ludovic vallier

New paper from @VallierLab is online. "Acquisition of epithelial plasticity in human chronic liver diseases". Amazing work from @chrisgrbbn and @VasileiosGalan in collaboration with @imohorianu and Mike Alison. Few key points: 1/ link.springer.com/article/10.103…

We are delighted to launch the Roger Williams Institute of Liver Studies Clinical Catalyst Scheme! Designed to provide research-qualified health professionals, not currently undertaking any substantial research activity, the opportunity to form a collaborative, high-quality research partnership with established biomedical and applied health researchers within the RW-ILS and with protected time and funding to enhance their research skills and experience. Applicants must be employed by one of the King’s Health Partners NHS Foundation Trusts (King’s College Hospital NHS FT, Guy’s and St Thomas’ NHS FT, or South London and Maudsley NHS FT) as registered senior health professionals at consultant level or Band 7 equivalent or above (e.g. nurses, midwives, doctors, dentists, pharmacists, healthcare scientists, psychologists and any other registered professions allied to healthcare). Eligible applicants cannot currently be undertaking any substantial research activity. Projects can range from basic discovery science to translational and applied health research, but must align with the RW-ILS’ research themes. Full details & application process: liver-research.org.uk/grants_funding… Application deadline: 5pm Monday 16th March

Love the new cover of Nature Reviews Gastroenterology & Hepatology, featuring our Human Cell Atlas roadmap paper, Towards a reference cell atlas of liver diversity over the human lifespan. The article is also currently free to access (with registration) until 24th January.

In June's #EditorsChoice, Laetitia Pinte, @VallierLab & co investigate the function of EHF transcription factor in #LungHomeostasis and #LungDisease. ⚡ doi.org/10.1242/dmm.05… 📰 doi.org/10.1242/dmm.05…

Very happy to host Fotis Sampaziotis (Cambridge Stem Cell Institute) on the 11/11 at BCRT. All are welcome to join. Title: "Deciphering fibrosis in bioengineered organs’" When: 11/11 2025 What: Talk at 1pm Where: Auditorium@Cranach Haus, Föhrer Str. 15, 13353 Berlin

Tomorrow the first Berlin symposium on organoids will take place @ BCRT/BIH/Charite. Program: bihealth.org/en/notices/ber…. I will present a summary of our work on liver organoids. : "Everything you always wanted to know about liver organoids (but you were afraid to ask)".

Looking forward to present the work of the lab at the lac leman regenerative medicine symposium: habiblab.org/l2rm Title of my talk: "CELL-BASED THERAPY AGAINST LIVER DISEASES AND BEYOND". I hope that the beyond got your intrigued, me too.

So, we (Dylan Liabeuf and Anastasiia Maksiuk) are organising the first Berlin symposium on organoids. The objective is to bring together the Berlin organoid community and to develop further interactions. Info: bihealth.org/en/notices/ber… Free registration: bihealth.org/en/news/events…

The website and the report for the German National Strategy for Gene- and Cell-based Therapies is now available: nationale-strategie-gct.de/en/ If you want to know how Germany will develop these key therapies.

Looking forward to join the 10th International Symposium on Primate Research in Kunming from the 15th to 18th of August. The title of my talk: Fibrosis: developmental biology breaking bad. New data showing importance of dev mechanisms in disease. mm.sciconf.cn/en/minisite/in…

Very promising news on the next seven-year EU budget, with a proposed substantial increase for Horizon Europe including the ERC. We are analysing the other parts of this proposal in more detail. @Vonderleyen @EZaharievaEU research-and-innovation.ec.europa.eu/news/all-resea…

The latest paper @VallierLab is now online. This tour de force from the amazing Laetitia Pinte (supervised by @martavilagonz ) uncover the function of EHF in the lung (not a liver story!) epithelium using hiPSCs, genome editing, and lung organoids. doi.org/10.1242/dmm.05…

Results for ERC advanced grants. UK is back in the lead with 56 funded projects and Germany is second with 35 grants! Success rate 11%. Hopefully the ERC budget will significantly increase to attract scientists from outside EU. erc.europa.eu/news-events/ne…

Drs. Yong He, Yingfen Chen, and Frank Tacke #review current data related to the immunological mechanisms of #MASLD. They summarize the effects of current and experimental therapies on immunoregulation in MASLD. 💊 go.nature.com/3ZTdFh6

Join us today June 4th 1 pm for Irina Mohorianu talk at BCRT* Auditorium on "RoSignOL: Robust Signature of Life A Gene regulatory network-centric collection of robust and scalable frameworks for the analysis of high-throughput datasets" *Föhrer Str. 15, 13353 Berlin

My single-author review is open in Special issue: Extraembryonic tissue in DB - covers issues on human amnion & extraembryonic mesoderm. Hand-drawn Fig1 compares them with mice. *Contact me for seq data in our SciAd paper missed by cyberattack to UnivCam. #fig1" target="_blank" rel="nofollow noopener">sciencedirect.com/science/articl…

A great collaborative effort from @RSeguiLab’s PhD students Silvio Traba and Lucas Bacigalupo, working with @VallierLab ! 🎉🔬 @agenciaidiar @CONICETDialoga @PancreaticCell #PancreasResearch #DevelopmentalBiology #CienciaArgentina #SinCienciaNoHayFuturo #CienciaEsSoberania

Thrilled to announce a major milestone for our lab @ifibyne @Exactas_UBA — our paper on the glucocorticoid receptor's role in early pancreas development is now published in @Dev_journal! Huge thanks to @VallierLab for this long-term collaboration!👇🧵 🔗 doi.org/10.1242/dev.20…

Somite is building the blueprints to create any cell type for any person. We call it DeltaStem, our foundation model for the human cell. Our proprietary capsule technology allows us to generate cell signaling data 1,000x faster and more efficiently than current methods, accelerating discovery and optimization of cell production for treatment of diseases like type 1 diabetes, osteoarthritis, and DMD. DeltaStem allows us to reliably generate previously inaccessible cell types for the first time, unlocking a foundry of human spare parts. To scale DeltaStem and bring it into therapeutics, we’re excited to share that we’ve raised over $47M in Series A funding. Our round was led by Khosla Ventures, with participation from SciFi VC, the Chan Zuckerberg Initiative, Fusion Fund, Ajinomoto Group Ventures, Pitango HealthTech, TechAviv, Harpoon Ventures, along with angel investors such as Dr. R. Martin Chavez (former Chairman of Recursion), and Fidji Simo (outgoing CEO of Instacart and incoming CEO of Applications at OpenAI). Somite was founded and is led by a team of AI entrepreneurs and developmental biologists: Dr. Micha Breakstone, a repeat AI entrepreneur, Dr. Jonathan Rosenfeld, leader of the Fundamental AI Group at MIT, and a distinguished group of scientific co-founders representing institutions like Harvard Medical School and the National Academies of Science and Medicine. We look forward to collaborating with strategic partners who share our vision of leveraging AI for a new age in human repair. Reach out: somite.ai

Lab gathering today to celebrate a big milestone—our paper on the glucocorticoid receptor’s role in early pancreas development is now accepted in Development! 🎉🔬 More details coming soon! #Science #DevelopmentalBiology

Don't miss the "4th International Symposium on Regenerative Hepatology". Amsterdam May 6, 2024. Excellent program featuring hepatocyte organoid expansion, hepatic cellular plasticity in regeneration, microRNAs, and gene therapy for liver disease etc.. regenerativehepatology.com