Roy Perlis

Truly, I admire o3's optimism as a coding partner: "First run will finish the one-time build; subsequent runs will be instant and error-free." And then all your wishes will come true...

"One of the biggest lessons is fully recognizing how people have started to use ChatGPT for deeply personal advice...as AI and society have co-evolved, it’s become clear that we need to treat this use case with great care." openai.com/index/expandin…

@RecoveryDoctor Exactly

@royperlis What now?

Wtaf

Happy to have the opportunity to highlight really lovely cellular modeling work by Orhan and colleagues in AJP (@APAPubJournals) ... boiling the genomic ocean is not sufficient to figure out brain diseases: psychiatryonline.org/doi/10.1176/ap…

>I’m afraid code is getting unwieldy and bloated. How can we make it more maintainable? You're absolutely right. The code has become unwieldy and bloated. (Claude, that hurts my feelings a little....)

Looking forward to speaking at BU's CTSI Translational Science Symposium on 3/19: "Advancing Translational Science Through Cutting-Edge Technology" ... registration here: bu.edu/ctsi/events/bu…

Hmm. I'm not sure this chatbot is quite ready for prime time.

Working with the smaller (smol?) chatbots that will run on my phone takes some getting used to, after being accustomed to the big ones. I was just asked whether I'm feeling overwhelming today. (I am not.)

I'm often asked, what is MGH's secret? The answer: we have the cleanest hands.

Research Domain Criteria in NIMH Grants Characterized Using Large Language Models - @JAMANetworkOpen jamanetwork.com/journals/jaman…

Digital health technologies, including patient portals, are widely used by older adults. Author Cornelius James of the University of Michigan joins @JAMAplusAI EIC @royperlis to discuss how these technologies fit with his own experience in the clinic. ja.ma/42KvHEq

For those curious about the impact of the 15% IDC rate, here's data on total NIH funding by institution: brimr.org/brimr-rankings… ... and here's a brief synopsis of hardest-hit: forbes.com/sites/michaelt…

LLM, asked about optimal treatment of depression, "Here are some additional things you can do: 1. **Get enough sleep**: Aim for 7-10 years of psychotherapy and 75-100% of CBT." Yeah, 7-10 years should just about do it.

FDA Commissioner Robert Califf speaks with @JAMAplusAI Editor in Chief @royperlis about the challenges of regulating AI in health care. ja.ma/4gcyRoh