Tamara Zudaire

Ferruginous bodies in BAL. Dumbbell-shaped, golden yellow to black with Pap, blue with Perls an golden yellow with H&E. Happy to have seen them for the first time outside of the books! 😁 #cytopath #cytology

One of our brilliant residents showed me this case. Supraclavicular lymph node. No other clinical information at the moment. Micropapillary to papillary structures, some mitoses, some mucin production. (Short thread follows):

🍤#Pancreas #CytoQuiz🧐🧐🔬🔬 A) Pancreatic pseudocyst B) Lymphoepithelial cyst C) Serous cystadenoma D) Mucinous cystic neoplasm #Pathology #Cytology #PathTwitter Clue in caption 🧐

#CytoQuiz 🔬 #Pancreas🍤 A) Acinar Cell Carcinoma B) Solid Pseudopapillary Neoplasm C) Pancreatic Adenocarcinoma D) Pancreatic Neuroendocrine tumor #Pathology #Cytology Clue in caption 🧐

Asian male with enlarged node. FH with eosinophilic micro-abscesses. What's the IHC? #hemepath #pathelective #forfun

🔬 #CytoQuiz 19-year-old with a firm nodule on the index finger. A) Granular Cell Tumor B) Epithelioid Sarcoma C) Epithelioid Angiosarcoma D) Clear Cell Sarcoma

#CytoQuiz 🔬🧐 A) Myxoid Liposarcoma B) Extraskeletal myxoid chondrosarcoma C) Myxofibrosarcoma D) Chordoma #Pathology #Cytology Clue in caption 🧐

#CytoQuiz #BreastPath🔬🧐 A) Ductal Carcinoma B) Fat Necrosis C) Phyllodes Tumor D) Fibroadenoma #Cytopath clue in caption 🧐

70 yo M no relevant PMH. Buccal mucosa ulcer biopsy (see H&E). Waiting on GMS. Do you buy cryptococcus? @ParasiteGal @LangerPath

BMB 41 yo male. All these cells are positive for CD3, CD5, CD2, CD7. In the pics you can see the CD4 and CD8. What is your diagnosis? What other stains would you like to see?

More on anaplastic large cell lymphoma (ALCL) mimickers: Enteropathy associated T-cell lymphoma (EATL) may exhibit anaplastic morphology, with pronounced inflammatory background consisting of histiocytes, eosinophils, small lymphocytes, and plasma cells. Furthermore, EATLs with large cell or anaplastic morphology are often CD30+ and sometimes EMA+. In the setting of a localized mass to the gastrointestinal tract and history of celiac disease, EATL would be on top of the differential, even if the morphology and strong CD30-positivity are reminiscent of ALCL. However, in rare instances, where EATL with anaplastic morphology presents with involvement of extra-gastrointestinal organs, this could cause serious diagnostic challenges, as illustrated in this report @Histo_Journal➡️pubmed.ncbi.nlm.nih.gov/26531107/ #hemepath #pathology #pathX #pathtwitter #lymsm #MedEd #SoMe

Illustration of a case of Burkitt lymphoma in the intestine with characteristic variable/ patchy SOX11 expression pattern. SOX11 may come in handy in tricky cases when you need more evidence to push for Burkitt lymphoma vs other mimickers #hemepth #lmsm #pathtwitter #PathX #MedX

Unicentric Castleman disease-plasma cell variant:Preserved overall lymph node architecture and marked plasmacytosis in interfollicular areas,with a subset germinal centers showing regressive changes reminiscent of Castleman disease-hyaline vascular variant #Hemepath #HemepathMDA

What do you see in the interfollicular region of this lymph node? What is the most likely etiology for this finding? #hemepath

Axillary LN, 29 yo woman. What are the arrows pointing at?

Follicular lymphoma with BCL2 rearrangement by FISH & unusual overexpression of CCND1 by IHC (CD5 & SOX11 negative; CCND1 rearrangement negative by FISH). This rare finding has been reported previously➡️shorturl.at/lzDOU but is worth to be aware of #hemepath #lymsm #PathX

Relapsed classic Hodgkin lymphoma (CHL) with brighter PAX5 expression then typically accepted for CHL, and associated new emerging follicular lymphoma in the same lymph node biopsy (bottom right of Figure 1) #hemepath #lymsm #pathX #MedX #SoMe #Surgpath #MedTwitter #Pathtwitter

Follicular lymphoma with abundant extracellular eosinophilic material, mimicking amyloid deposition: An unsual variant to be aware of #hemepath #lymsm #pathtwitter #MedEd #SoMe Check a similar but more prominent case by @sanamloghavi @BloodJournal➡️ ashpublications.org/blood/article/…

Large B-cell lymphoma involving the testicle with a germinal center-like phenotype (CD10+BCL6+MUM1-): May occur in < 10% of primary large B-cell lymphoma of the testis, however, it should raise the suspicion of disseminated systemic DLBCL #hemepath #lymsm #surgpath #Pathx #MedX

Primary large B-cell lymphoma of the CNS: Cyclin-D1 highlights endothelial cells in brain tissue, however its pattern of expression could be misinterpreted as positivity in neoplastic cells. Comparison to MUM1 & PAX5 is helpful to avoid this pitfall #hemepath #lymsm #PathX

Salivary gland "Acinic Cell Carcinoma" may occasionally assumes a very "histiocytic" appearance on FNA, as nicely shown in this case. DD in such scenario includes - Mucoepidermoid CA, Secretory CA, Metastatic RCC and Benign cyst with macrophages.