain-wide and brain region-specific gene co-expression, providing a framework to contextualize neuropsychiatric genetic risk, supporting polygenic models of disease go.nature.com/3iBPvkL @kasper_lage @alexisjbatte

Dr. Geschwind recently served as a witness in a congressional hearing coordinated by Congresswoman Karen Bass. His testimony focused on introducing Autism Spectrum Disorder. Take a few minutes to listen to Dr. Geschwind's statement: youtu.be/V7qgpVf-_EI?t=….

@choekatr @katycelina_ @RychlikJoshua Congrats, Katrina!!

Celebrating the Choe lab's first ever abstract submission to #SfN2021! My grad students @katycelina_ and @RychlikJoshua, co-first authors of this abstract, are absolute rockstars!! 🎸⭐🤘

Announcing the 1st Annual Conference on Precision Psychiatry! Grateful to our amazing speakers @NIMHDirector @AllofUsCEO @WrayNaomi @royperlis @GregSimonKPWHRI @clesemartin @CRodriguezMDPhD @GeschwindLab @tanzeemc @Stanford_PMHW + more! RT & Register here: mghcme.org/precision-psyc…

Our paper looking at the long-term maturation of cortical organoids is out! rdcu.be/cfDQt #organoids #brainorganoids TL;DR - human cortical organoids start to resemble postnatal cortical development after 250-300 days of culturing

Dr. Geschwind leads IPH and played a major role in securing this gift. We are very thankful to our donors, Dr. Allen and Charlotte Ginsburg! Read more: newsroom.ucla.edu/releases/ucla-…

Thrilled to share that UCLA received a $29M gift to establish a center within the Institute for Precision Health (IPH). which will enable Scientists & physicians to work side by side to examine the role of genetics in disease and develop therapies that improve patients’ lives.

Don't forget to join us for the Spring 2021 Seminar Series today at noon! Speaker is Daniel Geschwind, MD, PhD, from @UCLA. Here's the Zoom webinar link: wustl-hipaa.zoom.us/j/92588889033 #WashUGen @GeschwindLab

@UCLAHealth @GeschwindLab Making Sense of Sequencing: Exome Sequencing Analysis and What's Next. Listen to it here: bit.ly/2XIgOA4 Episode also available on @ApplePodcasts: apple.co/30PvU9C #geneexpression #genetics #genomics #sequencing #Findinggeniuspodcast

@jillhaney21 successfully defended her thesis today - woohoo! We couldn't be more proud of Jill, and we appreciate all the contributions she made to both @GeschwindLab and @GandalLabUCLA. Congratulations, Dr. Haney!

Now out! From @GeschwindLab @UCLA : Abnormal social and repetitive behaviors and elevated striatal dopamine, a molecular hallmark of human psychosis, in a Maternal Immune activation non-human primate model biologicalpsychiatryjournal.com/article/S0006-…

Proud and excited to share our work on multi-omic integration in Autism! 1/4 nature.com/articles/s4146…

My commentary on integrative genomics for the interpretation of genetic loci implicated in neurodevelopmental disorders is out today in @BiologicalPsyc1!! I had a lot of fun writing this and reflecting on all that I’ve learned from the great @GeschwindLab authors.elsevier.com/a/1bdLV1S07g1lU