JaffreyLab

Congratulations Vladimir on his exciting paper characterising Cap2 methylation! Read it here: nature.com/articles/s4158…

Had a wonderful time at @Tri_I_RNA symposium today! Congratulations as well to Qian and Maxim for their successful talks at the symposium!

Come hear our graduate students, Qian and Maxim, speak at the next Tri-I RNA symposium amongst other talented RNA researchers!

P.S. if you're interested in Qian's research, come join us at the @Tri_I_RNA symposium this Friday!

Congratulations to Dr. Qian Hou on her successful defense! Qian has developed, characterised, and optimised an entire suite of RNA tools during her PhD, ranging from aptamer design to gene expression modulators. Congratulations on your amazing achievements!

Congratulations to Dr. @MildredUnti on her successful defense! Millie has produced an incredible system for mRNA therapeutics, alongside several tools during her PhD. Congratulations on your incredible contributions to the mRNA sphere!

Do you want to know how much of your favourite m6A site is methylated? You can find out in *one day* using @AashiqHMirza's new method, SCARPET! Find out more about it here: doi.org/10.1261/rna.07…

Surprising findings show phospholipids inside condensates throughout cells, not just in cell membranes, suggesting these compartments act as signaling centers, says Dr. Samie Jaffrey (@JaffreyLab) and colleagues. bit.ly/3RLES1t

Happy holidays everyone!

Also tried some interesting fruits that many of us have never had before! Recognise anything? (No, the pineapple doesn't count!)

Is that a really tiny Christmas tree, or an abundance of gigantic gifts?

@shino_murakami gave a wonderful talk at the @Tri_I_RNA symposium this Thursday about how mRNA translation can shape the transcriptome. Congratulations on the great talk! Thanks to the Tri-I RNA club for organising a wonderful symposium!

@MI_Shariful @shino_murakami @Tri_I_RNA Hello! Unfortunately this is only available to attend in person. Thank you for your interest though!

@JaffreyLab @shino_murakami @Tri_I_RNA Hello, It seems like a great symposium on RNA. Can you please tell me if it is possible to attend as a listener, via online?

Our lab's very own @shino_murakami will be giving a talk about the interplay between ribosomes, amino acids, and m6A at the @Tri_I_RNA mini symposium! Sign up to hear from her and other amazing RNA scientists here: buytickets.at/triirnaclub/10…

Ever wondered what types of metabolites could be enriched in condensates? Check out Jason's study, which gives us a first peek into the condensate metabolome. Congratulations Jason!

Oh no, someone grab the RNaseZAP!!! Dressed up this year as the most terrifying class of enzymes, the RNases! Even our circRNA couldn't escape the jaws of the endonucleases😢 Happy Halloween everyone!

So excited to announce that my most recent work has been published. If you’re interested in genetically encoding circular mRNA, or packaging circular mRNA into virus-like particles for cell-type specific delivery, this paper is for you!

Interested in expressing your mRNAs for a longer time? Want to have cell-specific targeting AND prolonged protein expression? Check out how @MildredUnti achieved this with translating circular mRNAs! Congratulations Millie!

I had a blast presenting my work at the @NYCRNASymposium. Overall a fantastic event with great science.

Also out today: Ryan's study on how long mRNAs partition into stress granules via m6A. Congratulations Ryan! Check it out here: nature.com/articles/s4159…