Sebastian Brandner

@nancyk121 Yes, I spent 2years in Neurosurgery where I learned craniotomies and importantly discovered my passion for neuropathology 🔬

@AlexFellows1 @DervisSalih1 Beautiful!

Discovery of drug response in IDH mutant gliomas with a potential to treat astrocytomas and oligodendrogliomas. cancerres.aacrjournals.org/content/early/… Very pleased that this has just been published in CANCER RESEARCH. Will be in Pubmed soon.

Mutant IDH sensitizes gliomas to endoplasmic reticulum stress and triggers apoptosis by MicroRNA183-mediated inhibition of Semaphorin 3E cancerres.aacrjournals.org/content/early/…

Methylation array profiling of adult brain tumours: diagnostic outcomes in a large, single centre app.peer.us/papers/public/…

I think it may be more common than previously thought. Just need to observe carefully and connect the facts.

Indeed, important and groundbreaking finding that change the view on transmissible proteopathies

nature.com/articles/s4138… Inhibition of GPR158 by microRNA-449a suppresses neural lineage of glioma stem/progenitor cells and correlates with higher glioma grades

rdcu.be/NGwB: GPR 158 and miR-449 as new brain tumour malignancy bio-markers and possible therapeutic targets

It was an interesting and engaging event. Well done! twitter.com/mtvc2/status/9…

nature.com/articles/s4138… Inhibition of GPR158 by microRNA-449a suppresses neural lineage of glioma stem/progenitor cells and correlates with higher glioma grades: Possible new therapeutic target and biomarker.

Inhibition of GPR158 by microRNA449a suppresses neural lineage of glioma stemprogenitor null tinyurl.com/y7q26nw3 #DTHSTR

#stem_cells_GBM_papers / #miRNA_GBM_papers: Inhibition of GPR158 by microRNA-449a suppresses neural lineage of glioma stem/progenitor cells and correlates with higher glioma grades Oncogene 2018 rdcu.be/NpaA

Inhibition of GPR158 by microRNA-449a suppresses neural lineage of glioma stem/progenitor cells and correlates with higher glioma grades. ift.tt/2rjVMXS #Neuralstemcells

Next step: to update with new subclasses. twitter.com/M_Preusser/sta…

We are not changing that much actually. Of 400 tumours in our lab, we changed diagnosis on 20%. And these 400 are a 10% selection already. So, no worries we'll stick with WHO 2016 for most tumours for a while twitter.com/DrPaolini/stat…

@DrPaolini @DrMMB @thebigcobb @sam_albadri @neuropathology @MelanieBoisMD @ActaNeuropathol They look beautiful. But rarely done. Even in large centres.

@chromosomeOMICS @NatureGenet Yes, usually works on FFPE. we have done 400 in the last 2 years!

and we thought: let's look into this in more detail. link.springer.com/article/10.100…

then we saw this nhs.uk/news/neurology…