PataniLab

Our latest @Brain1878: Elevated 4R tau drives neurodegeneration in VCP-related frontotemporal dementia. Link: academic.oup.com/brain/advance-… Led by the very talented Dr Christy Hung (currently applying for faculty positions!) @Patanilab @The_MRC @UCLIoN @mndassoc @MNDoddie5 @TheCrick

'Human VCP mutant #ALS/#FTD #microglia display immune and #lysosomal phenotypes independently of GPNMB' Benjamin E. Clarke & Oliver J. Ziff...Rickie Patani @RickiePatani @PataniLab @TheCrick @UCLIoN bit.ly/4i3Md7T

Explore RNA regulation in neuronal development integrating microscopy, transcriptome and interactome-wide analyses Postdoctoral Research Fellow opportunity in the laboratory of Professor Andres Ramos: Link: ucl.ac.uk/work-at-ucl/se…

Glad to see our review on the use of omics to study glia in ALS led by the superb Stan Majewski (not on X/Twitter) out in @GLIA_Journal! @PataniLab @TheCrick @UCLIoN onlinelibrary.wiley.com/doi/10.1002/gl…

Family Fun with the Patani lab @TheCrick !🧬🧑‍🧑‍🧒‍🧒 Come, check out our boardgame and discover your stem cell potential!🔬🧫 #DiscoveryDay

Free tomorrow? Why not come to the Crick for family fun at Discovery Day! @PataniLab will be there 11-4 - come and play our stem cell game 🧫🧪🔬

@PataniLab @MNDoddie5 Upadated call details here: ucl.ac.uk/work-at-ucl/se…

Still looking for a talented and enthusiastic bioinformatician to work with us on a super exciting project on DNA damage and RNA metabolism in motor neuron disease. @PataniLab All details here: ucl.ac.uk/work-at-ucl/se… closing on 9th may! @UCLIoN @TheCrick

We are hiring! The @PataniLab is looking for a bioinformatician to work on an exciting project on RNA metabolism and DNA damage in ALS funded by @MNDoddie5, all detalis here: ucl.ac.uk/work-at-ucl/se… still a few days left to apply!

@giulia_tyzack @MNDoddie5 A great opportunity to join a dynamic team with the brilliant and talented @giulia_tyzack. Our core values: integrity, innovation and delivery; join us in making some exciting & impactful discoveries with fantastic collaborators inc. Simon Boulton @MNDoddie5 @UCLIoN @TheCrick

APP antisense oligonucleotides reduce Aβ aggregation and rescue endolysosomal dysfunction in induced pluripotent stem cells derived from people with Alzheimer disease academic.oup.com/brain/advance-…

"There is an urgent and unmet need for discovery of disease mechanisms in ALS in order to inform new treatment strategies. Our study is a powerful example of how interdisciplinarity and team science can catalyse such discoveries." - @PataniLab More ⬇️ bit.ly/48qwASn

Also massive thanks to @ListerInstitute that supports both myself and @RickiePatani and brought us together, playing a massive role in this study!

Thank you @h_dunning for covering our recent @NatureComms paper on RNA-mediated aggregation in ALS, work led by the amazing @FedericaRaguseo and in collaboration with the great @DiMicheleLAB1, @RickiePatani @FA_Aprile and @YuvalElani imperial.ac.uk/news/250293/un…

We're thrilled that collaboration between our #ListerFellows @DiAntonioLAB1 and @PataniLab has contributed to this @NatureComms paper on the role of unusual RNA in #ALS. Congratulations to all involved 🧑‍🔬🎉🧬🎓 nature.com/articles/s4146…

We're so pleased to be able to bring great minds together @DiAntonioLAB1 @RickiePatani

Unravelling what goes wrong in #MND is key to creating a world free of MND. @PataniLab are investigating whether DNA damage plays a role in MND development and progression. @mndassoc is proud to fund research which could pave the way to explore new potential therapies. More ⬇

It’s Dr Neuroblonde now! 👩‍⚕️Yesterday I successfully defended my PhD! 🎓 Immense gratitude to my incredible examiners @SelinaWray and @krista_rantanen for their insightful questions and making the Viva so enjoyable. Thank you @PataniLab @uclbbk_mrcdtp. Let the next chapter begin!

Thrilled and incredibly grateful to have recently started a 3 year MND biomedical research project grant from the @mndassoc I was awarded with @RickiePatani to continue investigating the mechanisms of glial dysfunction in MND. 🧪🧠🧑‍🔬@PataniLab @mndresearch

Our latest @Brain1878: Elevated 4R tau drives neurodegeneration in VCP-related frontotemporal dementia. Link: academic.oup.com/brain/advance-… Led by the very talented Dr Christy Hung (currently applying for faculty positions!) @Patanilab @The_MRC @UCLIoN @mndassoc @MNDoddie5 @TheCrick

Finally, and most importantly, this work is the result of a multi-collaborative effort and it could have not been possible without the amazing @DiMicheleLAB1, @PataniLab, @FA_Aprile and @YuvalElani. Thank you all for your support!